¿Son probables las complicaciones cardíacas en pacientes con COVID-19?

(Are cardiac complications likely in patients with covid-19?)


Primeras 5 respuestas:

  1. COVID-19 patients with basic cardiovascular disease are more likely to progress to the severe conditions and even death.

  2. Careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with COVID-19.

  3. Many patients with COVID-19 experienced acute myocardial injury as evident by an increase in high-sensitivity cardiac troponin I levels (6) .

  4. The cardiac manifestations of COVID-19 include myocarditis, arrhythmia, and myocardial infarction.

  5. Patients with cardiovascular disease are more likely to be infected with SARS-CoV-2 and they are more likely to develop severe symptoms.



COVID-19 patients with basic cardiovascular disease are more likely to progress to the severe conditions and even death.

... COVID-19 patients with basic cardiovascular disease are more likely to progress to the severe conditions and even death. Hence, we further studied the expression of ACE2 in patients with heart muscle disease. RNA sequencing revealed that myocardial ACE2 expression was significantly increased in patients with heart failure ( ...

Ref: The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2 [Cardiovasc Res, 2020-03-30]


Careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with COVID-19.

... severity of the disease. It was found that higher concentration in venous blood of CK-MB, MYO, ultra-TnI, and NT-proBNP were associated with the severity and case fatality rate of COVID-19. Careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with COVID-19. ...

Ref: Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China [J Med Virol, 2020]


Many patients with COVID-19 experienced acute myocardial injury as evident by an increase in high-sensitivity cardiac troponin I levels (6) .

... Many patients with COVID-19 experienced acute myocardial injury as evident by an increase in high-sensitivity cardiac troponin I levels (6) . This could be secondary to direct cardiotoxicity or could represent type II myocardial injury in the context of supply-demand mismatch. Moreover, cardiac biomarker levels were significantly higher in patients admitted ...

Ref: The Novel Coronavirus Disease (COVID-19) Threat for Patients with Cardiovascular Disease and Cancer [JACC CardioOncol, 2020-04-10]


The cardiac manifestations of COVID-19 include myocarditis, arrhythmia, and myocardial infarction.

... with pediatric and congenital heart disease may likewise be at increased risk for severe infection. The cardiac manifestations of COVID-19 include myocarditis, arrhythmia, and myocardial infarction. Importantly, the pandemic has stretched healthcare systems and many care team members are at risk ...

Ref: Coronavirus Disease 2019 (COVID-19) Pandemic Implications in Pediatric and Adult Congenital Heart Disease [J Am Heart Assoc, 2020]


Patients with cardiovascular disease are more likely to be infected with SARS-CoV-2 and they are more likely to develop severe symptoms.

... of the virus. Disruption of this receptor leads to cardiomyopathy, cardiac dysfunction, and heart failure. Patients with cardiovascular disease are more likely to be infected with SARS-CoV-2 and they are more likely to develop severe symptoms. Hypertension, arrhythmia, cardiomyopathy and coronary heart disease are amongst major cardiovascular disease comorbidities seen in ...

Ref: Myocardial injury and COVID-19: Possible mechanisms [Life Sci, 2020]


However, their cardiotoxicity which include arrhythmia, heart failure, myocardial disorder may be severe and irreversible 64 .

... on cardiovascular system. Macrolides ( for example azithromycin) 61 Chloroquine/Hydroxychloroquine, which is an old drug for malaria, has been confirmed to be effective in patients with COVID-19 62, 63 . However, their cardiotoxicity which include arrhythmia, heart failure, myocardial disorder may be severe and irreversible 64 . ...

Ref: Coronavirus disease 2019 (COVID-19) and cardiovascular complications [J Cardiothorac Vasc Anesth, 2020-04-30]


The patient did not show any respiratory involvement during the clinical course.

... magnetic resonance imaging, the week after onset of fever and dry cough due to COVID-19. The patient did not show any respiratory involvement during the clinical course. Exposure: Cardiac involvement with COVID-19. Main Outcomes and Measures: Detection of cardiac involvement with an ...

Ref: Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) [JAMA cardiol. (Online), 2020]


COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure.

... The patient died of aggravation of secondary infection on the 33rd day of hospitalization. CONCLUSION: COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. This is the first report of COVID-19 complicated with fulminant myocarditis. The mechanism of cardiac ...

Ref: First case of COVID-19 complicated with fulminant myocarditis: a case report and insights [Infection, 2020-04-10]


One of the life­threatening cardiac manifestations is coronavirus fulminant myocarditis, which may also occur without accompanying symptoms of pulmonary involvement.

... pro-B­type natriuretic peptide concentration, and increased cardiac troponin level was found in 10% of patients. One of the life­threatening cardiac manifestations is coronavirus fulminant myocarditis, which may also occur without accompanying symptoms of pulmonary involvement. Early recognition and treatment is crucial in these cases. So far, data on the incidence ...

Ref: What should a cardiologist know about coronavirus disease 2019? [Kardiol Pol, 2020]


The cardiac manifestations of COVID-19 include myocarditis, arrhythmia and myocardial infarction.

... pediatric and congenital heart disease (CHD) may likewise be at increased risk for severe infection. The cardiac manifestations of COVID-19 include myocarditis, arrhythmia and myocardial infarction. Importantly, the pandemic has stretched health care systems and many care team members are at ...

Ref: Coronavirus Disease 2019 (COVID-19) Pandemic Implications in Pediatric and Adult Congenital Heart Disease. [Journal of the American Heart Association, 2020-05-22]


Cardiac injury is a prevalent complication of severe patients, exacerbating the disease severity in coronavirus disease 2019 (COVID-19) patients.

... to patients infected by SARS-CoV and MERS-CoV, and nearly 20% of patients developed severe condition. Cardiac injury is a prevalent complication of severe patients, exacerbating the disease severity in coronavirus disease 2019 (COVID-19) patients. Angiotensin-converting enzyme 2 (ACE2), the key host cellular receptor of SARS-CoV-2, has been identified in ...

Ref: The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2 [Cardiovasc Res, 2020]


COVID-19 infection is associated with several cardiac complications with high rates of adverse outcomes.

... COVID-19 infection is associated with several cardiac complications with high rates of adverse outcomes. Cardiac imaging has different utility in different clinical scenarios, and the importance of minimizing healthcare worker exposure should be considered. Cardiac imaging should only be ordered if its benefits outweigh ...

