¿Cuál es el origen de la COVID-19?
(What is the origin of covid-19)
Primeras 5 respuestas:
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The recently emerged SARS-CoV-2 (Coronaviridae; Betacoronavirus) is the underlying cause of COVID-19 disease.
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SARS-CoV-2 with potential origin of bat is still circulating in China.
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COVID-19 has taken the world by storm in the ongoing pandemic.
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This virus associated symptoms and infectious respiratory illness is designated as coronavirus disease 19 (COVID-19).
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COVID-19 has become a global pandemic caused by a novel coronavirus SARS-CoV-2.
The recently emerged SARS-CoV-2 (Coronaviridae; Betacoronavirus) is the underlying cause of COVID-19 disease.
... The recently emerged SARS-CoV-2 (Coronaviridae; Betacoronavirus) is the underlying cause of COVID-19 disease. Here we assessed SARS-CoV2 from the Kingdom of Saudi Arabia alongside sequences of SARS-CoV, bat SARS-like CoVs and MERS-CoV, the latter currently detected in this region. Phylogenetic analysis, natural selection ...
Ref: Insights into molecular evolution recombination of pandemic SARS-CoV-2 using Saudi Arabian sequences [bioRxiv, 2020-05-13]SARS-CoV-2 with potential origin of bat is still circulating in China.
... BACKGROUND: Coronavirus can cross the species barrier and infect humans with a severe respiratory syndrome. SARS-CoV-2 with potential origin of bat is still circulating in China. In this study, a prediction model is proposed to evaluate the infection risk of non-human-origin ...
Ref: Using the spike protein feature to predict infection risk and monitor the evolutionary dynamic of coronavirus [Infect Dis Poverty, 2020]COVID-19 has taken the world by storm in the ongoing pandemic.
... COVID-19 has taken the world by storm in the ongoing pandemic. The virus responsible for COVID-19 disease is "severe acute respiratory syndrome coronavirus-2" SARS-CoV-2, an enveloped RNA beta-coronavirus from the family Coronaviridae. There have been similar beta-coronavirus disease outbreaks previously: Severe ...
Ref: The genetic landscape of COVID-19: A South Asian perspective. [JPMA. The Journal of the Pakistan Medical Association, 2020-05-01]This virus associated symptoms and infectious respiratory illness is designated as coronavirus disease 19 (COVID-19).
... emerged as a global pandemic in short span with alarming levels of spread and severity. This virus associated symptoms and infectious respiratory illness is designated as coronavirus disease 19 (COVID-19). The SARS-CoV-2 possesses enveloped club-like spike protein projections with positive-sense large RNA genome and has ...
Ref: The current understanding and potential therapeutic options to combat COVID-19 [Life Sci, 2020]COVID-19 has become a global pandemic caused by a novel coronavirus SARS-CoV-2.
... COVID-19 has become a global pandemic caused by a novel coronavirus SARS-CoV-2. Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis and for drug discovery and vaccine development. We show evidence of strong purifying selection around the receptor binding motif ...
Ref: Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection [bioRxiv, 2020-03-21]World Health Organization has declared the ongoing outbreak of coronavirus disease 2019 (COVID-19) a Public Health Emergency of International Concern.
... World Health Organization has declared the ongoing outbreak of coronavirus disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Committee on Taxonomy of Viruses. Human infection with SARS-CoV-2 leads to a wide range of clinical ...
Ref: A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses [Emerg Microbes Infect, 2020]Origin of the COVID-19 virus has been intensely debated in the scientific community since the first infected cases were detected in December 2019.
... Origin of the COVID-19 virus has been intensely debated in the scientific community since the first infected cases were detected in December 2019. The disease has caused a global pandemic, leading to deaths of thousands of people across the world and thus finding origin of this novel coronavirus is important in responding and ...
Ref: Origin of Novel Coronavirus (COVID-19): A Computational Biology Study using Artificial Intelligence [bioRxiv, 2020-05-15]The emergence of a novel coronavirus, SARS-CoV-2, resulted in a pandemic.
... The emergence of a novel coronavirus, SARS-CoV-2, resulted in a pandemic. Here, we used X-ray structures of human ACE2 bound to the receptor-binding domain (RBD) of the spike protein (S) from SARS-CoV-2 to predict its binding to ACE2 proteins from different ...
Ref: Comparison of SARS-CoV-2 spike protein binding to ACE2 receptors from human, pets, farm animals, and putative intermediate hosts [J. virol, 2020]The origin of severe acute respiratory syndrome-associated corona-virus (SARS-CoV) is still a matter of speculation,
... The origin of severe acute respiratory syndrome-associated corona-virus (SARS-CoV) is still a matter of speculation, although more than one year has passed since the onset of the SARS outbreak. In this study, we implemented a 3-step strategy to test the intriguing hypothesis that SARS-CoV might ...
Ref: Testing the hypothesis of a recombinant origin of the SARS-associated coronavirus [Arch Virol, 2004-10-11]Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses an immediate, major threat to public health across the globe.
... Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses an immediate, major threat to public health across the globe. Here we report an in-depth molecular analysis to reconstruct the evolutionary origins of the enhanced pathogenicity of SARS-CoV-2 and other coronaviruses that are severe human pathogens. Using integrated comparative genomics ...
Ref: Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses [Proc. Natl. Acad. Sci. U. S. A, 2020]In 2003, severe acute respiratory syndrome coronavirus (SARS-CoV) caused one of the most devastating epidemics known to the developed world.
... In 2003, severe acute respiratory syndrome coronavirus (SARS-CoV) caused one of the most devastating epidemics known to the developed world. There were two important lessons from this epidemic. Firstly, coronaviruses, in addition to influenza viruses, can cause severe and rapidly spreading human infections. Secondly, bats can serve as the origin ...
