¿Qué tipo de complicaciones relacionadas con la COVID-19 se asocian a la diabetes?

(What kinds of complications related to covid-19 are associated with diabetes)

Primeras 5 respuestas:

Risk factors for lethality in COVID-19 include early-onset diabetes, obesity, COPD, advanced age, hypertension, immunosuppression, and CKD;

Patients with adverse reactions often have comorbidities, especially hypertension.

More than half were worried about being overly affected due to diabetes if infected with COVID-19,

interference of comorbidities such as obesity and hypertension, and type of glucose-lowering therapy, among others.

infections, hyperosmolar coma, ketoacidosis and even acute cardiac events.

Risk factors for lethality in COVID-19 include early-onset diabetes, obesity, COPD, advanced age, hypertension, immunosuppression, and CKD;

... 177,133 subjects at May 18th, 2020, we observed 51,633 subjects with SARS-CoV-2 and 5,332 deaths. Risk factors for lethality in COVID-19 include early-onset diabetes, obesity, COPD, advanced age, hypertension, immunosuppression, and CKD; we observed that obesity mediates 49.5% of the effect of diabetes on COVID-19 lethality. Early-onset ...

Ref: Predicting mortality due to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico. [The Journal of clinical endocrinology and metabolism, 2020-05-31]

Patients with adverse reactions often have comorbidities, especially hypertension.

... also treated with ARB and 2 had received an NSAID. These data show that patients with diabetes are also subject to serious adverse reactions to the drugs used in COVID-19. Patients with adverse reactions often have comorbidities, especially hypertension. ...

Ref: cord_uid o99mtt0v Diabetes and COVID-19. o99mtt0v Diabetes and COVID-19 Name: title, dtype: object [The Journal of clinical endocrinology and metabolism, cord_uid o99mtt0v 2020-05-15 o99mtt0v 2020-05-15 Name: publish_time, dtype: object]

More than half were worried about being overly affected due to diabetes if infected with COVID-19,

... statistics and logistic regressions. RESULTS: People with diabetes have COVID-19-specific worries related to their diabetes. More than half were worried about being overly affected due to diabetes if infected with COVID-19, about one-third about being characterized as a risk group due to diabetes and not being ...

Ref: Diabetes and COVID-19: psychosocial consequences of the COVID-19 pandemic in people with diabetes in Denmark-what characterizes people with high levels of COVID-19-related worries? [Diabet. med, 2020]

interference of comorbidities such as obesity and hypertension, and type of glucose-lowering therapy, among others.

... of type of diabetes, duration of disease, quality of glucose control, presence of diabetic complications, interference of comorbidities such as obesity and hypertension, and type of glucose-lowering therapy, among others. Which of these different factors could be playing a significant role in the final prognosis ...

Ref: Prognostic factors in patients with diabetes hospitalized for COVID-19: Findings from the CORONADO study and other recent reports [Diabetes Metab, 2020-05-21]

infections, hyperosmolar coma, ketoacidosis and even acute cardiac events.

... All these factors could cause glucose dysregulation and could predispose the patients to complications like infections, hyperosmolar coma, ketoacidosis and even acute cardiac events. Care should be taken not to vary the calorie intake markedly. Healthy balanced diet with ...

Ref: Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations [Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2020-08-31]

Patients with diabetes have an increased risk of severe complications including Adult Respiratory Distress Syndrome and multi-organ failure.

... of all three known human pathogenic coronavirus infections, including severe acute respiratory syndrome coronavirus 2. Patients with diabetes have an increased risk of severe complications including Adult Respiratory Distress Syndrome and multi-organ failure. Depending on the global region, 20-50% of patients in the coronavirus disease 2019 (COVID-19) pandemic ...

Ref: Practical recommendations for the management of diabetes in patients with COVID-19 [Lancet Diabetes Endocrinol, 2020]

the worsening of hyperglycaemia an increase in diabetes-related complications.

... likely to be issues related to the impact of this lockdown on patients with diabetes; the worsening of hyperglycaemia an increase in diabetes-related complications. This could be due to the limitation of free space to exercise, limited resources to ...

Ref: Estimation of effects of nationwide lockdown for containing coronavirus infection on worsening of glycosylated haemoglobin and increase in diabetes-related complications: A simulation model using multivariate regression analysis [Diabetes Metab Syndr, 2020-04-10]

Older age, multi-morbidity, hyperglycaemia, cardiac injury and severe inflammatory response are predictors of poor outcome.

... diabetes and related comorbidities are at increased risk of its complications and of COVID-19-related death. Older age, multi-morbidity, hyperglycaemia, cardiac injury and severe inflammatory response are predictors of poor outcome. The complex interplay between COVID-19, diabetes and the effects of related therapies is being explored. ...