Ref: The role of cardiac imaging in hospitalized COVID-19-positive patients. [Cleveland Clinic journal of medicine, 2020-05-14]


Studies evaluating patients with COVID-19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon.

... hypoxia, hypotension, enhanced inflammatory status, ACE2-receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating patients with COVID-19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID-19 are known to prolong the QT interval ...

Ref: Cardiac and arrhythmic complications in patients with COVID-19 [J Cardiovasc Electrophysiol, 2020]


A large percent of patients have underlying cardiovascular disease, and they are at a high risk of developing cardiac complications.

... in humans, accumulating data have demonstrated cardiac complications and poor outcome in patients with COVID-19. A large percent of patients have underlying cardiovascular disease, and they are at a high risk of developing cardiac complications. The basics of the virus, the clinical manifestations, and the possible mechanisms of cardiac complications ...

Ref: Coronavirus Disease-2019 (COVID-19) and Cardiovascular Complications [J. cardiothoracic vasc. anest, 2020]


Many patients with COVID-19 experience acute myocardial injury, as evident by an increase in cardiac troponin levels.

... Many patients with COVID-19 experience acute myocardial injury, as evident by an increase in cardiac troponin levels. A significant proportion of hospitalized patients, particularly those with severe illness developed heart failure (23%) (4). Moreover, troponin levels were significantly higher in patients admitted to the ICU and in ...

Ref: Management of Cardiovascular Disease During Coronavirus Disease (COVID-19) Pandemic [Trends Cardiovasc Med, 2020-05-28]


In severe cases, profound circulatory failure can result.

... both primary (arrhythmias, myocardial infarction, myocarditis) and secondary (myocardial injury/biomarker elevation, heart failure) cardiac involvement. In severe cases, profound circulatory failure can result. This review discusses the presentation and management of patients with severe cardiac complications of COVID-19 ...

Ref: Approach to Acute Cardiovascular Complications in COVID-19 Infection. [Circulation. Heart failure, 2020-06-05]


The observed cardiovascular complications associated with COVID-19 can be roughly characterized into 1: myocardial injury and heart failure 2: arrhythmias.

... were at a higher risk of death throughout the disease course compared to those without. Given these observations, much focus has been placed on better understanding cardiovascular sequelae of COVID19. The observed cardiovascular complications associated with COVID-19 can be roughly characterized into 1: myocardial injury and heart failure 2: arrhythmias. ...

Ref: Cardiovascular Risks in Patients with COVID-19: Potential Mechanisms and Areas of Uncertainty [Curr Cardiol Rep, 2020-04-29]


their cardiotoxicity which include arrhythmia, heart failure, myocardial disorder may be severe and irreversible 64 .

... cardiovascular system. Macrolides ( for example azithromycin) 61 Chloroquine/Hydroxychloroquine, which is an old drug for malaria, has been confirmed to be effective in patients with COVID-19 62, 63 . However, their cardiotoxicity which include arrhythmia, heart failure, myocardial disorder may be severe and irreversible 64 . ...

Ref: Coronavirus disease 2019 (COVID-19) and cardiovascular complications [J Cardiothorac Vasc Anesth, 2020-04-30]


Common symptoms: fever, dry cough, dyspnea, myalgias, fatigue, diarrhea, anosmia, dysgeusia.

Common symptoms: fever, dry cough, dyspnea, myalgias, fatigue, diarrhea, anosmia, dysgeusia.

Ref: Cardiovascular implications of the COVID-19 pandemic: a global perspective [Can J Cardiol, 2020-05-16]


medical complications affecting various organ systems are not uncommon, and may lead to critical illness and multi-organ failure.

... oxygen supplementation, as dictated by clinical need. For patients with moderate-to-severe COVID-19 that requires hospitalization, medical complications affecting various organ systems are not uncommon, and may lead to critical illness and multi-organ failure. Hence, the medical care of patients with COVID-19 is best optimized by the collaboration among ...

Ref: A Collaborative Multidisciplinary Approach to the Management of Coronavirus Disease-19 in the Hospital Setting [Mayo Clin Proc, 2020-05-30]


Some patients with COVID-19 may experience cardiac injury and arrhythmias [32] ,

... Some patients with COVID-19 may experience cardiac injury and arrhythmias [32] , and employment of echocardiography and cardiac enzymes would seem paramount in this setting [53] . Myocardial injury may occur due to a variety of mechanisms, from direct viral invasion of ...

Ref: The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease [Int J Cardiol, 2020-06-15]


Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19.

... Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8-12% of all patients. Direct myocardial injury due to viral involvement ...

Ref: Cardiovascular disease and COVID-19 [Diabetes Metab Syndr, 2020]


COVID-19 patients with pre-existing cardiovascular disease are counted in greater frequency in intensive care unit settings, and ultimately suffer greater rates of mortality.

... English literature was reviewed for papers dealing with the cardiac effects of COVID-19. RESULTS: Notably, COVID-19 patients with pre-existing cardiovascular disease are counted in greater frequency in intensive care unit settings, and ultimately suffer greater rates of mortality. Other studies have noted cardiac presentations for COVID-19, rather than respiratory, such as acute pericarditis ...

Ref: Cardiac involvement in COVID-19 patients: Risk factors, predictors, and complications: A review [J Card Surg, 2020]


Cardiovascular system often gets involved in later stages of the disease with acute cardiac injury, heart failure and arrhythmias being the common complications.

... of disease ranges from mild to severe with respiratory system being the most commonly affected. Cardiovascular system often gets involved in later stages of the disease with acute cardiac injury, heart failure and arrhythmias being the common complications. In addition, the presence of cardiovascular co-morbidities such as hypertension, coronary artery disease in these ...

Ref: Cardiovascular system and COVID-19: perspectives from a developing country. [Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2020-05-07]


Symptomatic patients usually present with fever, dry cough, and shortness of breath, which may appear 2 to 14 days after infection.

... Symptomatic patients usually present with fever, dry cough, and shortness of breath, which may appear 2 to 14 days after infection. 3 While it has been demonstrated that this virus has a predilection for the lungs and that respiratory complications are strongly associated with mortality, emerging reports show that cardiac involvement ...

Ref: Cardiac involvement in COVID‐19 patients: Risk factors, predictors, and complications: A review [J Card Surg, 2020-04-19]


Acute respiratory distress syndrome and respiratory failure, sepsis, acute cardiac injury, and heart failure were the most common critical complications

... deceased patients. CONCLUSION: Severe acute respiratory syndrome coronavirus 2 infection can cause both pulmonary and systemic inflammation, leading to multi-organ dysfunction in patients at high risk. Acute respiratory distress syndrome and respiratory failure, sepsis, acute cardiac injury, and heart failure were the most common critical complications during exacerbation of covid-19. ...