Ref: From SARS coronavirus to novel animal and human coronaviruses. [Journal of thoracic disease, 2013]The novel human coronavirus disease COVID-19 has become the fifth documented pandemic since the 1918 flu pandemic.
... Abstract The novel human coronavirus disease COVID-19 has become the fifth documented pandemic since the 1918 flu pandemic. COVID-19 was first reported in Wuhan, China, and subsequently spread worldwide. The coronavirus was officially named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Committee on Taxonomy ...
Ref: COVID-19: the First Documented Coronavirus Pandemic in History [Biomed J, 2020-05-05]Human coronaviruses (HCoVs) were first described in the 1960s for patients with the common cold.
... Human coronaviruses (HCoVs) were first described in the 1960s for patients with the common cold. Since then, more HCoVs have been discovered, including those that cause severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), two pathogens that, upon infection, can cause fatal ...
Ref: Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses [Trends Microbiol, 2016-03-21]COVID-19 as an acute respiratory infectious disease,
... total of 6,467,229 cases of COVID-19 have been confirmed worldwide including 382,766 deaths (WHO, 2020). COVID-19 as an acute respiratory infectious disease, primarily spreads by the mean of the respiratory tract, via droplets, respiratory secretions emitted from ...
Ref: Novel SARS-CoV-2/COVID-19: Origin, pathogenesis, genes and genetic variations, immune responses and phylogenetic analysis [Gene Rep, 2020-06-15]The origin of the SARS‐CoV‐2 virus remains enigmatic.
... The origin of the SARS‐CoV‐2 virus remains enigmatic. It is likely to be a continuum resulting from inevitable mutations and recombination events. These genetic changes keep developing in the present epidemic. Mutations tending to deplete the genome in ...
Ref: SARS‐CoV‐2 variants: Relevance for symptom granularity, epidemiology, immunity (herd, vaccines), virus origin and containment? [Environ Microbiol, 2020-05-19]Coronavirus disease 2019 (COVID-19) is a global health concern as it continues to spread within China and beyond.
... Coronavirus disease 2019 (COVID-19) is a global health concern as it continues to spread within China and beyond. The causative agent of this disease, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), belongs to the genus Betacoronavirus, which also includes severe acute respiratory syndrome-related coronavirus (SARSr-CoV) and Middle East ...
Ref: Multivariate analyses of codon usage of SARS-CoV-2 and other betacoronaviruses [Virus Evol, 2020-05-14]The ongoing COVID-19 pandemic originated in Wuhan, Hubei Province, China in December 2019.
... The ongoing COVID-19 pandemic originated in Wuhan, Hubei Province, China in December 2019. The etiologic agent is a novel coronavirus of presumed zoonotic origin with structural similarity to the viruses responsible for severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). ...
Ref: COVID-19 and the clinical hematology laboratory [Int. j. lab. hematol, 2020]The original coronavirus disease (COVID-19) outbreak in Wuhan, China has become a global pandemic.
... The original coronavirus disease (COVID-19) outbreak in Wuhan, China has become a global pandemic. By tracking the earliest 118 COVID-19 cases in Canada, we produced a Voronoi treemap to show the travel origins of the country"s earliest COVID-19 cases. By March 11, 2020, even ...
Ref: Tracking the origin of early COVID-19 cases in Canada [Int. j. infect. dis, 2020]The virus is the etiological agent of an infectious 31 respiratory disease termed coronavirus disease 19 (COVID-19).
... globally from an initial outbreak of severe 30 pneumonia centered on Wuhan, Hubei Province, China. The virus is the etiological agent of an infectious 31 respiratory disease termed coronavirus disease 19 (COVID-19). On March 11 th 2020, due to its alarming 32 spread and severity across most ...
Ref: Proteolytic cleavage of the SARS-CoV-2 spike protein and the role of the novel S1/S2 site [iScience, 2020-05-28]The novel coronavirus, SARS-CoV-2, causes the unfathomable pandemic in the history of humankind.
... The novel coronavirus, SARS-CoV-2, causes the unfathomable pandemic in the history of humankind. Bangladesh is also a victim of this critical situation. To investigate the genomic features of the pathogen, the first complete genome of the virus has very recently been published. Therefore, ...
Ref: Understanding the possible origin and genotyping of first Bangladeshi SARS-CoV-2 strain. [Journal of medical virology, 2020-06-03]The coronavirus disease (COVID-19) is highly pathogenic viral infection caused by SARS-CoV-2.
... The coronavirus disease (COVID-19) is highly pathogenic viral infection caused by SARS-CoV-2. Currently, COVID-19 has caused global health concern. It is assumed that COVID-19 has zoonotic origin based on the large number of infected people who were exposed to the wet market ...
Ref: Novel coronavirus disease (COVID-19): a pandemic (epidemiology, pathogenesis and potential therapeutics) [New Microbes New Infect, 2020-04-14]Severe acute respiratory syndrome (SARS) is a deadly form of pneumonia caused by a novel coronavirus,
... Severe acute respiratory syndrome (SARS) is a deadly form of pneumonia caused by a novel coronavirus, a viral family responsible for mild respiratory tract infections in a wide variety of animals including humans, pigs, cows, mice, cats, and birds. Analyses to date have been unable to ...
Ref: Mosaic evolution of the severe acute respiratory syndrome coronavirus. [Journal of virology, 2004]Coronaviruses (CoVs) cause a broad spectrum of diseases in domestic and wild animals, poultry, and rodents,
... Coronaviruses (CoVs) cause a broad spectrum of diseases in domestic and wild animals, poultry, and rodents, ranging from mild to severe enteric, respiratory, and systemic disease, and also cause the common cold or pneumonia in humans. Seven coronavirus species are known to cause human infection, 4 ...
