Cuanto tiempo sobrevive el coronavirus fuera del cuerpo
(How long can the coronavirus live outside the body)
Primeras 5 respuestas:
-
An infected body is likelier to shed greater numbers of viral particles since the latter is more resistant to antimicrobial enzymes in body fluids.
-
Usually, viruses with pandemic potential like SARS-CoV-2 can survive for a long time on dry surfaces,
-
Severe Acute Respiratory Syndrome Coronavirus 2 can attack lung cells because there are many conserved receptor entries, namely Angiotensin Converting Enzyme-2.
-
The world is currently witnessing an outbreak of a new coronavirus spreading quickly across China and affecting at least 24 other countries.
-
The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onward virus transmission.
An infected body is likelier to shed greater numbers of viral particles since the latter is more resistant to antimicrobial enzymes in body fluids.
... expected to be highly resilient in saliva or other body fluids and outside the body. An infected body is likelier to shed greater numbers of viral particles since the latter is more resistant to antimicrobial enzymes in body fluids. These particles are also likelier to remain active longer. These factors could account for the ...
Ref: Shell disorder analysis predicts greater resilience of the SARS-CoV-2 (COVID-19) outside the body and in body fluids [Microb Pathog, 2020]Usually, viruses with pandemic potential like SARS-CoV-2 can survive for a long time on dry surfaces,
... Usually, viruses with pandemic potential like SARS-CoV-2 can survive for a long time on dry surfaces, resulting in a broad level of contamination in the environment. Therefore, improving the human behaviors to overcome the outbreak is urgently needed. We can speculate that human body fluids from ...
Ref: Body fluids may contribute to human-to-human transmission of severe acute respiratory syndrome coronavirus 2: evidence and practical experience [Chin Med, 2020-06-05]Severe Acute Respiratory Syndrome Coronavirus 2 can attack lung cells because there are many conserved receptor entries, namely Angiotensin Converting Enzyme-2.
... disease is indicated originating from animals traded in a live animal market in Wuhan, China. Severe Acute Respiratory Syndrome Coronavirus 2 can attack lung cells because there are many conserved receptor entries, namely Angiotensin Converting Enzyme-2. The presence of this virus in host cells will initiate various protective responses leading to ...
Ref: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response [Diabetes Metab Syndr, 2020]The world is currently witnessing an outbreak of a new coronavirus spreading quickly across China and affecting at least 24 other countries.
... The world is currently witnessing an outbreak of a new coronavirus spreading quickly across China and affecting at least 24 other countries. With almost 65,000 infected, a worldwide death toll of at least 1370 (as of 14 February 2020), and with the potential to affect up to two-thirds of the world population, ...
Ref: Rigidity of the Outer Shell Predicted by a Protein Intrinsic Disorder Model Sheds Light on the COVID-19 (Wuhan-2019-nCoV) Infectivity [Biomolecules, 2020-02-19]The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onward virus transmission.
... We prospectively assessed 49 coronavirus disease cases in Guangdong, China, to estimate the frequency and duration of detectable severe acute respiratory syndrome coronavirus 2 RNA in human body fluids. The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onward virus transmission. ...
Ref: Prolonged Persistence of SARS-CoV-2 RNA in Body Fluids. [Emerging infectious diseases, 2020-05-08]The ongoing global pandemic of coronavirus disease 2019 (COVID-19) has caused a huge number of human deaths.
... The ongoing global pandemic of coronavirus disease 2019 (COVID-19) has caused a huge number of human deaths. Currently, there are no specific drugs or vaccines available for this virus (SARS-CoV-2). The viral polymerase is a promising antiviral target. Here, we describe the near-atomic-resolution structure of the SARS-CoV-2 ...
Ref: Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2 [Cell Rep, 2020]As of March 10, 2020, the number of cases worldwide was 113,702.
... transmission of coronaviruses mainly occurs through saliva droplets and direct and indirect contact via surfaces. As of March 10, 2020, the number of cases worldwide was 113,702. Along with severe acute respiratory syndrome (SARS) and Middle Eastern respiratory syndrome (MERS), COVID-19 appears ...
Ref: Coronavirus: Update Related to the Current Outbreak of COVID-19 [Infect Dis Ther, 2020]As suddenly as SARS CoV emerged, it has seemingly gone quiescent.
As suddenly as SARS CoV emerged, it has seemingly gone quiescent. However another significant, and previously unknown or not described coronavirus respiratory disease has emerged.
Ref: EMERGING RESPIRATORY DISEASE - CORONAVIRUSES [Dis Mon, 2017-09-12]After approximately a month, the virus spread rapidly throughout mainland China.
... 2 (SARS-CoV-2) was first discovered from patients with pneumonia of unknown cause in Wuhan, China. After approximately a month, the virus spread rapidly throughout mainland China. 1 Later, cases of coronavirus disease 2019, also known as COVID-19, were also confirmed in ...
Ref: South Korea’s COVID-19 Infection Status: From the Perspective of Re-positive Test Results After Viral Clearance Evidenced by Negative Test Results [Disaster medicine and public health preparedness, 2020-05-22]More than 9000 healthcare workers have also been infected by 2019-nCoV.
... >2,622,571 confirmed cases of coronavirus disease 2019 (COVID-19) in >185 countries, and >182,359 deaths globally. More than 9000 healthcare workers have also been infected by 2019-nCoV. Prior to the present pandemic of COVID-19, there have been multiple large-scale epidemics and pandemics ...
Ref: Are dental schools adequately preparing dental students to face outbreaks of infectious diseases such as COVID-19? [J Dent Educ, 2020]At 2 days post-contact, SARS-CoV-2 was detected in all naive direct contact ferrets.
... ferrets shed virus in nasal washes, saliva, urine, and feces up to 8 days post-infection. At 2 days post-contact, SARS-CoV-2 was detected in all naive direct contact ferrets. Furthermore, a few naive indirect contact ferrets were positive for viral RNA, suggesting airborne transmission. ...