Ref: Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study [BMJ, 2020]


Cardiovascular risk factors and comorbidities are elevated in patients who have fatal outcomes after COVID-19 [9] .

... China. Therefore, there is no evidence that hypertension increases the likelihood to suffer from COVID-19. Cardiovascular risk factors and comorbidities are elevated in patients who have fatal outcomes after COVID-19 [9] . Therefore, all cardiovascular comorbidities in concert add to myocardial injury, which has been shown to ...

Ref: Coronavirus Disease 2019 (COVID-19) and its implications for cardiovascular care: expert document from the German Cardiac Society and the World Heart Federation [Clin Res Cardiol, 2020-05-27]


Patients diagnosed with COVID-19 should be monitored closely for the development of bradyarrhythmia and haemodynamic instability.

... both patients remain in sinus bradycardia. DISCUSSION: COVID-19-associated SND has not previously been described. The potential mechanisms for SND in patients with COVID-19 include myocardial inflammation or direct viral infiltration. Patients diagnosed with COVID-19 should be monitored closely for the development of bradyarrhythmia and haemodynamic instability. ...

Ref: Novel coronavirus 19 (COVID-19) associated sinus node dysfunction: a case series [Eur Heart J Case Rep, 2020-05-08]


Cardiovascular comorbidities are common in patients with severe COVID-19 and are associated with increased mortality.

... 38, 43 Conclusion COVID-19 pandemic has posed a severe health threat on an international scale. Cardiovascular comorbidities are common in patients with severe COVID-19 and are associated with increased mortality. Elevation of cardiac enzymes, suggesting acute cardiac injury, can occur in up to one-fourth of ...

Ref: Cardiovascular comorbidities and complications associated with coronavirus disease 2019 [Med J Armed Forces India, 2020-05-27]


Deaths from COVID-19 are due to cytokine storm syndrome and fulminant myocarditis.

... Deaths from COVID-19 are due to cytokine storm syndrome and fulminant myocarditis. Cytokine storm syndrome culminates as ARDS. Fulminant myocarditis is primarily caused by infection with viruses, with mortality rates as high as 50 to 70%. ...

Ref: Need of the Hour— COVID-19 for Cardiologists [Indian J Cardiovasc Dis Women WINCARS, 2020-04-16]


Strikingly, even 12 years after their SARS-CoV infection, half of all patients have residual cardiovascular abnormalities [53] .

... COVID-19 patients, SARS patients also develop cardiovascular complications, including impaired left ventricular function [52] . Strikingly, even 12 years after their SARS-CoV infection, half of all patients have residual cardiovascular abnormalities [53] . Moreover, Oudit et al. found that more than one-third of archived SARSinfected heart samples obtained ...

Ref: Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-Analysis [Research (Wash D C), 2020-04-19]


COVID patients with cardiac disease history or acquire new cardiac injury are at an increased risk for in-hospital morbidity and mortality.

... release syndrome. Potential treatments for reducing viral infection and excessive immune responses are also discussed. COVID patients with cardiac disease history or acquire new cardiac injury are at an increased risk for in-hospital morbidity and mortality. More studies are needed to address the mechanism of cardiotoxicity and the treatments that can ...

Ref: Cardiovascular Complications in Patients with COVID-19: Consequences of Viral Toxicities and Host Immune Response [Curr Cardiol Rep, 2020]


A cohort with 52 critically ill patients revealed cardiac injury in 12% of patients.

... during this pandemic. RECENT FINDINGS: Recent studies from Wuhan cohorts provide valuable information about COVID-19. A cohort with 52 critically ill patients revealed cardiac injury in 12% of patients. Worse outcomes appear to be more prevalent in patients with hypertension and diabetes mellitus (DM), ...

Ref: Outcomes in Patients with COVID-19 Infection Taking ACEI/ARB [Curr Cardiol Rep, 2020-04-14]


Some of the medications utilized to treat COVID-19 also have potential cardiac complications.

... number of cardiovascular complications, including myocardial injury and myocarditis, AMI, heart failure, dysrhythmias, and VTE. Some of the medications utilized to treat COVID-19 also have potential cardiac complications. It is important for the emergency clinicians to be aware of these complications when treating ...

Ref: Cardiovascular complications in COVID-19 [Am J Emerg Med, 2020-04-18]


One presented with congestive cardiac failure likely precipitated by COVID-19,

infiltrates. One presented with congestive cardiac failure likely precipitated by COVID-19, another was 81 asymptomatic but presented with hypertensive urgency; and the last case was admitted for ACS requiring 82

Ref: Surveillance for COVID-19 in cardiac inpatients: containing COVID-19 in a specialised cardiac centre [Can J Cardiol, 2020-05-29]


Other cardiovascular implications including arrythmia and heart failure also needs to be considered since they can be fatal.

... disease severity and mortality of COVID-19 patients. Hypertension, acute cardiac injury and coronary heart diseases in COVID-19 patients needs to be carefully monitored and managed in case of acute conditions. Other cardiovascular implications including arrythmia and heart failure also needs to be considered since they can be fatal. ...

Ref: Cardiovascular Diseases and COVID-19 Mortality and Intensive Care Unit Admission: A Systematic Review and Meta-analysis [Can J Cardiol, 2020-04-16]


A total of 82 patients (19.7%) had cardiac injury.

... [35] evaluated the impact of cardiac injury on mortality in 416 hospitalized patients with COVID-19. A total of 82 patients (19.7%) had cardiac injury. When comparing patients with to those without cardiac injury, the former were older, had a ...

Ref: Toward understanding the 2019 Coronavirus and its impact on the heart [J Thromb Thrombolysis, 2020-04-15]


One of the life‑threatening cardiac manifestations is coronavirus fulminant myocarditis, which may also occur without accompanying symptoms of pulmonary involvement.

... pro-B‑type natriuretic peptide concentration, and increased cardiac troponin level was found in 10% of patients. One of the life‑threatening cardiac manifestations is coronavirus fulminant myocarditis, which may also occur without accompanying symptoms of pulmonary involvement. Early recognition and treatment is crucial in these cases. So far, data on the incidence ...