Ref: Coronaviruses and SARS-COV-2 [Turk J Med Sci, 2020]Near the end of 2019, the novel coronavirus SARS-CoV-2 began transmitting among humans.
... A deadly pathogen has found a new host. Near the end of 2019, the novel coronavirus SARS-CoV-2 began transmitting among humans. In the first two months following its discovery, over 75,000 cases of COVID-19 causing over 2,000 deaths have been confirmed. Researchers rapidly ...
Ref: A glimpse into the origins of genetic diversity in SARS-CoV-2 [Clin Infect Dis, 2020-03-04]Bats have been identified as a natural reservoir for an increasing number of emerging zoonotic viruses, including henipaviruses and variants of rabies viruses.
... Bats have been identified as a natural reservoir for an increasing number of emerging zoonotic viruses, including henipaviruses and variants of rabies viruses. Recently, we and another group independently identified several horseshoe bat species (genus Rhinolophus) as the reservoir host for a large number of viruses that have a close genetic relationship with ...
Ref: Review of Bats and SARS [Emerg Infect Dis, 2006-12-19]The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by infection with human coronavirus 2019
... The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by infection with human coronavirus 2019 (HCoV-19 / SARS-CoV-2 / 2019-nCoV), is a global threat to the human population. Here, we briefly summarize the available data for the zoonotic origins of HCoV-19, with reference to the ...
Ref: Zoonotic origins of human coronavirus 2019 (HCoV-19 / SARS-CoV-2): why is this work important? [Zool Res, 2020-05-19]The origin of the SARS-CoV-2 virus remains enigmatic.
... The origin of the SARS-CoV-2 virus remains enigmatic. It is likely to be a continuum resulting from inevitable mutations and recombination events. These genetic changes keep developing in the present epidemic. Mutations tending to deplete the genome in ...
Ref: SARS-CoV-2 variants: Relevance for symptom granularity, epidemiology, immunity (herd, vaccines), virus origin and containment? [Environ Microbiol, 2020]To explore potential intermediate host of a novel coronavirus is vital to rapidly control continuous COVID-19 spread.
... To explore potential intermediate host of a novel coronavirus is vital to rapidly control continuous COVID-19 spread. We found genomic and evolutionary evidences of the occurrence of 2019-nCoV-like coronavirus (named as Pangolin-CoV) from dead Malayan Pangolins. Pangolin-CoV is 91.02% and 90.55% identical at the whole genome level ...
Ref: Pangolin homology associated with 2019-nCoV [bioRxiv, 2020-02-20]A novel coronavirus emerged in human populations and spread rapidly to cause the global coronavirus disease 2019 pandemic.
... A novel coronavirus emerged in human populations and spread rapidly to cause the global coronavirus disease 2019 pandemic. Although the origin of the associated virus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) remains unclear, genetic evidence suggests that bats are a reservoir host of the virus, and pangolins ...
Ref: COVID-19 and veterinarians for one health, zoonotic- and reverse-zoonotic transmissions [J Vet Sci, 2020-05-22]Auxiliar no entendimento da COVID-19 em relação à origem do SARS-CoV-2,
... Objetivo: Auxiliar no entendimento da COVID-19 em relação à origem do SARS-CoV-2, suas descobertas genômicas, patogenia, possíveis hospedeiros primários e intermediários, além da comparação com outros coronavírus Metodos: foram utilizadas as bases de dados Scientific Eletronic Library Online e PubMed, com ...
Ref: As descobertas genômicas do SARS-CoV-2 e suas implicações na pandemia de COVID-19 [J. Health Biol. Sci. (Online), 2020]The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern.
... The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps ...
Ref: A Genomic Perspective on the Origin and Emergence of SARS-CoV-2 [Cell, 2020]The disease caused by SARS-CoV-2, COVID-19, ranges from asymptomatic infection to severe respiratory failure 5 .
... facing the largest CoV pandemic caused by SARS-CoV-2 with millions of cases throughout the world. The disease caused by SARS-CoV-2, COVID-19, ranges from asymptomatic infection to severe respiratory failure 5 . In the early infection phases, anti-SARS CoV IgG and IgM are produced within a period ...
Ref: The Novel Coronavirus SARS‐CoV‐2: From a Zoonotic Infection to Coronavirus Disease‐19 (COVID19) [J Med Virol, 2020-05-29]Coronavirus disease 2019 (COVID-19), has spread over 210 countries and territories beyond China shortly.
... Coronavirus disease 2019 (COVID-19), has spread over 210 countries and territories beyond China shortly. On February 29, 2020, the World Health Organization (WHO) denoted it in a high-risk category, and on March 11, 2020, this virus was designated pandemic, after its declaration being a ...
Ref: COVID-19: animals, veterinary and zoonotic links. [The veterinary quarterly, 2020-05-12]World Health Organisation (WHO) on 11 Feb 20 named this disease caused by SARS-CoV-2 as Covid-19.
... caused by SARS-CoV-2, a strain of Coronaviruses (CoVs) belonging to subgenus Sarbecovirus of genus Betacoronavirus. World Health Organisation (WHO) on 11 Feb 20 named this disease caused by SARS-CoV-2 as Covid-19. This pandemic is spreading rapidly and more than 20,00,000 cases have occurred globally. The human ...
Ref: SARS-CoV-2: Camazotz's Curse [Med J Armed Forces India, 2020-04-27]A novel coronavirus SARS-CoV-2 is associated with the current global pandemic of Coronavirus Disease 2019 (COVID-19).
... A novel coronavirus SARS-CoV-2 is associated with the current global pandemic of Coronavirus Disease 2019 (COVID-19). Spike protein receptor-binding domain (RBD) of SARS-CoV-2 is the critical determinant of viral tropism and infectivity. To investigate whether the mutations in the RBD have altered the receptor binding affinity ...