Ref: Infection and Rapid Transmission of SARS-CoV-2 in Ferrets [Cell Host Microbe, 2020]Coronavirus can last on for long durations on different metal surfaces, ranging from hours to days 13, 14 .
... Coronavirus can last on for long durations on different metal surfaces, ranging from hours to days 13, 14 . Recent studies show that the Coronavirus can last about three days on a plastic surface as well as on stainless steel surface, it can also sustain for a period of ...
Ref: Sustainability of Coronavirus on different surfaces [J Clin Exp Hepatol, 2020-05-06]this coronavirus (SARS-CoV-2) is abundantly present in nasopharyngeal and salivary secretions of affected patients,
... originated in bats and pangolins and later transmitted to humans. Once in the human body, this coronavirus (SARS-CoV-2) is abundantly present in nasopharyngeal and salivary secretions of affected patients, and its spread is predominantly thought to be respiratory droplet/contact in nature. Dental professionals, including ...
Ref: Coronavirus Disease 19 (COVID-19): Implications for Clinical Dental Care [J Endod, 2020]COVID-19 rapidly spread from a single Wuhan city to the entire country in just 30 days.
... In summary, COVID-19 is high in prevalence and population is generally susceptible to such virus, and COVID-19 rapidly spread from a single Wuhan city to the entire country in just 30 days. So that prompt measures should be taken to control the spread of the disease. ...
Ref: A review of the 2019 Novel Coronavirus (COVID-19) based on current evidence [Int J Antimicrob Agents, 2020-03-19]If a person died during the infectious period of COVID-19, the lungs and other organs may still contain live virus,
... small-particle aerosols, which is highly risky to personnel conducting an autopsy on a COVID-19 patient. If a person died during the infectious period of COVID-19, the lungs and other organs may still contain live virus, and additional respiratory protection is needed during aerosol-generating procedures such as the use of power ...
Ref: The craniotomy box: an innovative method of containing hazardous aerosols generated during skull saw use in autopsy on a COVID-19 body [Forensic Sci Med Pathol, 2020-06-04]A decade later in 2012, a couple of Saudi Arabian nationals were diagnosed to be infected with another coronavirus.
... then spread rapidly around the globe with more than 8000 infected persons and 776 deceases. A decade later in 2012, a couple of Saudi Arabian nationals were diagnosed to be infected with another coronavirus. The detected virus was confirmed as a member of coronaviruses and named as the Middle ...
Ref: COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses [J Adv Res, 2020-03-16]COVID-19 has caused over 133,000 deaths and there are over 2 million total confirmed cases as of April 15th, 2020.
... sequence identity to SARS-CoV, with 96% identity to a bat coronavirus at the whole-genome level. COVID-19 has caused over 133,000 deaths and there are over 2 million total confirmed cases as of April 15th, 2020. Current treatment plans are still under investigation due to a lack of understanding of COVID-19. ...
Ref: Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19 [Viruses, 2020]the virus does not have to stay long outside the body.
... efficiency in the spread among farm animals, as we have seen in TGEV, such that the virus does not have to stay long outside the body. The ability to stay longer in the environment could, however, provide advantages to a virus ...
Ref: Shell disorder analysis predicts greater resilience of the SARS-CoV-2 (COVID-19) outside the body and in body fluids [Microb Pathog, 2020-03-31]A total of 119 patients with COVID-19 were enrolled at Renmin Hospital of Wuhan University.
... the value of urine biochemical parameters in the prediction of the severity of COVID-19. Methods A total of 119 patients with COVID-19 were enrolled at Renmin Hospital of Wuhan University. According to the severity of COVID-19, the patients were divided into three groups (moderate 67, ...
Ref: The value of urine biochemical parameters in the prediction of the severity of coronavirus disease 2019 [Clin. chem. lab. med, 2020]With the spread of COVID-19 coronavirus, forehead temperature measurement is used widely to screen people for the illness.
... use. Two types of infrared thermometers are uses to measure body temperature: tympanic and forehead. With the spread of COVID-19 coronavirus, forehead temperature measurement is used widely to screen people for the illness. The performance of this type of device and the criteria for screening are worth studying. ...
Ref: Investigation of the Impact of Infrared Sensors on Core Body Temperature Monitoring by Comparing Measurement Sites [Clin. chem. lab. med, 2020]The SARS-CoV-2 can survive on various surfaces from a few hours to days.
... The SARS-CoV-2 can survive on various surfaces from a few hours to days. Therefore, 7 treatment room sanitation and disinfection with the appropriate disinfection guidelines is 8 needed to decrease contact transmission. 9 ...
Ref: Dental care and infection-control procedures during the COVID-19 pandemic: the experience in Taipei City Hospital, Taiwan [J Dent Sci, 2020-05-29]Will the virus replicate in other part of the body is not clear.
... Med Assoc like SARS, is ACE2. 18 However, the pathological changes of the disease and its pathogenesis in human is not clearly elucidated. Theoretically lungs are the major involved organ. Will the virus replicate in other part of the body is not clear. ...
Ref: cord_uid c4u0gxp5 Overview of The 2019 Novel Coronavirus (2019-n... c4u0gxp5 Overview of The 2019 Novel Coronavirus (2019-n... c4u0gxp5 The outbreak of COVID-19: An overview Name: title, dtype: object [J Dent Sci, cord_uid c4u0gxp5 2020-02-11 c4u0gxp5 2020 c4u0gxp5 2020-02-12 Name: publish_time, dtype: object]Coronaviruses can actively maintain their virulence at room temperature from 2 h up to 9 days.
... and aerosol mixed with patients" saliva and/ or blood, they can effectively help spread infection. Coronaviruses can actively maintain their virulence at room temperature from 2 h up to 9 days. Their activity at 50% humidity was significantly higher than 30%. Therefore, in the dental environment, ...
Ref: Being a front-line dentist during the Covid-19 pandemic: a literature review [Maxillofac Plast Reconstr Surg, 2020-04-24]The virus is then able to proliferate throughout the body, creating immune responses, and causing the person to become infected [69, 70] .