Ref: Prevention and management of COVID-19 among patients with diabetes: an appraisal of the literature [Diabetologia, 2020]

their association with glucose-lowering or blood pressure-lowering medications.

... has been confirmed or clinically diagnosed (with typical features on lung imaging and symptoms), and their association with glucose-lowering or blood pressure-lowering medications. RESEARCH DESIGN AND METHODS: In this retrospective study involving 904 patients with COVID-19 (136 with ...

Ref: Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication [Diabetes care, 2020]

early-onset diabetes obesity, chronic obstructive pulmonary disease, advanced age, immunosuppression, and chronic kidney disease;

... with diabetes and age <40 years (early-onset). Risk factors for increased lethality in COVID-19 includes early-onset diabetes obesity, chronic obstructive pulmonary disease, advanced age, immunosuppression, and chronic kidney disease; we also found that obesity mediates 47.8% of the effect of diabetes on COVID-19 lethality. ...

Ref: Predicting mortality attributable to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico [Diabetes care, 2020-04-24]

Older age and comorbid hypertension independently contributed to in-hospital death of patients with diabetes.

... CI 1.14-8.44) were independent risk factors for in-hospital death of patients with diabetes. CONCLUSIONS: COVID-19 patients with diabetes had worse outcomes compared with the sex- and age-matched patients without diabetes. Older age and comorbid hypertension independently contributed to in-hospital death of patients with diabetes. ...

Ref: Clinical Characteristics and Risk Factors for Mortality of COVID-19 Patients With Diabetes in Wuhan, China: A Two-Center, Retrospective Study [Diabetes care, 2020]

vasculopathy, coagulopathy as well as psychological stress.

... and a resultant hyperglycemic state. These individuals may be prone to worsened COVID-19 complications including vasculopathy, coagulopathy as well as psychological stress. Apart from general preventive measures, remaining hydrated, monitoring blood glucose regularly and monitoring ketone bodies ...

Ref: COVID-19 and diabetes: The why, the what and the how [J Diabetes Complications, 2020-05-22]

underlying comorbidities like cardiovascular conditions, diabetes, and hypertension, and cancer [2] .

... suggested that patients with COVID-19 infection have a high burden of complications [1] , and underlying comorbidities like cardiovascular conditions, diabetes, and hypertension, and cancer [2] . A recent meta-analysis of studies published in China reported a pooled diabetes prevalence of 10.3% ...

Ref: COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis [Diabetes Metab Syndr, 2020-05-12]

Patients with diabetes had a significantly more severe variety of COVID-19 and increased mortality, compared to the groups without diabetes.

... to the topic. RESULTS: There is a high prevalence of diabetes in patients with COVID-19. Patients with diabetes had a significantly more severe variety of COVID-19 and increased mortality, compared to the groups without diabetes. Moreover, poor glycemic control is associated with a significantly higher severe variety of COVID-19 and ...

Ref: Assessment of risk, severity, mortality, glycemic control and antidiabetic agents in patients with diabetes and COVID-19: A Narrative Review [Diabetes Res Clin Pract, 2020]

Diabetes-related factors of glycemic control, medication pharmacodynamics, and insulin access can impact the severity of a COVID-19 infection.

... The coronavirus disease (COVID-19) is a global pandemic that significantly impacts people living with diabetes. Diabetes-related factors of glycemic control, medication pharmacodynamics, and insulin access can impact the severity of a COVID-19 infection. In this commentary, we explore how digital health can support the diabetes community through the ...

Ref: The Challenges of COVID-19 for People Living With Diabetes: Considerations for Digital Health [JMIR Diabetes, 2020-05-15]

Early-onset diabetes conferred an increased risk of hospitalization and obesity conferred an increased risk for ICU admission and intubation.

... we also found that obesity mediates 47.8% of the effect of diabetes on COVID-19 lethality. Early-onset diabetes conferred an increased risk of hospitalization and obesity conferred an increased risk for ICU admission and intubation. Our predictive score for COVID-19 lethality included age [≥]65 years, diabetes, diabetes & age <40 ...

Ref: Predicting mortality attributable to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico [JMIR Diabetes, 2020-04-24]

depression, anxiety, eating disorders and general stress compared with the general population [11, 12] .

... diabetes distress as well as an increased prevalence of a range of psychosocial problems, including depression, anxiety, eating disorders and general stress compared with the general population [11, 12] . The psychosocial consequences of the COVID-19 pandemic may add to the burden of psychosocial problems ...