Ref: What should a cardiologist know about coronavirus disease 2019? [Kardiologia polska, 2020-04-24]


The severity of COVID-19 is associated with acute cardiac injury, and acute cardiac injury is associated with death.

... 0.001). hsTnI and NT-proBNP levels increased during the course of hospitalization only in non-survivors. CONCLUSION: The severity of COVID-19 is associated with acute cardiac injury, and acute cardiac injury is associated with death. Cardiac injury biomarkers mainly increase in non-survivors. This highlights the need to effectively monitor heart ...

Ref: The impact of 2019 novel coronavirus on heart injury: A Systematic review and Meta-analysis [Prog. cardiovasc. dis, 2020]


The primary pulmonary injury and subsequent cardiovascular complications constitute the key pathophysiology of this deadly disease.

... influenza, the morbidity and transmission modality of COVID-19 appear more severe and uncontrollable 4 . The primary pulmonary injury and subsequent cardiovascular complications constitute the key pathophysiology of this deadly disease. This review updates and summarizes the pathophysiological features, possible underlying mechanisms, and clinical characteristics of ...

Ref: Pathophysiological Characteristics and Therapeutic Approaches for Pulmonary Injury and Cardiovascular Complications of Coronavirus Disease 2019 [Cardiovasc Pathol, 2020-04-17]


Hypertension, arrhythmia, cardiomyopathy and coronary heart disease are amongst major cardiovascular disease comorbidities seen in severe cases of COVID-19.

... likely to be infected with SARS-CoV-2 and they are more likely to develop severe symptoms. Hypertension, arrhythmia, cardiomyopathy and coronary heart disease are amongst major cardiovascular disease comorbidities seen in severe cases of COVID-19. There is growing literature exploring cardiac involvement in SARS-CoV-2. Myocardial injury is one of the ...

Ref: Myocardial injury and COVID-19: Possible mechanisms [Life Sci, 2020]


The mechanisms of cardiovascular injury from covid-19 have not been fully elucidated and are likely multifactorial.

... single-cell RNA sequencing, 14 which could mediate SARS-CoV-2 entry into cardiomyocytes and cause direct cardiotoxicity. The mechanisms of cardiovascular injury from covid-19 have not been fully elucidated and are likely multifactorial. SARS-CoV-2 viral particles have been identified by RT-PCR in cardiac tissue in some cases, 15 ...

Ref: Cardiovascular manifestations and treatment considerations in covid-19 [Heart, 2020-04-30]


mechanical complications of myocardial infarction leading to an increase in the number of cardiac arrests, unexplained deaths, heart failure, etc.).

... lack of attention, leading to severe consequences (an increase in the number of ambulatory myocardial infarctions, mechanical complications of myocardial infarction leading to an increase in the number of cardiac arrests, unexplained deaths, heart failure, etc.). Similar consequences can be feared for all acute situations, beyond the cardiovascular disease setting. ...

Ref: One train may hide another: Acute cardiovascular diseases could be neglected because of the COVID-19 pandemic [Arch Cardiovasc Dis, 2020]


The elevation in cardiac markers was probably due to secondary and systemic consequences and can be considered as the warning sign for recent adverse clinical outcomes of the patients.

... echocardiography and electrocardiogram. CONCLUSIONS: The clinical evidence in our study suggested that myocardial injury is more likely related to systemic consequences rather than direct damage by the 2019 novel coronavirus. The elevation in cardiac markers was probably due to secondary and systemic consequences and can be considered as the warning sign for recent adverse clinical outcomes of the patients. ...

Ref: Suspected myocardial injury in patients with COVID-19: Evidence from front-line clinical observation in Wuhan, China [Int J Cardiol, 2020]


A small subset of patients with cardiovascular complications from COVID-19 infection may progress to refractory CS.

... specific to the COVID-19 pandemic were formulated with guidance from published data and expert consensus. A small subset of patients with cardiovascular complications from COVID-19 infection may progress to refractory CS. Accepting that resource scarcity may be the overwhelming concern for healthcare systems during this pandemic, ...

Ref: Cardiovascular Collapse in COVID-19 Infection: The Role of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) [Int J Cardiol, 2020]


Chronic cardiovascular disease also may become unstable as a consequence of imbalance between infection-induce increased metabolic demand and reduced cardiac reserve.

... mechanism to the heart. in oxygen supply, destabilization of coronary plaque, and micro thrombogenesis. [3] Chronic cardiovascular disease also may become unstable as a consequence of imbalance between infection-induce increased metabolic demand and reduced cardiac reserve. Acute coronary events in patients with COVID-19 may result from the significant increase in myocardial ...

Ref: Coronavirus Disease 2019 and Cardiovascular System: A Narrative Review [Int J Cardiol Heart Vasc, 2020-06-03]


When COVID-19 is complicated by acute myocardial injury, a significant increase in mortality occurs.

... data. Myocardial injury is associated with inflammation, impairment of cardiac function, and malignant ventricular tachyarrhythmias. When COVID-19 is complicated by acute myocardial injury, a significant increase in mortality occurs. Furthermore, this novel disease may be complicated by myocarditis and heart failure. We urge physician ...

Ref: A Review of Cardiac Complications in Coronavirus Disease 2019 [Cureus, 2020-05-08]


COVID-19 patients with underlying cardiovascular comorbidities, including CVD and hypertension, may face a greater risk of fatal outcomes.

... associated with a higher unadjusted odds of 21.15 (95% CI 10.19 to 43.94; I(2)=71%). CONCLUSION: COVID-19 patients with underlying cardiovascular comorbidities, including CVD and hypertension, may face a greater risk of fatal outcomes. Acute cardiac injury may act as a marker of mortality risk. Given the unadjusted results ...

Ref: Impact of cardiovascular disease and cardiac injury on in-hospital mortality in patients with COVID-19: a systematic review and meta-analysis [Heart, 2020-05-27]


An analysis of the cause of death suggested that the patient died of heart failure and systemic multiple organ dysfunction.

... Shanghai was in an individual who was 88 years old with a severe history of hypertension and cardiac insufficiency. An analysis of the cause of death suggested that the patient died of heart failure and systemic multiple organ dysfunction. Therefore, SARS-CoV-2 infection was just an inducement for exacerbations [124] . ...

Ref: cord_uid xhf8yg6o Advances in the relationship between coronavir... xhf8yg6o Advances in the Relationship Between Coronavir... Name: title, dtype: object [Heart, cord_uid xhf8yg6o 2020-05-13 xhf8yg6o 2020-05-13 Name: publish_time, dtype: object]


a synthetic summary of current knowledge is needed to help clinicians who care for patients with cardiovascular disease, especially heart failure (HF) patients.