... and cellular membranes to fuse (Fig. 3 ). From there, the virus "hijacks" the cell; it integrates its RNA into the cell"s own replication machinery, facilitating propagation of the virus. The virus is then able to proliferate throughout the body, creating immune responses, and causing the person to become infected [69, 70] . ...
Ref: A Guide to COVID‐19: a global pandemic caused by the novel coronavirus SARS‐CoV‐2 [FEBS J, 2020-05-23]Patients with coronavirus disease 2019 (COVID-19) can unknowingly spread the virus to several people during the early subclinical period.
... BACKGROUND: Patients with coronavirus disease 2019 (COVID-19) can unknowingly spread the virus to several people during the early subclinical period. METHODS: We evaluated the viral dynamics in various body fluid specimens, such as nasopharyngeal swab, oropharyngeal swab, saliva, sputum, and urine specimens, of two patients with COVID-19 from hospital ...
Ref: Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva [J Korean Med Sci, 2020]Anti-coronavirus efficacy in vivo was confirmed by evaluating the time of recovery in canine coronavirus (CCV) infected dogs
... 48 hours post infection (p.i). The level of cell infection was determined by luciferase activity. Anti-coronavirus efficacy in vivo was confirmed by evaluating the time of recovery in canine coronavirus (CCV) infected dogs treated orally with 1mg/kg body weight indomethacin. Results We found that indomethacin has a directly ...
Ref: Indomethacin has a potent antiviral activity against SARS CoV-2 in vitro and canine coronavirus in vivo [bioRxiv, 2020-04-05]Three ferrets were sacrificed at 4, 8 and 12 dpi were
... SARS-CoV-2 infection in various organs, additional 9 ferrets were infected with SARS-CoV-2 by IN route. Three ferrets were sacrificed at 4, 8 and 12 dpi were and their lung, liver, spleen, kidney, and intestinal tissues were collected with individual scissors to ...
Ref: Infection and Rapid Transmission of SARS-CoV-2 in Ferrets [Cell Host Microbe, 2020-04-06]The emergence of the SARS-CoV-2 strain of the human coronavirus has thrown the world into the midst of a new pandemic.
... The emergence of the SARS-CoV-2 strain of the human coronavirus has thrown the world into the midst of a new pandemic. In the human body, the virus causes COVID-19, a disease characterized by shortness of breath, fever, and pneumonia, which can be fatal in vulnerable individuals. SARS-CoV-2 has characteristics of past ...
Ref: A Guide to COVID-19: a global pandemic caused by the novel coronavirus SARS-CoV-2 [FEBS j, 2020]The infection due to this virus spread exponentially throughout China and then spread across >205 nations, including the United States (US).
... the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), and the disease was called coronavirus disease-2019 (COVID-19). The infection due to this virus spread exponentially throughout China and then spread across >205 nations, including the United States (US). Gastrointestinal (GI) endoscopies are routinely performed in the US and globally. Previous reports of isolated ...
Ref: COVID-19 and gastrointestinal endoscopies: Current insights and emergent strategies [FEBS j, 2020]The possible person-to-person disease rapidly spread to many provinces in China as well as other countries.
... coronavirus (SARS-CoV) and uses the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), as SARS-CoV. The possible person-to-person disease rapidly spread to many provinces in China as well as other countries. Without a therapeutic vaccine or specific antiviral drugs, early detection and isolation become essential against ...
Ref: The genetic sequence, origin, and diagnosis of SARS-CoV-2 [Eur J Clin Microbiol Infect Dis, 2020-04-24]A highly virulent and pathogenic COVID-19 viral infection with incubation period ranging from two to fourteen days,
... and economical slowdown in each and every part of the world infecting nearly 200 countries. A highly virulent and pathogenic COVID-19 viral infection with incubation period ranging from two to fourteen days, transmitted by breathing of infected droplets or contact with infected droplets, belongs to the genus ...
Ref: COVID-19: a review. [Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2020-05-14]the virus has rapidly spread worldwide within 3 months.
... first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak was reported in December 2019, and the virus has rapidly spread worldwide within 3 months. 1 Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has become pandemic. Most COVID-19 patients show ...
Ref: Long‐term coexistence of SARS‐CoV‐2 with antibody response in COVID‐19 patients [J Med Virol, 2020-05-05]Since early December 2019, the novel coronavirus has caused an outbreak of pneumonia that has claimed over 2000 lives,
... Since early December 2019, the novel coronavirus has caused an outbreak of pneumonia that has claimed over 2000 lives, with more than 77,000 confirmed cases of infection by February 23, 2020 in China. [1] The World Health Organization (WHO) recently named the disease caused by this new coronavirus as ...
Ref: Voice from China: nomenclature of the novel coronavirus and related diseases [Chin Med J (Engl), 2020-05-05]Aerosolized SARS-CoV-2 viral particles remain viable for up to 3 hours,
... COVID-19 disease, over 55% of pediatric cases are present in asymptomatic or mildly symptomatic children. Aerosolized SARS-CoV-2 viral particles remain viable for up to 3 hours, raising concern about risk to healthcare workers during aerosol generating procedures (APGs) in the airway ...
Ref: Asymptomatic COVID-19 infection in a child with nasal foreign body [Int J Pediatr Otorhinolaryngol, 2020]Within 4 months, COVID-19 unexpectedly spread to 195 countries and regions,
... and declared as a Public Health Emergency of International Concern (PHEIC) on January 30, 2020. Within 4 months, COVID-19 unexpectedly spread to 195 countries and regions, led to more than 1 million confirmed cases in the world and was defined as ...
Ref: Comparison of SARS-CoV-2 infections among 3 species of non-human primates [bioRxiv, 2020-04-11]More than 9000 healthcare workers have also been infected by 2019‐nCoV.
... >2,622,571 confirmed cases of coronavirus disease 2019 (COVID‐19) in >185 countries, and >182,359 deaths globally. More than 9000 healthcare workers have also been infected by 2019‐nCoV. Prior to the present pandemic of COVID‐19, there have been multiple large‐scale epidemics and pandemics ...