Ref: Emergence of RBD mutations in circulating SARS-CoV-2 strains enhancing the structural stability and human ACE2 receptor affinity of the spike protein [bioRxiv, 2020-04-20]The origin of this new virus is presumed zoonotic, with bats being its probable vector.
... coronavirus. This new coronavirus was called SARS-CoV-2 and the disease it produces was named COVID-19. The origin of this new virus is presumed zoonotic, with bats being its probable vector. Due to the rapid number of infections and deaths that occurred first in China and ...
Ref: Pandemia COVID-19, la nueva emergencia sanitaria de preocupación internacional: una revisión./ [Pandemic COVID-19, the new health emergency of international concern: a review] [SEMERGEN, Soc. Esp. Med. Rural Gen. (Ed. Impr.), 2020]Infections with bat-origin coronaviruses have caused severe illness in humans by ‘host jump’.
... Infections with bat-origin coronaviruses have caused severe illness in humans by ‘host jump’. Recently, novel bat-origin coronaviruses were found in pigs. The large number of mutations on the receptor-binding domain allowed the viruses to infect the new host, posing a potential threat to ...
Ref: Bat-Origin Coronaviruses Expand Their Host Range to Pigs [Trends in Microbiology, 2018-06-30]Yet, the origin of SARS-CoV-2 remains mysterious.
... disease 2019 (COVID-19) caused by SARS-CoV-2 has posed a severe threat to global public health. Yet, the origin of SARS-CoV-2 remains mysterious. Several recent studies (e.g., Lam et al.,Xiao et al.) identified SARS-CoV-2-related viruses in pangolins, providing ...
Ref: Pangolins Harbor SARS-CoV-2-Related Coronaviruses [Trends Microbiol, 2020-04-06]the origin of SARS-CoV-2 remains mysterious.
... 2019 (COVID-19) caused by SARS-CoV-2 has posed a severe threat to global public health. Yet, the origin of SARS-CoV-2 remains mysterious. Several recent studies (e.g., Lam et al.,Xiao et al.) identified SARS-CoV-2-related viruses in pangolins, providing ...
Ref: Pangolins Harbor SARS-CoV-2-Related Coronaviruses [Trends Microbiol, 2020-04-06]La enfermedad por coronavirus 2019, es una enfermedad respiratoria aguda con una amplia gama de manifestaciones:
... La enfermedad por coronavirus 2019, es una enfermedad respiratoria aguda con una amplia gama de manifestaciones: desde un simple resfriado, pasando por una neumonía leve, moderada o grave, hasta sepsis, shock séptico o la muerte Inició presuntamente en un mercado de animales vivos en la ciudad ...
Ref: SARS-CoV-2: origen, estructura, replicación y patogénesis [Alerta (San Salvador), 2020]COVID-19 presents as fever, dry cough, dyspnea, headache and pneumonia.
... lives. The virus was named SARS-CoV-2 in February by International Committee on Taxonomy of Viruses. COVID-19 presents as fever, dry cough, dyspnea, headache and pneumonia. In a small subset of severe cases, the disease quickly progresses to respiratory failure and ...
Ref: [Diagnosis, treatment, control and prevention of SARS-CoV-2 and coronavirus disease 2019: back to the future] [Sheng Wu Gong Cheng Xue Bao, 2020]The disease produced by SARS-CoV-2, originated in China, was termed as COVID-19 (a respiratory disease).
... The disease produced by SARS-CoV-2, originated in China, was termed as COVID-19 (a respiratory disease). The clinical presentation of COVID-19 is highly variable and may not manifest as in asymptomatic virus carrier, a form with Acute Respiratory Disease (ARD) and typical pneumonia of protean severity. ...
Ref: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Emergence, History, Basic and Clinical Aspects [Saudi J Biol Sci, 2020-04-23]There is rising global concern for the recently emerged novel Coronavirus (2019-nCov).
... There is rising global concern for the recently emerged novel Coronavirus (2019-nCov). Full genomic sequences have been released by the worldwide scientific community in the last few weeks in order to understand the evolutionary origin and molecular characteristics of this virus. Taking ...
Ref: Genomic variance of the 2019-nCoV coronavirus [bioRxiv, 2020-02-04]Recently, a novel coronavirus (2019-nCoV) has emerged from Wuhan, China,
... Recently, a novel coronavirus (2019-nCoV) has emerged from Wuhan, China, causing symptoms in humans similar to those caused by severe acute respiratory syndrome coronavirus (SARS-CoV). Since the SARS-CoV outbreak in 2002, extensive structural analyses have revealed key atomic-level interactions between ...
Ref: Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus [J. virol, 2020]The emerging coronavirus disease (COVID-19) swept across the world, affecting more than 200 countries and territories.
... The emerging coronavirus disease (COVID-19) swept across the world, affecting more than 200 countries and territories. Genomic analysis suggests that the COVID-19 virus originated in bats and transmitted to humans through unknown intermediate hosts in the Wuhan seafood market, China, in December of 2019. This virus ...
Ref: The Human Coronavirus Disease COVID-19: Its Origin, Characteristics, and Insights into Potential Drugs and Its Mechanisms [Pathogens, 2020-04-29]There is a rising global concern for the recently emerged novel coronavirus (2019-nCoV).
... There is a rising global concern for the recently emerged novel coronavirus (2019-nCoV). Full genomic sequences have been released by the worldwide scientific community in the last few weeks to understand the evolutionary origin and molecular characteristics of this virus. Taking advantage of ...
Ref: Genomic variance of the 2019-nCoV coronavirus [J Med Virol, 2020]Coronavirus disease‐2019 (COVID‐19) outbreak due to novel coronavirus or severe acute respiratory syndrome
... Coronavirus disease‐2019 (COVID‐19) outbreak due to novel coronavirus or severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has come out as a major threat for mankind in recent times. It is continually taking an enormous toll on mankind by means of increasing number ...