Ref: Diabetes and COVID‐19: psychosocial consequences of the COVID‐19 pandemic in people with diabetes in Denmark—what characterizes people with high levels of COVID‐19‐related worries? [Diabet Med, 2020-05-29]

Microvascular and macrovascular diabetic complications were found in 46.8% and 40.8% of cases, respectively.

... median BMI 28.4 (25th-75th percentile: 25.0-32.7) kg/m2; with a predominance of type 2 diabetes (88.5%). Microvascular and macrovascular diabetic complications were found in 46.8% and 40.8% of cases, respectively. The primary outcome was encountered in 29.0% (95% CI 26.6, 31.5) of participants, while 10.6% ...

Ref: Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study [Diabetologia, 2020]

The other two important physiological links between diabetes and COVID-19 are liver dysfunction and chronic systemic inflammation.

... pathway indicates a higher risk for COVID-19 because of a dysregulation of Angiotensin-converting enzyme 2. The other two important physiological links between diabetes and COVID-19 are liver dysfunction and chronic systemic inflammation. A deep network analysis has suggested clinical biomarkers predicting the higher risk: Hypertension, elevated serum ...

Ref: Diabetes and metabolic syndrome as risk factors for COVID-19 [Diabetes Metab Syndr, 2020]

Diabetes in often associated with an increased severity and mortality in patients with COVID-19.

... BACKGROUND AND AIM: Diabetes in often associated with an increased severity and mortality in patients with COVID-19. We aimed to find out whether the severity and mortality in patients with diabetes with COVID-19 has any correlation to the level of glycemic control. METHODS: A ...

Ref: Does poor glucose control increase the severity and mortality in patients with diabetes and COVID-19? [Diabetes Metab Syndr, 2020]

diet, physical activity, medication taking and measurement of blood glucose.

... Changes in diabetes-related behaviours as a result of the COVID-19 pandemic were measured with a yes/no list of potential behaviour changes related to diet, physical activity, medication taking and measurement of blood glucose. ...

This potentially places patients with diabetes at additional risk of worsening hyperglycemia in case of a SARS-CoV2 infection,

... surprising that ACE-2 overexpression is further explored as a risk factor for COVID-19 [10] . This potentially places patients with diabetes at additional risk of worsening hyperglycemia in case of a SARS-CoV2 infection, and further supports the clinical evidence that T2DM constitutes a crucial risk factor for rapid ...

Ref: COVID-19 and diabetes: No time to drag our feet during an untimely pandemic() [J Diabetes Complications, 2020-05-15]

Many patients experienced increased blood glucose levels and need for higher insulin doses due to less physical activity and changed dietary habits.

... or child that were exposed to the virus, for example, through their work or peers. Many patients experienced increased blood glucose levels and need for higher insulin doses due to less physical activity and changed dietary habits. The Diabetes Association in collaboration with its experts issued statements about children with diabetes (not ...

Ref: Some Lessons Learned About Diabetes and COVID-19 During the Early Stage of the Epidemic in Norway [J Diabetes Sci Technol, 2020-05-26]

At the time of intercurrent illness, patients with diabetes are at a higher risk of developing 24 hyperglycemia

... At the time of intercurrent illness, patients with diabetes are at a higher risk of developing 24 hyperglycemia and therefore, more prone to the development of dehydration, diabetic 25 ketoacidosis (DKA) or Hyperosmolar hyperglycemic state (HHS). 4 Consequently, 26 pharmacists need to educate patients to help them manage ...

Ref: Caring for patients with diabetes during COVID-19 pandemic: Important considerations for pharmacists [Res Social Adm Pharm, 2020-05-31]

Diabetes could be a risk factor for severity and mortality in patients with coronavirus disease 2019 COVID-19.

... Diabetes could be a risk factor for severity and mortality in patients with coronavirus disease 2019 COVID-19. It has been hypothesized that DPP4 inhibition, a therapy currently available for type 2 diabetes, might represent a target for decreasing the risk of the acute respiratory complications of the ...

Ref: SARS-CoV-2 and DPP4 inhibition: Is it time to pray for Janus Bifrons? [Diabetes Res Clin Pract, 2020]

Diabetes and hyperglycemia are reported to exacerbate inflammation by increasing the release of tumor necrosis factor α (TNFα) and interleukin (IL) 10.

... 9 These epidemiological evidences indicate a critical role of diabetes in patients with severe covid-19. Diabetes and hyperglycemia are reported to exacerbate inflammation by increasing the release of tumor necrosis factor α (TNFα) and interleukin (IL) 10. [10] [11] [12] Clinical Care/Education/Nutrition In addition, diabetes may lead to lung dysfunction, such as ...