... around the world. Due to the limited information on heart dysfunction in patients with COVID-19, a synthetic summary of current knowledge is needed to help clinicians who care for patients with cardiovascular disease, especially heart failure (HF) patients. We present the expert opinion of the Polish Cardiac Society - Working Group of Heart ...

Ref: Expert opinion of the Working Group on Heart Failure of the Polish Cardiac Society: the patient with heart failure facing the COVID-19 pandemic [Kardiol. pol, 2020]


Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, some patients have severe cardio vascular damage 3 .

... The rapid increase in confirmed cases makes the prevention and control of COVID-19 extremely serious. Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, some patients have severe cardio vascular damage 3 . In addition, some patients with underlying cardiovascular diseases (CVDs) might have an increased risk of ...

Ref: COVID-19 and the cardiovascular system [Nat Rev Cardiol, 2020-03-05]


myocardial injury, myocarditis, acute coronary syndromes, pulmonary embolism, stroke, arrhythmias, heart failure, and cardiogenic shock.

... the clinical presentation, COVID-19 is now known to also have potentially serious cardiovascular consequences, including myocardial injury, myocarditis, acute coronary syndromes, pulmonary embolism, stroke, arrhythmias, heart failure, and cardiogenic shock. The cardiac manifestations of COVID-19 might be related to the adrenergic drive, systemic inflammatory milieu ...

Ref: Cardiovascular implications of the COVID-19 pandemic: a global perspective [Can. j. cardiol, 2020]


should not be overlooked due to the presence of COVID-19 infection.

... responsible for COVID-19, can determine cardiac events, which require a quick diagnosis and management, and should not be overlooked due to the presence of COVID-19 infection. In some cases, cardiovascular symptoms can also be the first and only manifestation of SARS-CoV-2 ...

Ref: The role of echocardiography in SARS-CoV-2 pandemic: a compromise among appropriateness, safety and clinical impact [Monaldi arch. chest dis, 2020]


Patients with COVID-19 who suffer a cardiovascular complication are high-risk patients and should be screened for enrollment in clinical trials.

... COVID-19 infection remains supportive therapy, but clinical trials have proliferated in response to this pandemic. Patients with COVID-19 who suffer a cardiovascular complication are high-risk patients and should be screened for enrollment in clinical trials. In our "Drug Considerations" heading, we provide some guidance around possible cardiovascular interactions with these ...

Ref: A care pathway for the cardiovascular complications of COVID-19: Insights from an institutional response [Am Heart J, 2020-05-03]


Myocardial injury is not an uncommon complication among patients with severe COVID-19, especially among those who die.

... Myocardial injury is not an uncommon complication among patients with severe COVID-19, especially among those who die. cTnI and CK-MB levels predict risk for in-hospital death, and myocardial injury is associated with senior age, inflammatory response, and cardiovascular-related comorbidities. ...

Ref: Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 [Eur Heart J, 2020-05-11]


There was higher mortality when COVID-19 was associated with acute myocarditis, acute myocardial infarction, and rapid-onset heart failure.

... with known coronary artery disease and heart failure patients were at higher risk than others. There was higher mortality when COVID-19 was associated with acute myocarditis, acute myocardial infarction, and rapid-onset heart failure. 1 This observation clearly suggests that cardiovascular involvement and especially cardiac injury is possibly associated ...

Ref: Potential Mechanisms of Cardiac Injury and Common Pathways of Inflammation in Patients With COVID-19 [Crit Pathw Cardiol, 2020-06-09]


patients with pre-existing CAD or underlying heart failure seem to be susceptible to myocardial injury.

... morality. Myocardial injury and myocardiopathy are present in a considerable number of critical cases and patients with pre-existing CAD or underlying heart failure seem to be susceptible to myocardial injury. Despite the theoretical concerns and uncertainty regarding the effect of RAAS inhibitors on ACE2 and ...

Ref: Impact of COVID-19 on the Cardiovascular System: A Review [J Clin Med, 2020-05-09]


SARS-CoV-2 infection related acute cardiac injury cannot be ignored, and its underlying mechanisms remain speculated.

... its host receptor, ACE2-related signaling pathways may play a key role in mediating myocardial injury. SARS-CoV-2 infection related acute cardiac injury cannot be ignored, and its underlying mechanisms remain speculated. We would suggest that health professionals investigate cardiac function as part of the routine care. ...

Ref: 2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored [Curr Atheroscler Rep, 2020]


Complications including ACLF, acute cardiac injury and shock happened more frequently in patients with liver injury (all P<0.05).

... failure. The proportion of severe COVID-19 was higher in patients with liver injury (P= 0.042). Complications including ACLF, acute cardiac injury and shock happened more frequently in patients with liver injury (all P<0.05). The mortality was higher in individuals with liver injury (28.57% vs 3.30%, P=0.004). Conclusion Liver ...

Ref: Characteristics of liver function in patients with SARS-CoV-2 and chronic HBV co-infection [Clin Gastroenterol Hepatol, 2020-06-15]


elderly patients with cardiovascular illness have higher rates of acute coronary syndromes, cardiac arrhythmias, and heart failure-related events (7) .

We have learned that during an influenza outbreak, elderly patients with cardiovascular illness have higher rates of acute coronary syndromes, cardiac arrhythmias, and heart failure-related events (7) .

Ref: COVID-19 Illness and Heart Failure: A Missing Link? [JACC Heart Fail, 2020-04-10]


COVID-19 results in mild symptoms in the majority of infected patients, but can cause severe lung injury, cardiac injury, and death.

... is most likely of zoonotic origin, but has been shown to have effective human-to-human transmission. COVID-19 results in mild symptoms in the majority of infected patients, but can cause severe lung injury, cardiac injury, and death. Given the novel nature of COVID-19, no established treatment beyond supportive care exists currently, but ...

Ref: The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease [Int J Cardiol, 2020]


The impact of pre-existing CVD and new onset cardiac complications on clinical outcomes in these patients is also discussed.

... review is aimed at providing overview of various CV manifestations in patients presenting with COVID-19. The impact of pre-existing CVD and new onset cardiac complications on clinical outcomes in these patients is also discussed. Since our understanding on this subject is only evolving at this stage, the information contained ...