Ref: In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs [J Med Virol, 2020-05-17]Coronaviruses are the well-known cause of severe respiratory, enteric and systemic infections in a wide range of hosts
... Coronaviruses are the well-known cause of severe respiratory, enteric and systemic infections in a wide range of hosts including man, mammals, fish, and avian. The scientific interest on coronaviruses increased after the emergence of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) outbreaks in 2002-2003 followed by Middle East Respiratory ...
Ref: Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments [Vet Q, 2020]Bats are presumed reservoirs of diverse coronaviruses (CoVs)
... Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of COVID-19. However, the evolution and diversification of these coronaviruses remains poorly understood. We used a Bayesian ...
Ref: Origin and cross-species transmission of bat coronaviruses in China [bioRxiv, 2020-05-31]The recent outbreak of coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2,
... The recent outbreak of coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2, had raised great concern. 1 Although the virus appears to be less pathogenic than MERS-CoV and SARS-CoV, it shows a better efficacy of human-to-human transmission. 2 -4 WHO raised the ...
Ref: Strategies to trace back the origin of COVID-19 [J Infect, 2020-04-08]An ongoing outbreak of pneumonia caused by a novel coronavirus,
... An ongoing outbreak of pneumonia caused by a novel coronavirus, currently designated as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was reported recently. However, as SARS-CoV-2 is an emerging virus, we know little about it. In this review, we summarize ...
Ref: SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat [Int J Biol Sci, 2020]The ongoing global pandemic of infection disease COVID-19 caused by the 2019 novel coronavirus
... The ongoing global pandemic of infection disease COVID-19 caused by the 2019 novel coronavirus (SARS-COV-2, formerly 2019-nCoV) presents critical threats to public health and the economy since it was identified in China, December 2019. The genome of SARS-CoV-2 had been sequenced and structurally annotated, ...
Ref: Dinucleotide repeats in coronavirus SARS-CoV-2 genome: evolutionary implications [Int J Biol Sci, 2020-05-30]The city of Wuhan, Hubei province, China, was the origin of a severe pneumonia outbreak in December 2019,
... The city of Wuhan, Hubei province, China, was the origin of a severe pneumonia outbreak in December 2019, attributed to a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]), causing a total of 2761 deaths and 81109 cases (25 February 2020). SARS‐CoV‐2 belongs to genus Betacoronavirus, subgenus ...
Ref: An exclusive 42 amino acid signature in pp1ab protein provides insights into the evolutive history of the 2019 novel human‐pathogenic coronavirus (SARS‐CoV‐2) [J Med Virol, 2020-03-20]The severe acute respiratory syndrome coronavirus (SARS-CoV) first emerged in 2003,
... The severe acute respiratory syndrome coronavirus (SARS-CoV) first emerged in 2003, causing the SARS epidemic which resulted in a 10% fatality rate. The advancements in metagenomic techniques have allowed the identification of SARS-like coronaviruses (SL-CoVs) sequences that share high homology to ...
Ref: Understanding bat SARS-like coronaviruses for the preparation of future coronavirus outbreaks — Implications for coronavirus vaccine development [Human Vaccines & Immunotherapeutics, 2016-11-10]Coronavirus disease-2019 (COVID-19) outbreak due to novel coronavirus or severe acute respiratory syndrome
... Coronavirus disease-2019 (COVID-19) outbreak due to novel coronavirus or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has come out as a major threat for mankind in recent times. It is continually taking an enormous toll on mankind by means of increasing number ...
Ref: In silico studies on the comparative characterization of the interactions of SARS-CoV-2 spike glycoprotein with ACE-2 receptor homologs and human TLRs [J. med. virol, 2020]The emergence and rapid spread of novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2
... The emergence and rapid spread of novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a potentially fatal disease is swiftly evolving public health crises worldwide. The origin of SARS-CoV-2 infection was first reported in people exposed to wet animal market in Wuhan ...
Ref: Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2): A global pandemic and treatments strategies [Int J Antimicrob Agents, 2020]The new decade of the 21st century (2020) started with the emergence of a novel coronavirus known as SARS-CoV-2
... The new decade of the 21st century (2020) started with the emergence of a novel coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease (COVID-19) in Wuhan, China. It is the third highly pathogenic and transmissible coronavirus after severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East ...
Ref: Emergence of a Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2: Biology and Therapeutic Options [J. clin. microbiol, 2020]The human pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the major pandemic of the 21st century.
... The human pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the major pandemic of the 21st century. We analyzed >4,700 SARS-CoV-2 genomes and associated meta-data retrieved from public repositories. SARS-CoV-2 sequences have a high sequence identity (>99.9%), which drops to >96% when compared to bat coronavirus. We ...
Ref: The impact of super-spreaders in COVID-19: mapping genome variation worldwide [bioRxiv, 2020-06-12]Since end of December 2019, a cluster of patients with pneumonia of unknown origin was reported from Wuhan, Hubei province, China.
... Since end of December 2019, a cluster of patients with pneumonia of unknown origin was reported from Wuhan, Hubei province, China. As of Feb 17th, 2020, statistical data show that the outbreak constitutes an epidemic threat in China, where the exponential increase in patients has reached 75114 confirmed cases, with 2239 ...
Ref: 2019 Novel coronavirus infection and gastrointestinal tract [J Dig Dis, 2020-03-10]The emergence of a novel strain of betacoronavirus, SARS-CoV-2,
... The emergence of a novel strain of betacoronavirus, SARS-CoV-2, has led to a pandemic that has been associated with hundreds of thousands of deaths. Research is ongoing around the world to create vaccines and therapies to minimise rates of ...