Ref: Are dental schools adequately preparing dental students to face outbreaks of infectious diseases such as COVID‐19? [J Dent Educ, 2020-05-11]The outbreak of the coronavirus disease 2019 (COVID19) pandemic has become the biggest challenge for the whole human community since many years.
... The outbreak of the coronavirus disease 2019 (COVID19) pandemic has become the biggest challenge for the whole human community since many years. It seems that the proper identification of all people infected with severe acute respiratory syndrome coronavirus 2 (SARSCoV2) is the best strategy to limit the transmission. However, in a significant ...
Ref: Addressing multiple gastroenterological aspects of coronavirus disease 2019 [Pol Arch Intern Med, 2020]Over the next several months, international travel allowed for the rapid spread of >8,000 cases over three continents.
... Cases of SARS were first identified from Guangdong Province in southern China in November 2002. Over the next several months, international travel allowed for the rapid spread of >8,000 cases over three continents. The economic and psychological impact of this mysterious illness was profound. In order to better ...
Ref: Severe acute respiratory syndrome. [Connecticut medicine, 2004]Being a 'trauma of mankind' epidemics have been a major subject of historical research for a long time and regarding every historical period.
... This paper is part of Forum COVID-19: Perspectives in the Humanities and Social Sciences. Being a "trauma of mankind" epidemics have been a major subject of historical research for a long time and regarding every historical period. Recurring to the concept of Rudolf Schlögl ("Vergesellschaftung unter Anwesenden") my proposal is to research epidemics ...
Ref: Vergesellschaftung unter Ansteckenden für eine Körpergeschichte der Seuche./ [Infectious Socialization-The History of Contagious Bodies] [NTM, 2020]such that the virus does not have to stay long outside the body.
... provide greater efficiency in the spread among farm animals, as we have seen in TGEV, such that the virus does not have to stay long outside the body. The ability to stay longer in the environment could, however, provide advantages to a virus ...
Ref: Shell disorder analysis predicts greater resilience of the SARS-CoV-2 (COVID-19) outside the body and in body fluids [Microb Pathog, 2020-03-31]Since December 2019, the newly discovered coronavirus (2019-nCov) has caused the outbreak of pneumonia in Wuhan and throughout China.
... Since December 2019, the newly discovered coronavirus (2019-nCov) has caused the outbreak of pneumonia in Wuhan and throughout China. 2019-nCov enters host cells through human cell receptor ACE2, the same with SARS-CoV, but with higher binding affinity 61 . The rapidly increasing number of cases and evidence of human-to-human ...
Ref: Transmission routes of 2019-nCoV and controls in dental practice [Int J Oral Sci, 2020-03-03]even if the virus does enter the aquatic environment, enveloped viruses, which include coronaviruses, are believed to have a short survival rate in such waters
... the reduction in viability of viruses, there is still a possibility of the virus remaining in the WWTP effluent (Wigginton et al., 2015) . However, even if the virus does enter the aquatic environment, enveloped viruses, which include coronaviruses, are believed to have a short survival rate in such waters (Wigginton et al., 2015) . ...
Ref: Recreational waters – A potential transmission route for SARS-CoV-2 to humans? [Sci Total Environ, 2020-10-20]The infection spread very quickly throughout China and over 100 countries.
... acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caused an outbreak of coronavirus disease in Wuhan, China. The infection spread very quickly throughout China and over 100 countries. To date, over 100,000 cases have been confirmed worldwide and at least 3000 patients have ...
Ref: Do children need a longer time to shed SARS-CoV-2 in stool than adults? [J Microbiol Immunol Infect, 2020-03-19]On day 14 post viral inoculation, six animals were anesthetized, bled and necropsied.
... Viral genomic RNA in these samples was quantified by RT-qPCR using virus-specific primers and probes. On day 14 post viral inoculation, six animals were anesthetized, bled and necropsied. After gross lesions were recorded, tissue samples were harvested for analysis of viral loads and ...
Ref: Susceptibility of tree shrew to SARS-CoV-2 infection [bioRxiv, 2020-04-30]TGEV could move rapidly among farm pigs to quickly devastate the farming community if not controlled early [5] [6] [7] .
... so in the case of TGEV (transmissible gastroenteritis virus) and PEDV (porcine epidemic diarrhea virus). TGEV could move rapidly among farm pigs to quickly devastate the farming community if not controlled early [5] [6] [7] . Our analysis reveals that TGEV is of category C (higher fecal-oral, lower respiratory transmission potentials) ...
Ref: Shell disorder analysis predicts greater resilience of the SARS-CoV-2 (COVID-19) outside the body and in body fluids [Microb Pathog, 2020-03-31]Last but not least, currently available and possible future therapeutic and diagnostic options are briefly commented on.
... beginning from the virus, its transmission, and mechanisms of entry into the human body, through the pathological effects on the cellular level, up to immunological reaction, systemic and organ presentation. Last but not least, currently available and possible future therapeutic and diagnostic options are briefly commented on. ...
Ref: COVID-19 - toward a comprehensive understanding of the disease. [Cardiology journal, 2020-05-07]Hospital admission and general treatments should be started as soon as possible in symptomatic COVID-19 patients, especially male patients.
... were independent risk factors for prolonged SARS-CoV-2 RNA shedding. CONCLUSIONS: Male sex, delayed admission to hospital after illness onset, and invasive mechanical ventilation were associated with prolonged SARS-CoV-2 RNA shedding. Hospital admission and general treatments should be started as soon as possible in symptomatic COVID-19 patients, especially male patients. ...
Ref: Factors associated with prolonged viral RNA shedding in patients with COVID-19 [Clin. infect. dis, 2020]However, researchers are yet to establish whether SARS-CoV-2 can directly enter the salivary glands.
... coronavirus 2 (SARS-CoV-2) in saliva with a viral load that lasts for a long period. However, researchers are yet to establish whether SARS-CoV-2 can directly enter the salivary glands. Therefore, this study aimed to assess the presence of angiotensin-converting enzyme 2 (ACE2)/transmembrane serine proteases ...