Ref: Cardiovascular disease and COVID-19 [Diabetes Metab Syndr, 2020-03-25]


Many patients develop myocardial injury which can lead to significant cardiovascular complications including HF.

... global pandemic has engulfed humanity with a huge impact on health systems across the world. Many patients develop myocardial injury which can lead to significant cardiovascular complications including HF. This will require aggressive management strategies which are evolving. Guideline directed drug therapy including ACEI/ARB/ARNI ...

Ref: Cardiological society of India position statement on COVID-19 and heart failure [Indian Heart J, 2020-05-13]


COVID‐19 patients with pre‐existing cardiovascular disease are counted in greater frequency in intensive care unit settings, and ultimately suffer greater rates of mortality.

... English literature was reviewed for papers dealing with the cardiac effects of COVID‐19. RESULTS: Notably, COVID‐19 patients with pre‐existing cardiovascular disease are counted in greater frequency in intensive care unit settings, and ultimately suffer greater rates of mortality. Other studies have noted cardiac presentations for COVID‐19, rather than respiratory, such as acute pericarditis ...

Ref: Cardiac involvement in COVID‐19 patients: Risk factors, predictors, and complications: A review [J Card Surg, 2020-04-19]


Acute respiratory distress syndrome, heart failure, renal failure, liver damage, shock and multi-organ failure have precipitated death.

... of SARS-CoV-2 on body-wide organs via ACE2, has been associated with complications of the disease. Acute respiratory distress syndrome, heart failure, renal failure, liver damage, shock and multi-organ failure have precipitated death. Acknowledging the comorbidities and potential organ injuries throughout the course of COVID-19 is therefore crucial ...

Ref: COVID-19 and Multi-Organ Response [Curr Probl Cardiol, 2020-04-28]


COVID-19 has the potential to cause significant cardiovascular compromise warranting consideration for advanced therapies in a small subset of affected patients.

... COVID-19 has the potential to cause significant cardiovascular compromise warranting consideration for advanced therapies in a small subset of affected patients. Frontline providers of all specialties must stay up-to-date with the ever-evolving literature and be familiar with therapeutic options for COVID-19 infections. VV and VA-ECMO remain a resource-intensive form of respiratory ...

Ref: Cardiovascular Collapse in COVID-19 Infection: The Role of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) [CJC Open, 2020-04-08]


Acute myocardial injury is the most commonly described CV complication in COVID-19 (Table 1 ).

... Acute myocardial injury is the most commonly described CV complication in COVID-19 (Table 1 ). Different reports have used different definitions for acute myocardial injury, including rise in cardiac enzymes (different biomarkers and cut-offs) and/or electrocardiographic abnormalities. However, an elevation of highsensitivity cardiac troponin I ...

Ref: Cardiovascular disease and COVID-19 [Diabetes Metab Syndr, 2020-03-25]


Some patients are hospitalized for moderate to severe sternal or leg infection under intravenous antibiotics.

... Chronic wound management. Some patients are hospitalized for moderate to severe sternal or leg infection under intravenous antibiotics. These patients, according to the severity of wound dehiscence and sternal stability, should be switched to oral antibiotics and managed with long-acting wound therapy (such as vacuum-assisted ...

Ref: The COVID-19 outbreak and its impact on hospitals in Italy: the model of cardiac surgery [Eur J Cardiothorac Surg, 2020-04-17]


the exact mechanism of cardiac injury among patients with COVID-19 still remains uncertain.

... Due to the lack of prospective, randomized, controlled clinical studies on inflammation and cardiovascular involvement, the exact mechanism of cardiac injury among patients with COVID-19 still remains uncertain. It was demonstrated that there is a high and significantly positive linear correlation between troponin ...

Ref: Potential mechanisms of cardiac injury and common pathways of inflammation in patients with COVID-19 [Eur J Cardiothorac Surg, 2020]


likely encompass acute coronary syndromes, myocarditis, cardiomyopathies, cardiogenic shock, lethal arrhythmias, and sudden cardiac death.

... Several recent Chinese studies have since demonstrated the sequelae of CV events. [5] [6] [7] As the pandemic evolves, the emerging literature on CV outcomes are not well characterized, but likely encompass acute coronary syndromes, myocarditis, cardiomyopathies, cardiogenic shock, lethal arrhythmias, and sudden cardiac death. ...

Ref: Atrial Arrhythmias in a Patient Presenting With Coronavirus Disease-2019 (COVID-19) Infection [J Investig Med High Impact Case Rep, 2020-05-05]


Of the patients hospitalised for COVID-19 thus far, the prevalence of cardiovascular comorbidities has been staggering.

... is not ignored and to recognise those presenting with early signs of acute myocardial injury. Of the patients hospitalised for COVID-19 thus far, the prevalence of cardiovascular comorbidities has been staggering. Based on early reports, patients with cardiovascular disease (CVD) may represent 25% of those in ...

Ref: Prognostic Value of Cardiovascular Biomarkers in COVID-19: A Review [Viruses, 2020-05-11]


diabetes mellitus, and known coronary artery disease were associated with adverse outcomes in COVID- 19 .

... a hyper-inflammatory response to the virus causing systemic effects, including those on the cardiovascular system. diabetes mellitus, and known coronary artery disease were associated with adverse outcomes in COVID- 19 . In a survey by the China CDC, among patients diagnosed with COVID-19, 13% had hypertension, ...

Ref: A current review of COVID-19 for the cardiovascular specialist [Am Heart J, 2020-05-03]


Cardiac complications include acute myocardial injury, arrhythmias, cardiogenic shock and even sudden death.

... range from asymptomatic to mild respiratory symptoms and even potentially life-threatening cardiovascular and pulmonary complications. Cardiac complications include acute myocardial injury, arrhythmias, cardiogenic shock and even sudden death. Furthermore, drug interactions with COVID-19 therapies may place the patient at risk for arrhythmias, cardiomyopathy ...

Ref: SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart [Heart Lung Circ, 2020-06-05]


common complications included arrhythmias in 16.7% of cases and acute cardiac injury in 7.2% [2] .

... arrhythmic cardiac death during hospitalization. Nevertheless, a previous report in 138 COVID-19 patients showed that common complications included arrhythmias in 16.7% of cases and acute cardiac injury in 7.2% [2] . This was confirmed in another recent report in 187 patients with COVID-19 demonstrating malignant arrhythmias ...