Ref: CoV-AbDab: the Coronavirus Antibody Database [bioRxiv, 2020-05-15]The causative agent of COVID-19 is a novel coronavirus known as SARS-CoV-2.
... disease has rapidly acquired a pandemic status affecting almost all populated areas of the planet. The causative agent of COVID-19 is a novel coronavirus known as SARS-CoV-2. The virus has an approximate 30 kb single-stranded positive-sense RNA genome, which is 74.5% to ...
Ref: Origin, Potential Therapeutic Targets and Treatment for Coronavirus Disease (COVID-19) [Pathogens, 2020-04-22]All seven HCoVs have a zoonotic origin from bats, mice or domestic animals [2, 20] .
... All seven HCoVs have a zoonotic origin from bats, mice or domestic animals [2, 20] . Multiple lines of evidence support an evolutionary origin of all HCoVs from bats, where viruses are well adapted and non-pathogenic but show great genetic diversity. The COVID-19 epidemic has presented ...
Ref: Zoonotic origins of human coronaviruses [Int J Biol Sci, 2020-03-15]Coronavirus infections of multiple origins have spread to date worldwide, causing severe respiratory diseases.
... Coronavirus infections of multiple origins have spread to date worldwide, causing severe respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, SARS-CoV, MERS-CoV, and SARS-CoV-2. Among them, SARS-CoV and MERS-CoV caused outbreaks in 2002 and 2012, respectively. SARS-CoV-2 (COVID-19) ...
Ref: Overview of lethal human coronaviruses [Signal Transduct Target Ther, 2020]The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2
... The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could ...
Ref: COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses [J Adv Res, 2020-03-16]The coronavirus disease 2019 (COVID-19) outbreak caused by SARS-CoV-2 has triggered global panic.
... The coronavirus disease 2019 (COVID-19) outbreak caused by SARS-CoV-2 has triggered global panic. We have conducted an anonymous online survey of Asian medical students in Poland to assess whether they experience any form of prejudice related to the ongoing pandemic. As demonstrated, the ...
Ref: COVID-19-related prejudice toward Asian medical students: A consequence of SARS-CoV-2 fears in Poland [J Infect Public Health, 2020]Coronavirus disease (COVID-19) is caused by SARS-COV2
... Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to ...
Ref: The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak [J Autoimmun, 2020-02-26]A novel coronavirus has caused thousands of human infections in China since December 2019, raising a global public health concern.
... A novel coronavirus has caused thousands of human infections in China since December 2019, raising a global public health concern. Recent studies (Huang et al., Chan et al., and Zhou et al.) have provided timely insights into its origin and ability to spread among humans, informing infection prevention and control ...
Ref: Unveiling the Origin and Transmission of 2019-nCoV [Trends Microbiol, 2020-02-24]China announced an outbreak of new coronavirus in the city of Wuhan on December 31, 2019;
... BACKGROUND: China announced an outbreak of new coronavirus in the city of Wuhan on December 31, 2019; lash to now, the virus transmission has become pandemic worldwide. Severe cases from the Huanan Seafood Wholesale market in Wuhan were confirmed pneumonia with a novel coronavirus (2019-nCoV). Understanding ...
Ref: Genomic analysis and comparative multiple sequences of SARS-CoV2 [J Chin Med Assoc, 2020]The outbreak of COVID-19 originated from Wuhan City, Hubei province, in China.
... The outbreak of COVID-19 originated from Wuhan City, Hubei province, in China. Fifty-five percent of the infected cases before 1 January 2020 were linked to the Huanan Seafood Wholesale Market. However, the first human-to-human case of SARS-CoV-2 infection reported on 1 December ...
Ref: The COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiology, Diagnosis, Treatment, and Control [J Clin Med, 2020-04-24]A cluster of severe pneumonia of unknown etiology in Wuhan City, Hubei province in China emerged in December 2019.
... A cluster of severe pneumonia of unknown etiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as the causative agent. The current outbreak of infections with SARS-CoV-2 is termed ...
Ref: Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19) [Clin Exp Pediatr, 2020-04-02]The ongoing episode of coronavirus disease 19 (COVID-19) has imposed a serious threat to global health and the world economy.
... The ongoing episode of coronavirus disease 19 (COVID-19) has imposed a serious threat to global health and the world economy. The disease has rapidly acquired a pandemic status affecting almost all populated areas of the planet. The causative agent of COVID-19 is a novel coronavirus known as SARS-CoV-2. The virus ...
Ref: Origin, Potential Therapeutic Targets and Treatment for Coronavirus Disease (COVID-19) [Clin Exp Pediatr, 2020]The new disease produced by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) represents a major pandemic event nowadays.
... The new disease produced by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) represents a major pandemic event nowadays. Since its origin in China in December 2019, there is compelling evidence that novel SARS-CoV-2 is a highly transmissible virus, and it is associated to a broad clinical spectrum going ...
Ref: Is the kidney a target of SARS-CoV-2? [Am J Physiol Renal Physiol, 2020]severe acute respiratory syndrome coronavirus (SARS-CoV) caused one of the most devastating epidemics known to the developed world.
... In 2003, severe acute respiratory syndrome coronavirus (SARS-CoV) caused one of the most devastating epidemics known to the developed world. There were two important lessons from this epidemic. Firstly, coronaviruses, in addition to influenza viruses, can cause severe and rapidly spreading human infections. Secondly, bats can serve as ...
Ref: From SARS coronavirus to novel animal and human coronaviruses. [Journal of thoracic disease, 2013]The emergence and rapid spread of COVID-19 signifies a perfect epidemiological storm.
... The emergence and rapid spread of COVID-19 signifies a perfect epidemiological storm. A respiratory pathogen of relatively high virulence from a virus family that has an unusual knack of jumping species boundaries, that emerged in a major population center and travel hub ...