Ref: Systematic analysis of ACE2 and TMPRSS2 expression in salivary glands reveals underlying transmission mechanism caused by SARS-CoV-2 [J. med. virol, 2020]Five days later, he was found dead at home during a police inspection.
... show severe respiratory symptoms. He received pain medication and a cough suppressant as a reliever. Five days later, he was found dead at home during a police inspection. He had been last seen alive just 24 hours prior to his discovery by the ...
Ref: Gross and histopathological pulmonary findings in a COVID-19 associated death during self-isolation [Int J Legal Med, 2020-06-05]During this pandemic clinical trial accrual to NCI studies has fallen dramatically.
... (SARS-CoV-2), is a global health threat.1 Cancer patients are one of the most vulnerable populations. During this pandemic clinical trial accrual to NCI studies has fallen dramatically. Investigators quickly turned to regulatory bodies to simplify treatment schedules, facilitate telemedicine and to decrease ...
Ref: The World of Clinical Trial Development Post-Covid-19: Lessons Learned from a Global Pandemic. [Clinical cancer research : an official journal of the American Association for Cancer Research, 2020-06-05]We searched five general, three Chinese and four coronavirus disease (COVID-19)-specific electronic databases.
... scope and assess the effects of specific strategies for the management of the bodies. METHODS: We searched five general, three Chinese and four coronavirus disease (COVID-19)-specific electronic databases. We searched registries of clinical trials, websites of governmental and other relevant organisations, reference lists ...
Ref: Safe management of bodies of deceased persons with suspected or confirmed COVID-19: a rapid systematic review [Clinical cancer research : an official journal of the American Association for Cancer Research, 2020]An infected body is likelier to shed greater numbers of viral particles
... expected to be highly resilient in saliva or other body fluids and outside the body. An infected body is likelier to shed greater numbers of viral particles since the latter is more resistant to antimicrobial enzymes in body fluids. These particles are ...
Ref: Shell disorder analysis predicts greater resilience of the SARS-CoV-2 (COVID-19) outside the body and in body fluids [Microb Pathog, 2020]The emerging virus, COVID-19, has caused a massive outbreak worldwide.
... Backgrounds: The emerging virus, COVID-19, has caused a massive outbreak worldwide. Based on the publicly available contact-tracing data, we identified 337 transmission chains from 10 provinces in China and estimated the serial interval (SI) and generation interval (GI) of COVID-19 ...
Ref: ‘We will have many body bags.’ WHO chief responds to Trump’s criticisms [Science, 2020]In the nearly 4 months since the outbreak was discovered, more than a million people have been infected worldwide.
... of new cases by reducing the crowd gathering, virus elimination, personal protection and other work. In the nearly 4 months since the outbreak was discovered, more than a million people have been infected worldwide. Most countries around the world are testing their populations for potential cases, isolating them as ...
Ref: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a review [Mol Cancer, 2020-06-02]In December 2019, 41 cases of unexplained pneumonia were clustered in Wuhan, Hubei Province, China.
... In December 2019, 41 cases of unexplained pneumonia were clustered in Wuhan, Hubei Province, China. Most of the infected people were confirmed to be related to the South China Seafood Market. ...
Ref: Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS‐CoV‐2 infection [J Med Virol, 2020-03-12]Methods SARS CoV-2 pseudovirus-infected African green monkey kidney VERO E6 cells
... the ability to inhibit the replication of several unrelated DNA and RNA viruses, including SARS-CoV. Methods SARS CoV-2 pseudovirus-infected African green monkey kidney VERO E6 cells treated with different concentrations of indomethacin or aspirin at 48 hours post infection (p.i). The ...
Ref: Indomethacin has a potent antiviral activity against SARS CoV-2 in vitro and canine coronavirus in vivo [bioRxiv, 2020-04-05]The current epidemic of COVID-19 (coronavirus) has been declared by WHO as a global epidemic.
... The current epidemic of COVID-19 (coronavirus) has been declared by WHO as a global epidemic. This COVID-19 epidemic is somewhat similar to the previous severe acute respiratory syndrome (SARS-CoV-2 or SARS; [2002] [2003] and Middle East respiratory syndrome (MERS; 2012-ongoing) outbreaks. All these infections could ...
Ref: Can Bioactive Lipids Inactivate Coronavirus (COVID-19)? [Arch Med Res, 2020-03-27]the virus could persist for a longer period of time in the male reproductive system compared with other body fluids, rendering the testis a potential viral reservoir.
... SARS-CoV-2, and also by those previously infected, even after the signs and symptoms have resolved. It is recommended to avoid possible transfection by refraining from sexual relations without protection, as the virus could persist for a longer period of time in the male reproductive system compared with other body fluids, rendering the testis a potential viral reservoir. ...
Ref: SARS-CoV-2 and the testis: similarity with other viruses and routes of infection [Reprod Biomed Online, 2020-04-17]The outbreak of coronavirus disease 2019 (COVID-19) pandemic has become the biggest challenge for the whole human community since many years.
... The outbreak of coronavirus disease 2019 (COVID-19) pandemic has become the biggest challenge for the whole human community since many years. It seems that the appropriate identification of all people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the best strategy to limit COVID-19 transmission. However, in a significant ...
Ref: Addressing multiple gastroenterological aspects of COVID-19. [Polish archives of internal medicine, 2020-05-01]By Feb 28, 2020, all patients were cured.
... and six (17%) needed oxygen inhalation. Mean time in hospital was 14 (SD 3) days. By Feb 28, 2020, all patients were cured. INTERPRETATION: Although all paediatric patients in our cohort had mild or moderate type of COVID-19, ...
Ref: Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study [Lancet Infect Dis, 2020]Mortality from coronavirus disease 2019 (COVID-19) is increased in COPD patients.
... OBJECTIVE: Mortality from coronavirus disease 2019 (COVID-19) is increased in COPD patients. Furthermore, higher body mass index (BMI) is related to severe disease. SARS-CoV-2 utilises angiotensin converting enzyme 2 (ACE2) to gain cellular entry. METHODS: We have investigated whether ACE2 bronchial ...