Ref: SARS-CoV-2 inflames the heart. The importance of awareness of myocardial injury in COVID-19 patients [Int J Cardiol, 2020-04-06]


it is associated with higher risk of in-hospital mortality.

Conclusions and Relevance: Cardiac injury is a common condition among hospitalized patients with COVID-19 in Wuhan, China, and it is associated with higher risk of in-hospital mortality.

Ref: Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China [JAMA cardiol. (Online), 2020]


was found to have purulent fulminant myopericarditis and cardiac tamponade, with subsequent circulatory shock.

We report a patient with Covid-19 who presented with findings of acute coronary syndrome and was found to have purulent fulminant myopericarditis and cardiac tamponade, with subsequent circulatory shock.

Ref: Coronavirus Disease 2019 (Covid-19) presenting as purulent fulminant myopericarditis and cardiac tamponade: a case report and literature review. [Heart Lung, 2020-06-09]


COVID-19 is associated with higher incidence of cardiovascular complications compared to previous coronavirus outbreaks (SARS-CoV, MERS-CoV).

... reviewed existing literature surrounding the role of VA-ECMO in the treatment of coronavirus-related cardiovascular collapse. COVID-19 is associated with higher incidence of cardiovascular complications compared to previous coronavirus outbreaks (SARS-CoV, MERS-CoV). We found only one case report from China where COVID-19-associated fulminant myocarditis and cardiogenic shock ...

Ref: Cardiovascular Collapse in COVID-19 Infection: The Role of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) [Heart Lung, 2020]


Patients with a more severe form of COVID-19 are also more likely to develop cardiac complications such as myocardial injury and arrhythmia.

... suggest cardiovascular risk factors are associated with increased disease severity and mortality in COVID-19 patients. Patients with a more severe form of COVID-19 are also more likely to develop cardiac complications such as myocardial injury and arrhythmia. The true incidence of and mechanism underlying these events remain elusive. Cardiovascular diseases appear intricately ...

Ref: Cardiovascular Risks in Patients with COVID-19: Potential Mechanisms and Areas of Uncertainty [Curr Cardiol Rep, 2020]


COVID-19 patients with heart, liver and kidneycomorbidity, compared to patients without related comorbidities, were more likely to have cardiac injuries

... were enrolled in this retrospective cohort study.Results: A total of 212 COVID-19 patients were included. COVID-19 patients with heart, liver and kidneycomorbidity, compared to patients without related comorbidities, were more likely to have cardiac injuries [9.1%(3/33) vs 2.2%(4/179), P = 0.043], liver injuries [13.0%(3/23) vs 3.2%(6/189), P = 0.027], kidney ...

Ref: The role of essential organ-based comorbidities in the prognosis of COVID-19 infection patients [Expert Rev Respir Med, 2020]


Myocarditis-related cardiac dysfunction and potentially life-threatening arrhythmias are the main aftermaths.

... also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and potentially life-threatening arrhythmias are the main aftermaths. A few studies showed that myocardial injury in adult patients is often linked with a ...

Ref: Children's heart and COVID-19: Up-to-date evidence in the form of a systematic review [Eur. j. pediatr, 2020]


we found that cardiovascular complications are common in COVID-19 patients and include tachycardia, elevated myocardial enzyme levels, cardiac dysfunction, and even AMI.

... In summary, we found that cardiovascular complications are common in COVID-19 patients and include tachycardia, elevated myocardial enzyme levels, cardiac dysfunction, and even AMI. More importantly, CRP level elevation, NCP severity, and underlying cardiovascular diseases are the major risk factors for AMI in these patients. ...

Ref: Acute Myocardial Injury of Patients with Coronavirus Disease 2019 [Eur. j. pediatr, 2020-03-08]


Furthermore, this novel disease may be complicated by myocarditis and heart failure.

... tachyarrhythmias. When COVID-19 is complicated by acute myocardial injury, a significant increase in mortality occurs. Furthermore, this novel disease may be complicated by myocarditis and heart failure. We urge physician awareness of the elevated morbidity and mortality of myocardial involvement in COVID-19. ...

Ref: A Review of Cardiac Complications in Coronavirus Disease 2019 [Cureus, 2020-05-08]


Disruption of ACE-2 leads to an age-dependent cardiomyopathy, cardiac dysfunction, and heart failure [42, 43] .

... previously, human SARS-CoV infection of the myocardium is known to be dependent on ACE-2 receptors. Disruption of ACE-2 leads to an age-dependent cardiomyopathy, cardiac dysfunction, and heart failure [42, 43] . Oudit et. al, hypothesized that the interaction between SARS-CoV and ACE-2 in the heart could ...

Ref: Myocardial injury and COVID-19: Possible mechanisms [Life Sci, 2020-04-28]


As most of the COVID-19 patients have cardiovascular comorbidities like hypertension, diabetes, coronary artery disease and heart failure,

... on whether treatment with cardiovascular drugs, which upregulate the viral receptor ACE2 should be modified. As most of the COVID-19 patients have cardiovascular comorbidities like hypertension, diabetes, coronary artery disease and heart failure, which imposes a high risk on these patients, cardiovascular therapy should not be modified or ...

Ref: Coronavirus Disease 2019 (COVID-19) and its implications for cardiovascular care: expert document from the German Cardiac Society and the World Heart Federation [Clin. res. cardiol, 2020]


The high mortality in COVID-19 is very likely due to cytokine storm and fulminant myocarditis.

... Cardiac injury is associated with mortality, need for ICU care, and severity of disease in patients with COVID-19. The high mortality in COVID-19 is very likely due to cytokine storm and fulminant myocarditis. ...

Ref: Cardiac injury is associated with mortality and critically ill pneumonia in COVID-19: A meta-analysis [Am J Emerg Med, 2020-04-19]


a significant increase in mortality occurs. Furthermore, this novel disease may be complicated by myocarditis and heart failure.

... of cardiac function, and malignant ventricular tachyarrhythmias. When COVID-19 is complicated by acute myocardial injury, a significant increase in mortality occurs. Furthermore, this novel disease may be complicated by myocarditis and heart failure. We urge physician awareness of the elevated morbidity and mortality of myocardial involvement in COVID-19. ...

Ref: A Review of Cardiac Complications in Coronavirus Disease 2019 [Cureus, 2020-05-08]


Cardiac disease and diabetes increase the risk of death by twice as much as other risk factors [20] .

... cardiac disease and diabetes being the most important components to predict adverse outcomes [20] . Cardiac disease and diabetes increase the risk of death by twice as much as other risk factors [20] . Thus, it is necessary for us to evaluate the prevalence of cardiac and metabolic diseases ...