Ref: A Genomic Perspective on the Origin and Emergence of SARS-CoV-2 [Cell, 2020-04-16]COVID-19 is emerged as a respiratory infection and a suspicious origin of animals and transmission to human in Wuhan, China on December 2019.
... virulent disease rising its transmission and fatality with each passing day in the worldwide population. COVID-19 is emerged as a respiratory infection and a suspicious origin of animals and transmission to human in Wuhan, China on December 2019. Later this, the virus was transmitted from person to person through droplets and contacts. The ...
Ref: The effect of COVID-19 on global population and its fatality rate: Retrospective study by online database [Indian J Med Sci, 2020-04-30]The new disease produced by the Severe Acute Respiratory Syndrome - coronavirus 2 (SARS-CoV-2) represents a major pandemic event nowadays.
... The new disease produced by the Severe Acute Respiratory Syndrome - coronavirus 2 (SARS-CoV-2) represents a major pandemic event nowadays. Since its origin in China in December 2019, there is compelling evidence that novel SARS-CoV-2 is a highly transmissible virus, and it is associated to a broad clinical spectrum going ...
Ref: Is the kidney a target of SARS-CoV-2? [American journal of physiology. Renal physiology, 2020-05-15]A new human coronavirus, SARS-CoV-2, was quickly identified,
... affected greater than 40,000 people, and killed more than 1,000 as of Feb. 10, 2020. A new human coronavirus, SARS-CoV-2, was quickly identified, and the associated disease is now referred to as coronavirus disease discovered in 2019 (COVID-19) ...
Ref: No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2 [Emerg Microbes Infect, 2020-02-26]We showed that severe acute respiratory syndrome coronavirus 2 is probably a novel recombinant virus.
... We showed that severe acute respiratory syndrome coronavirus 2 is probably a novel recombinant virus. Its genome is closest to that of severe acute respiratory syndrome-related coronaviruses from horseshoe bats, and its receptor-binding domain is closest to that of pangolin viruses. Its origin and direct ...
Ref: Possible Bat Origin of Severe Acute Respiratory Syndrome Coronavirus 2. [Emerging infectious diseases, 2020-04-21]COVID-19 pandemic sources:
... Council «Life Science» of the Russian Academy of Science: Lvov D.K., Alkhovsky S.V., Burtseva E.I. COVID-19 pandemic sources: origin, biology and genetics of coronaviruses of SARS-CoV, SARS-CoV-2, MERS-CoV (Conference hall of Presidium of ...
Ref: [Source of the COVID-19 pandemic: ecology and genetics of coronaviruses (Betacoronavirus: Coronaviridae) SARS-CoV, SARS-CoV-2 (subgenus Sarbecovirus), and MERS-CoV (subgenus Merbecovirus).] [Voprosy virusologii, 2020]a novel coronavirus (2019-nCoV) has emerged from Wuhan, China,
... Recently, a novel coronavirus (2019-nCoV) has emerged from Wuhan, China, causing symptoms in humans similar to those caused by severe acute respiratory syndrome coronavirus (SARS-CoV). Since the SARS-CoV outbreak in 2002, extensive structural analyses have revealed key atomic-level interactions ...
Ref: Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus [J. virol, 2020]The new Corona-virus, recently called the severe acute respiratory syndrome Coronavirus (SARS-CoV-2) appears for the first time in China
... The new Corona-virus, recently called the severe acute respiratory syndrome Coronavirus (SARS-CoV-2) appears for the first time in China and more precisely in Wuhan (December 2019). This disease can be fatal. Seniors, and people with other medical conditions (diabetes, heart disease ), may be more vulnerable and become seriously ...
Ref: Moroccan Medicinal plants as inhibitors against SARS-CoV-2 main protease: Computational investigations [J Biomol Struct Dyn, 2020]It is caused by a novel coronavirus named SARS-CoV-2 with elusive origin.
... Background COVID-19 has become a worldwide pandemic. It is caused by a novel coronavirus named SARS-CoV-2 with elusive origin. SARS-CoV-2 infects mammalian cells by binding to ACE2, a transmembrane protein. Therefore, the conservation of ACE2 and its expression pattern across mammalian species, ...
Ref: Atlas of ACE2 gene expression in mammals reveals novel insights in transmisson of SARS-Cov-2 [bioRxiv, 2020-03-31]In late December 2019, Chinese health authorities reported an outbreak of pneumonia of unknown origin in Wuhan, Hubei Province.
... BACKGROUND: In late December 2019, Chinese health authorities reported an outbreak of pneumonia of unknown origin in Wuhan, Hubei Province. SUMMARY: A few days later, the genome of a novel coronavirus was released (http://virological.org/t/novel-2019-coronavirus-genome/319; Wuhan-Hu-1, GenBank accession No. MN908947) and made publicly available to the scientific community. This novel ...
Ref: COVID-19 Outbreak: An Overview [Chemotherapy, 2020-04-07]SARS-CoV-2 began spreading in December 2019 and has since become a pandemic that has impacted many aspects of human society.
... BACKGROUND: SARS-CoV-2 began spreading in December 2019 and has since become a pandemic that has impacted many aspects of human society. Several issues concerning the origin, time of introduction to humans, evolutionary patterns, and underlying force driving the SARS-CoV-2 outbreak remain unclear. METHOD: Genetic variation in 137 SARS-CoV-2 genomes and ...
Ref: The origin and underlying driving forces of the SARS-CoV-2 outbreak [J Biomed Sci, 2020]The current CoV disease 2019 (COVID-19) epidemic is discussed in this context.
... compare and contrast the different HCoVs from a perspective of virus evolution and genome recombination. The current CoV disease 2019 (COVID-19) epidemic is discussed in this context. In addition, the requirements for successful host switches and the implications of virus evolution on ...