Ref: Increased ACE2 Expression in the Bronchial Epithelium of COPD Patients who are Overweight [Obesity (Silver Spring), 2020]infects the human body
... at a dreadfully fast rate. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the pathogen of COVID-19, infects the human body using angiotensin-converting enzyme 2 (ACE2) as a receptor identical to the severe acute respiratory syndrome ...
Ref: COVID-19 preclinical models: human angiotensin-converting enzyme 2 transgenic mice [Hum Genomics, 2020]There remains a challenge to determine the extent to which neurological abnormalities in COVID-19 are caused by SARS-Cov2 itself,
... patients with coronavirus disease-19 (COVID-19) which is caused by acute respiratory syndrome coronavirus 2 (SARS-Cov2). There remains a challenge to determine the extent to which neurological abnormalities in COVID-19 are caused by SARS-Cov2 itself, the exaggerated cytokine response it triggers, and/or the resulting hypercoagulapathy and formation of blood clots ...
Ref: Neurobiology of COVID-19. [Journal of Alzheimer's disease : JAD, 2020-06-08]The patient was confirmed as SARS-CoV-2 infection on the 4th day after surgery
... infection complicated with esophageal foreign body perforation with no significant changes in the lung CT The patient was confirmed as SARS-CoV-2 infection on the 4th day after surgery and then was transferred into the Department of Infectious Disease in our hospital for treatment ...
Ref: Surgical treatment of latent infection of 2019 novel coronavirus (SARS-CoV-2) with esophageal foreign body perforation: A case report [Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2020]METHODS: We searched five general, three Chinese and four coronavirus disease (COVID-19)-specific electronic databases.
... to scope and assess the effects of specific strategies for the management of the bodies. METHODS: We searched five general, three Chinese and four coronavirus disease (COVID-19)-specific electronic databases. We searched registries of clinical trials, websites of governmental and other relevant organisations, reference lists ...
Ref: Safe management of bodies of deceased persons with suspected or confirmed COVID-19: a rapid systematic review [Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2020]SARS-CoV-2 has spread rapidly since its outbreak
SARS-CoV-2 has spread rapidly since its outbreak and has now posed a risk to
Ref: Highly pathogenic coronaviruses: thrusting vaccine development in the spotlight [Acta Pharm Sin B, 2020-05-30]to estimate the frequency and duration of detectable severe acute respiratory syndrome coronavirus 2 RNA in human body fluids.
... We prospectively assessed 49 coronavirus disease cases in Guangdong, China, to estimate the frequency and duration of detectable severe acute respiratory syndrome coronavirus 2 RNA in human body fluids. The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onward virus ...
Ref: Prolonged Persistence of SARS-CoV-2 RNA in Body Fluids. [Emerging infectious diseases, 2020-05-08]This therapy seems to be able to give results at the beginning of therapy, that is 14 days after being diagnosed,
... (such as MERS-CoV) have commonly used combinations of interferon-α combined with ribavirin [40, 41] . This therapy seems to be able to give results at the beginning of therapy, that is 14 days after being diagnosed, but this effect disappears when entering day 28. Furthermore, Loutfy et al. found that the ...
Ref: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response [Diabetes Metab Syndr, 2020-04-18]These particles are also likelier to remain active longer.
... of viral particles since the latter is more resistant to antimicrobial enzymes in body fluids. These particles are also likelier to remain active longer. These factors could account for the greater contagiousness of the SARS-CoV-2 and have implications for ...
Ref: Shell disorder analysis predicts greater resilience of the SARS-CoV-2 (COVID-19) outside the body and in body fluids [Microb Pathog, 2020]Over the same time period, it has claimed the lives of 165 000 individuals.
... desirable and undesirable effects of each management strategy, and contextual factors that require evidence. worldwide. Over the same time period, it has claimed the lives of 165 000 individuals. 1 More concerning than the absolute number of deaths is their rate of increase. The ...
Ref: Safe management of bodies of deceased persons with suspected or confirmed COVID-19: a rapid systematic review [BMJ Glob Health, 2020-05-14]The mechanism of AdE has not been confirmed for coronavirus in humans (90) .
... with the virus, they will actually help it enter the cells and cause infection. AdE has been described in many viral infections (influenza, Dengue, Zika, etc.), but also in coronaviruses. The mechanism of AdE has not been confirmed for coronavirus in humans (90) . ...
Ref: Towards effective COVID-19 vaccines: Updates, perspectives and challenges (Review) [Int J Mol Med, 2020-05-06]The world has given an outbreak alarm in the last two decades, with different members of the coronavirus family infecting people at different times.
... The world has given an outbreak alarm in the last two decades, with different members of the coronavirus family infecting people at different times. The spread of the SARS-CoV-2 virus, which last appeared in December 2019 in China and spread rapidly to all over the world, has led the scientific world to studies on ...
Ref: Immune Responses to SARS-CoV, MERS-CoV and SARS-CoV-2. [Advances in experimental medicine and biology, 2020-06-09]the rapid virus spread into human body, remain unresolved.
... underlining the molecular recognition of SARS-CoV-2 to the angiotensin-converting enzyme 2 (ACE2) receptor and, thus, the rapid virus spread into human body, remain unresolved. Here, multi-microsecond-long molecular dynamics simulations enabled us to unprecedentedly dissect the key molecular traits liable ...
Ref: Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations [J Phys Chem Lett, 2020]Despite all these efforts, the development of a suitable and effective drug(s) against SARS-CoV-19 will take time.
... is being tested on the basis of its capacity to inhibit ACE2-mediated endocytosis. JAK inhibitor, Jakafi (ruxolitinib), is now under clinical trials (combined with mesenchymal stem cell infusion) for COVID-19. Despite all these efforts, the development of a suitable and effective drug(s) against SARS-CoV-19 will take time. ...
Ref: Can Bioactive Lipids Inactivate Coronavirus (COVID-19)? [Arch Med Res, 2020-03-27]After 6 years, the humoral immunity continuously decreased and eventually disappeared in most infected individuals.