Ref: Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China [Clin Res Cardiol, 2020-03-11]


Cardiac complications, including new or worsening heart failure, new or worsening arrhythmia, or myocardial infarction are common in patients with pneumonia.

... Cardiac complications, including new or worsening heart failure, new or worsening arrhythmia, or myocardial infarction are common in patients with pneumonia. Cardiac arrest occurs in about 3% of inpatients with pneumonia. 21 Risk factors of cardiac events after pneumonia include older age, pre-existing cardiovascular diseases, and greater severity of pneumonia at ...

Ref: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study [Lancet, 2020-03-11]


Studies evaluating patients with COVID‐19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon.

... hypoxia, hypotension, enhanced inflammatory status, ACE2‐receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating patients with COVID‐19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID‐19 are known to prolong the QT interval ...

Ref: Cardiac and arrhythmic complications in patients with COVID‐19 [J Cardiovasc Electrophysiol, 2020-04-13]


heart failure are more susceptible to coronavirus disease 2019 (COVID-19) and have a more severe clinical course once infected.

... Patients with cardiovascular disease and, namely, heart failure are more susceptible to coronavirus disease 2019 (COVID-19) and have a more severe clinical course once infected. Heart failure and myocardial damage, shown by increased troponin plasma levels, occur in at least 10% of patients hospitalized for COVID-19 with higher percentages, ...

Ref: COVID 19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease [Eur. j. heart fail, 2020]


Monitoring may include serial cardiac troponin and natriuretic peptides, along with fibrinogen, D-dimer, and inflammatory biomarkers.

... adverse outcomes in patients with COVID-19. Practitioners should be vigilant for cardiovascular complications of COVID-19. Monitoring may include serial cardiac troponin and natriuretic peptides, along with fibrinogen, D-dimer, and inflammatory biomarkers. Management decisions should rely on the clinical assessment for the probability of ongoing myocardial ischemia, ...

Ref: A current review of COVID-19 for the cardiovascular specialist [Am Heart J, 2020]


HFNCO is an effective treatment modality for COVID-19-associated acute respiratory failure.

... HFNCO is an effective treatment modality for COVID-19-associated acute respiratory failure. Particularly in patients with mild to moderate ARDS and in negative pressure rooms, it could be a viable initial alternative to mechanical ventilation. ...

Ref: Mechanisms of Myocardial Injury in Coronavirus Disease 2019 [Card Fail Rev, 2020-05-25]


cardiovascular complications of coronavirus disease 2019 are highly prevalent and include acute cardiac injury, myocarditis, and a hypercoagulable state,

... by infecting or passing from the respiratory epithelium to the endothelium for viral dissemination. Indeed, cardiovascular complications of coronavirus disease 2019 are highly prevalent and include acute cardiac injury, myocarditis, and a hypercoagulable state, all of which may be influenced by altered endothelial function. Notably, the disease course is ...

Ref: Overcoming Barriers: The Endothelium As a Linchpin of Coronavirus Disease 2019 Pathogenesis? [Arteriosclerosis, thrombosis, and vascular biology, 2020-06-08]


can cause severe lung injury, cardiac injury, and death.

... effective human-to-human transmission. COVID-19 results in mild symptoms in the majority of infected patients, but can cause severe lung injury, cardiac injury, and death. Given the novel nature of COVID-19, no established treatment beyond supportive care exists currently, but ...

Ref: The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease [Int J Cardiol, 2020]


As soon as such patients were confirmed or suspected as COVID-19, a sudden acute myocardial infarction, or heart failure will occur immediately.

... As soon as such patients were confirmed or suspected as COVID-19, a sudden acute myocardial infarction, or heart failure will occur immediately. It is so important to early identify those patients with acquired quarantine measures. ...

Ref: A close-up on COVID-19 and cardiovascular diseases [Nutr Metab Cardiovasc Dis, 2020-04-08]


According to the definition, 14 (12.5%) COVID-19 patients possibly had myocarditis.

... According to the definition, 14 (12.5%) COVID-19 patients possibly had myocarditis. The characteristics of these patients were summarized in Table 3 and Supplementary Table 1 . All the patients possibly with myocarditis had elevation in creatine kinase MB and NT-pro BNP. ...

Ref: Suspected myocardial injury in patients with COVID-19: Evidence from front-line clinical observation in Wuhan, China() [Int J Cardiol, 2020-04-08]


concurrent cardiac injury cannot be ignored since it may be an independent predictor for adverse outcomes.

... respiratory syndrome coronavirus-2 (SARS-CoV-2), has reached a pandemic status. Although SARSCoV-2 causes primarily respiratory problems, concurrent cardiac injury cannot be ignored since it may be an independent predictor for adverse outcomes. To resolve these issues, we aim to summarize the prevalence and its underlying mechanisms of ...

Ref: 2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored [Curr Atheroscler Rep, 2020-05-07]


Other patients develop severe pneumonia, which can eventually cause acute respiratory distress syndrome (ARDS) and death.

... is extremely variable. It may be asymptomatic or cause mild symptoms such as fever, dry cough and fatigue. Other patients develop severe pneumonia, which can eventually cause acute respiratory distress syndrome (ARDS) and death. First reports already This article is protected by copyright. All rights reserved. ...

Ref: COVID 19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease [Eur J Heart Fail, 2020-05-15]


COVID-19 can, in turn, aggravate the damage to the heart.

... cardiovascular metabolic diseases may face a greater risk of developing into the severe condition and the comorbidities can also greatly affect the prognosis of the COVID-19. On the other hand, COVID-19 can, in turn, aggravate the damage to the heart. ...

Ref: Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China [Clin Res Cardiol, 2020]


Some included coronary heart disease and heart failure, whereas others also included cerebrovascular disease.

... other comorbidities such as diabetes and kidney impairment. One should notice that different studies used various definitions of CVD. Some included coronary heart disease and heart failure, whereas others also included cerebrovascular disease. Therefore, one should be cautious in the interpretation of these results. ...

Ref: cord_uid bwkad2s0 COVID-19, hypertension and cardiovascular dise... bwkad2s0 COVID-19, hypertension and cardiovascular dise... Name: title, dtype: object [Clin Res Cardiol, cord_uid bwkad2s0 2020-05-13 bwkad2s0 2020-05-13 Name: publish_time, dtype: object]