Ref: Zoonotic origins of human coronaviruses [Int J Biol Sci, 2020]Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
... Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new infectious disease that first emerged in Hubei province, China, in December 2019, which was found to be associated with a large seafood and animal market in Wuhan. ...
Ref: The genetic sequence, origin, and diagnosis of SARS-CoV-2 [Eur. j. clin. microbiol. infect. dis, 2020]What is known so far about the origin of the virus that causes COVID 19?
... facts. The COVID-19 pandemic that has hit virtually all the globe has been no exception. What is known so far about the origin of the virus that causes COVID 19? The first investigations on the origin of this disease have determined that it is a ...
Ref: [What is the origin of SARS-CoV-2?] [Revista medica del Instituto Mexicano del Seguro Social, 2020-01-01]Wuhan, the city in Hubei province in China is in the focus of global community due to the outbreak of coronavirus disease 2019
... Wuhan, the city in Hubei province in China is in the focus of global community due to the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), formerly known as 2019-nCoV. The virus emerged in humans from Wuhan seafood market probably via zoonotic transmission. Within a few days ...
Ref: Emergence of deadly severe acute respiratory syndrome coronavirus-2 during 2019–2020 [Virusdisease, 2020-04-08]The novel coronavirus (SARS-CoV-2) originating from Wuhan rapidly spread throughout China.
... OBJECTIVES: The novel coronavirus (SARS-CoV-2) originating from Wuhan rapidly spread throughout China. While its origin remains uncertain, accumulating evidence links a wet market for the early SARS-CoV-2 spread in Wuhan. Similarly, the influence of the marketplace on the early transmission dynamics ...
Ref: Effect of the Wet Market on the coronavirus disease (COVID-19) transmission dynamics in China, 2019-2020 [Int. j. infect. dis, 2020]Coronavirus can cross the species barrier and infect humans with a severe respiratory syndrome.
... BACKGROUND: Coronavirus can cross the species barrier and infect humans with a severe respiratory syndrome. SARS-CoV-2 with potential origin of bat is still circulating in China. In this study, a prediction model is proposed to evaluate the infection risk of non-human-origin coronavirus for early ...
Ref: Using the spike protein feature to predict infection risk and monitor the evolutionary dynamic of coronavirus [Infect Dis Poverty, 2020]The excess of low frequency 117 mutations is consistent with the recent origin of SARS-CoV-2 [19].
... mutations, the latter 116 mainly exhibits an excess of low frequency changes (Fig. 1a) . The excess of low frequency 117 mutations is consistent with the recent origin of SARS-CoV-2 [19]. Both population 118 reduction and positive selection can increase high frequency mutations [20, 21] . ...
Ref: The origin and underlying driving forces of the SARS-CoV-2 outbreak [bioRxiv, 2020-04-14]Special attention has been paid to bat coronaviruses as the two emerging coronaviruses which have caused unexpected human disease outbreaks in the 21st century,
... Bats have been recognized as the natural reservoirs of a large variety of viruses. Special attention has been paid to bat coronaviruses as the two emerging coronaviruses which have caused unexpected human disease outbreaks in the 21st century, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), are suggested to ...
Ref: Bat origin of human coronaviruses [Virol J, 2015-12-22]The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan city, China in December 2019
... The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan city, China in December 2019 and thereafter its spillover across the world has created a global pandemic and public health crisis. Today, it appears as a threat to human civilization. Scientists and medical practitioners across ...
Ref: Deep phylogenetic analysis of Orthocoronavirinae genomes traces the origin, evolution and transmission route of 2019 novel coronavirus [bioRxiv, 2020-05-15]In late December 2019, the world woke to a reality of a pandemic of Coronavirus Disease (COVID-19),
... In late December 2019, the world woke to a reality of a pandemic of Coronavirus Disease (COVID-19), elicited by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which belongs to a group of ß-coronavirus. The potential to cause life-threatening respiratory failure and rapid transmission puts COVID-19 in ...
Ref: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Emergence, History, Basic and Clinical Aspects [bioRxiv, 2020]Every time a pandemic occurs, dozens of theories emerge to attribute the origin of the event to different facts.
... Every time a pandemic occurs, dozens of theories emerge to attribute the origin of the event to different facts. The COVID-19 pandemic that has hit virtually all the globe has been no exception. What is known so far about the origin of the virus that causes COVID 19? The ...
Ref: [What is the origin of SARS-CoV-2?] [Revista medica del Instituto Mexicano del Seguro Social, 2020-01-01]On 23 September 2012, the World Health Organization (WHO) announced the discovery of a new coronavirus, MERS-CoV,
... viruses have likely been circulating in humans for a long time prior to their discovery. On 23 September 2012, the World Health Organization (WHO) announced the discovery of a new coronavirus, MERS-CoV, in two patients who died from a mysterious, rapidly-fatal disease in the Middle East [3] ...
Ref: Coronaviruses: emerging and re-emerging pathogens in humans and animals [Virol J, 2015-12-22]Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
... Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and represents a potentially fatal disease of great global public health importance. As of March 26, 2020, the outbreak of COVID-19 has resulted in 462,801 confirmed cases and 20,839 deaths ...
Ref: The epidemiological and clinical features of COVID-19 and lessons from this global infectious public health event [J Infect, 2020-04-18]An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV),
... An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health ...
Ref: The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status [Mil Med Res, 2020]The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection
... The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute ...
Ref: COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses [J Adv Res, 2020-03-16]An outbreak of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus
... An outbreak of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) began in the city of Wuhan in China and has widely spread worldwide. Currently, it is vital to explore potential intermediate hosts of SARS-CoV-2 to control COVID-19 spread. Therefore, ...
Ref: Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak [Curr Biol, 2020]