... The protective immunity by the time in patients after SARS-CoV natural infection was observed. After 6 years, the humoral immunity continuously decreased and eventually disappeared in most infected individuals. The IgG Ab could be an indicator of neutralizing Ab for the humoral response to SARS-CoV ...
Ref: Coronaviruses pandemics: Can neutralizing antibodies help? [Life Sci, 2020-05-22]COVID-19 was declared a global pandemic on March 11, 2020.
... COVID-19 was declared a global pandemic on March 11, 2020. Scientists and clinicians must acknowledge that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to attack the human body in multiple ways simultaneously and exploit any weaknesses of ...
Ref: Potential Neuroinvasive Pathways of SARS-CoV-2: Deciphering the Spectrum of Neurological Deficit Seen in Coronavirus Disease 2019 (COVID-19) [J. med. virol, 2020]In order to avoid SARS-CoV-2 infection, he stayed at home except for a 1-day walk in the town district.
... had no exposure to marketplaces, live animals, known sick people or access to healthcare facilities. In order to avoid SARS-CoV-2 infection, he stayed at home except for a 1-day walk in the town district. His close contacts were the three members of the Chinese family hosting him, who are ...
Ref: Coronavirus disease (COVID-19) in a paucisymptomatic patient: epidemiological and clinical challenge in settings with limited community transmission, Italy, February 2020 [Euro Surveill, 2020-03-19]SARS CoV can retain its infectivity up to 2 weeks at low temperature and low humidity environment,
... well ventilated and these may well have reduced virus survival and this reduced nosocomial transmission. SARS CoV can retain its infectivity up to 2 weeks at low temperature and low humidity environment, which might facilitate the virus transmission in community as in Hong Kong which locates in ...
Ref: The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus [Adv Virol, 2011-10-01]On March 7, all the mobile cabin hospitals in Wuhan discharged the patients.
... Fortunately, until recently, China is successful in bringing the epidemic under control. On March 7, all the mobile cabin hospitals in Wuhan discharged the patients. Most remarkably, according to the official news in China on March 6, no COVID-19 infection was reported among ...
Ref: Body fluids may contribute to human-to-human transmission of severe acute respiratory syndrome coronavirus 2: evidence and practical experience [Chin Med, 2020-06-05]These studies are in progress, but it requires months to years to develop the vaccines for SARS-CoV-2.
... coronavirus outbreaks. There are several vaccination strategies against SARS-CoV, MERS-CoV tested in animals, including a liveattenuated virus, viral vectors, inactivated virus, subunit vaccines, recombinant DNA, and proteins vaccines [73] . These studies are in progress, but it requires months to years to develop the vaccines for SARS-CoV-2. ...
Ref: Molecular immune pathogenesis and diagnosis of COVID-19 [J Pharm Anal, 2020-03-05]Up to the end of April 2020, at least 115 SARS-CoV-2 vaccine projects have been announced to be in development,
... a race to pursue different types of vaccines to prevent infection with this novel virus. Up to the end of April 2020, at least 115 SARS-CoV-2 vaccine projects have been announced to be in development, including vectored vaccines, oral vaccines, subunit vaccines, inactivated vaccines, peptide-based vaccines, nucleotide-based vaccine, etc. Several ...
Ref: mRNA Vaccines: Possible Tools to Combat SARS-CoV-2 [Virol Sin, 2020-06-10]Specimens from sputum, stool, and nasopharyngeal swabs were collected throughout the illness from 30 January 2020 to 5 April 2020.
... Specimens from sputum, stool, and nasopharyngeal swabs were collected throughout the illness from 30 January 2020 to 5 April 2020. Viral RNA was extracted from clinical specimens, and real-time reverse-transcription polymerase chain reaction was performed to test the presence of SARS-CoV-2 using "Novel (Table 1) . No SARS-CoV-2-specific IgG and ...
Ref: Long‐term coexistence of SARS‐CoV‐2 with antibody response in COVID‐19 patients [J Med Virol, 2020-05-05]Nearly 20% of hospitalized patients with COVID-19 have evidence of cardiac damage [17] .
... suggest that SARS-CoV-2 may lead to damage to other organs including the heart and brain. Nearly 20% of hospitalized patients with COVID-19 have evidence of cardiac damage [17] . Furthermore, neurologic symptoms have been reported in patients and infection of SARS-CoV-2 reported in the ...
Ref: Hot Topic Commentary on COVID-19 [Curr Pharmacol Rep, 2020-05-11]After SARS outbreak, a new coronavirus strain called MERS-CoV is now going to cause another outbreak [4] .
... the first two strains were not so much deadly but the other members were pathogenic. After SARS outbreak, a new coronavirus strain called MERS-CoV is now going to cause another outbreak [4] . The cell tropism and cellular receptor of the six types of coronaviruses are not similar ...
Ref: A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design [BMC Bioinformatics, 2014-05-29]The virus spread rapidly and public health authorities in China initiated a containment effort.
... had been associated with the Wuhan Wholefood market, where seafood and live animals are sold. The virus spread rapidly and public health authorities in China initiated a containment effort. However, by that time, travelers had carried the virus to many countries, sparking memories of ...
Ref: SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far [BMC Bioinformatics, 2020]If coronavirus outbreaks recur, we need to ensure that the infrastructure remains in place for the molecular farming community to meet future pandemics.
If coronavirus outbreaks recur, we need to ensure that the infrastructure remains in place for the molecular farming community to meet future pandemics.
Ref: Potential applications of plant biotechnology against SARS-CoV-2 [Trends Plant Sci, 2020-04-24]SARS-CoV-2 may survive for a long time or replicate in the conjunctiva, after conjunctivitis signs vanished.
... and that there is a low risk of coronavirus spreading through tears [22] , nevertheless SARS-CoV-2 may survive for a long time or replicate in the conjunctiva, after conjunctivitis signs vanished. Therefore, eye protection (protective goggles alone or in association with face shield) are necessary to ...
Ref: The Ocular Surface and the Coronavirus Disease 2019: Does a Dual ‘Ocular Route’ Exist? [J Clin Med, 2020-04-28]In the meantime, SARS has been recognized in patients on all five continents.
... is an emerging disease, which was first recognized in Guangdong Province, China, in November 2002. In the meantime, SARS has been recognized in patients on all five continents. A novel coronavirus, which is not related to the hitherto known coronaviruses, has been proven ...
Ref: [SARS, possible zoonosis in the area of conflict of pathogenic coronaviruses of animals]. [Schweizer Archiv fur Tierheilkunde, 2003]In December 2019, an outbreak of a novel coronavirus disease (COVID-19) emerged in Wuhan, China,
... In December 2019, an outbreak of a novel coronavirus disease (COVID-19) emerged in Wuhan, China, and has quickly spread throughout the world. 1 COVID-19 is a highly contagious disease capable of progression to acute respiratory distress syndrome and even death. 1 The infectious agent of ...
Ref: Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease [Br J Ophthalmol, 2020-04-07]SARS-CoV-2-infected ferrets shed virus in nasal washes, saliva, urine, and feces up to 8 days post-infection.
... disease. SARS-CoV-2-infected ferrets exhibit elevated body temperatures and virus replication. Although fatalities were not observed, SARS-CoV-2-infected ferrets shed virus in nasal washes, saliva, urine, and feces up to 8 days post-infection. At 2 days post-contact, SARS-CoV-2 was detected in all naive direct contact ferrets. Furthermore, a ...
Ref: Infection and Rapid Transmission of SARS-CoV-2 in Ferrets [Cell Host Microbe, 2020]The rapid spread of severe acute respiratory coronavirus syndrome 2 (SARS-CoV-2) in the population and throughout the cells within our body
... The rapid spread of severe acute respiratory coronavirus syndrome 2 (SARS-CoV-2) in the population and throughout the cells within our body has been developing Another major cycle of coronavirus disease 2019 (COVID-19), which is expected in the coming fall, could be even more severe than the current one Therefore, effective countermeasures ...
Ref: Empirical Treatment and Prevention of COVID-19 [Infection & chemotherapy, 2020]SARS-CoV persistence in body fluids (stools and serum) was up to 96 hours.
... infected individuals (Wigginton et al., 2015) . For instance, Wang et al. (2005c) observed that SARS-CoV persistence in body fluids (stools and serum) was up to 96 hours. Similarly the RIVM (Rijksinstituut voor Volksgezondheid en Milieu, Holland)some studies recently reported traces of the ...
Ref: Current emerging SARS-CoV-2 pandemic: potential direct/indirect negative impacts of virus persistence and related therapeutic drugs on the aquatic compartments [Environ Res, 2020-06-10]SARS CoV-2 pseudovirus-infected African green monkey kidney VERO E6 cells
... ability to inhibit the replication of several unrelated DNA and RNA viruses, including SARS-CoV. Methods SARS CoV-2 pseudovirus-infected African green monkey kidney VERO E6 cells treated with different concentrations of indomethacin or aspirin at 48 hours post infection (p.i). The ...
Ref: Indomethacin has a potent antiviral activity against SARS CoV-2 in vitro and canine coronavirus in vivo [bioRxiv, 2020-04-05]The virus persists in the oviduct and as a result, is reexcreted at the onset of egg laying [57] .
... IBV can also replicate in the kidneys where it causes nephritis, in the oviduct, and along most of the alimentary tract. The intestinal infection generally has no clinically obvious effect. The virus persists in the oviduct and as a result, is reexcreted at the onset of egg laying [57] . ...
Ref: Vaccination Against Coronaviruses In Domestic Animals [Vaccine, 2020-06-10]Five days before that onset, patients 2 and 3 came from Wuhan, the focus of the 2019-nCov epidemic.
... had not left his apartment for at least 2 weeks before onset of his illness. Five days before that onset, patients 2 and 3 came from Wuhan, the focus of the 2019-nCov epidemic. It was confirmed that patients 2, 3, and 4 had not any symptoms for at ...
Ref: A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period [J Infect Dis, 2020-02-18]SARS-CoV-2 could present an asymptomatic incubation period for infected individuals that varies from 5 or 6 to 14 days.
... with hands which have come into contact with contaminated surfaces or airborne particles [4] . SARS-CoV-2 could present an asymptomatic incubation period for infected individuals that varies from 5 or 6 to 14 days. Backer has reported that virus identification in human respiratory epithelial cells could be positive about ...
Ref: The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) in Dentistry. Management of Biological Risk in Dental Practice [Int J Environ Res Public Health, 2020-04-28]throughout the cells within our body has been developing.
... The rapid spread of severe acute respiratory coronavirus syndrome 2 (SARS-CoV-2) in the population and throughout the cells within our body has been developing. Another major cycle of coronavirus disease 2019 (COVID-19), which is expected in the coming fall, ...
Ref: Empirical Treatment and Prevention of COVID-19. [Infection & chemotherapy, 2020-06-01]its reach can extend to many organs
... wrought by the coronavirus as it tears through the body They are realizing that although the lungs are ground zero, its reach can extend to many organs including the heart and blood vessels, kidneys, gut, and brain ...
Ref: How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes [Science, 2020]This study reports the surgical treatment of a female patient at age of 64 years
... This study reports the surgical treatment of a female patient at age of 64 years with novel coronavirus (SARS-CoV-2) latent infection complicated with esophageal foreign body perforation with no significant changes in the lung CT The patient was confirmed as SARS-CoV-2 infection on the 4th ...
Ref: Surgical treatment of latent infection of 2019 novel coronavirus (SARS-CoV-2) with esophageal foreign body perforation: A case report [Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2020]The genetically diverse Orthocoronavirinae (coronavirus, CoV) family circulates 45 in many avian and mammalian species.
... The genetically diverse Orthocoronavirinae (coronavirus, CoV) family circulates 45 in many avian and mammalian species. Phylogenetically, CoVs are divided into 4 46 genera: alpha (group 1), beta (group 2), gamma (group 3) and delta (group 4). Three 47 expressing nanoluciferase (MERS-nLUC) 15 , we measured ...
Ref: An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus [bioRxiv, 2020-03-20]