Ref: Clinical characteristics and outcomes of patients with severe covid-19 with diabetes [BMJ Open Diabetes Res Care, 2020-04-27]

Patients with diabetes had significantly higher leucocyte and neutrophil counts,

... were male. Common symptoms included fever (82.2%), dry cough (67.1%), polypnea (48.1%), and fatigue (38%). Patients with diabetes had significantly higher leucocyte and neutrophil counts, and higher levels of fasting blood glucose, serum creatinine, urea nitrogen and creatine kinase isoenzyme ...

Ref: Association of diabetes mellitus with disease severity and prognosis in COVID-19: A retrospective cohort study [Diabetes Res Clin Pract, 2020]

Diabetes mellitus (DM) is one of the most critical risk factors for complications and death in COVID-19 patients.

... BACKGROUND AND AIMS: Diabetes mellitus (DM) is one of the most critical risk factors for complications and death in COVID-19 patients. The present study aims to highlight challenges in the management of diabetic patients during the COVID-19 outbreak in developing countries. METHODS: We reviewed the literature to obtain ...

Ref: Challenges of diabetes care management in developing countries with a high incidence of COVID-19: A brief report [Diabetes Metab Syndr, 2020]

people with diabetes and its related comorbidities have increased risk for severe disease, and prolonged recovery and mortality.

... diabetes in low-income countries based on currently available data. The data is rapidly evolving; however, people with diabetes and its related comorbidities have increased risk for severe disease, and prolonged recovery and mortality. This review is also informed by data from severe acute respiratory syndrome (SARS) caused by ...

Ref: Glucovigilance in COVID-19. [JPMA. The Journal of the Pakistan Medical Association, 2020-05-01]

microvascular and macrovascular complications, mainly coronary heart disease) as well as pulmonary diseases (such as OSA).

... with younger individuals. In addition, these individuals also very frequently exhibited complications of diabetes ( microvascular and macrovascular complications, mainly coronary heart disease) as well as pulmonary diseases (such as OSA). As expected, they were also more frequently on insulin therapy and taking multiple drugs (such ...

Ref: Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study [Diabetologia, 2020-05-29]

Patients with diabetes and foot ulcers are at increased risk for infections, hospitalization, amputations, and death.

... disrupting the best practices for diabetic limb preservation, leaving large numbers of patients without care. Patients with diabetes and foot ulcers are at increased risk for infections, hospitalization, amputations, and death. Podiatric care is associated with fewer diabetes-related amputations, ER visits, hospitalizations, length-of-stay, and costs. But ...

Ref: All Feet On Deck-The Role of Podiatry During the COVID-19 Pandemic: Preventing hospitalizations in an overburdened healthcare system, reducing amputation and death in people with diabetes. [Journal of the American Podiatric Medical Association, 2020-03-25]

low-grade chronic inflammation with overproduction of proinflammatory cytokines, reduced natural killer cell number and activity, and impaired antigen-stimulation responses.

... increase the risk of complications from viral infections in obesity and type 2 diabetes, including low-grade chronic inflammation with overproduction of proinflammatory cytokines, reduced natural killer cell number and activity, and impaired antigen-stimulation responses. [15] [16] [17] Another factor that might have a role in the relationship between obesity, ...

Ref: Bariatric and metabolic surgery during and after the COVID-19 pandemic: DSS recommendations for management of surgical candidates and postoperative patients and prioritisation of access to surgery [Lancet Diabetes Endocrinol, 2020-05-07]

The major outcomes included in-hospital mortality, intensive care unit (ICU) admission, and invasive mechanical ventilation (IMV).

... HbA1c 5.7-6.4%), newly diagnosed diabetes (fasting glucose ≥7 mmol/L and/or HbA1c ≥6.5%), and known diabetes. The major outcomes included in-hospital mortality, intensive care unit (ICU) admission, and invasive mechanical ventilation (IMV). RESULTS: Patients with newly diagnosed diabetes had the highest percentage to be admitted to the ...

Ref: Newly diagnosed diabetes is associated with a higher risk of mortality than known diabetes in hospitalized patients with COVID-19 [Diabetes obes. metab, 2020]

severe pneumonia, release of tissue injury‐related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism.

... patients without other comorbidities but with diabetes (n = 24) were at higher risk of severe pneumonia, release of tissue injury‐related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism. Furthermore, serum levels of inflammation‐related biomarkers such as IL‐6, C‐reactive protein, serum ferritin and coagulation ...

Ref: Diabetes is a risk factor for the progression and prognosis of COVID‐19 [Diabetes Metab Res Rev, 2020-04-07]

Patients with frank hyperglycemia, dysglycemia and/or hyperinsulinemia develop systemic immunometabolic inflammation with higher levels of circulating cytokines.

... for prediabetic subjects with proinflammatory insulin resistance syndrome accompanied with prothrombotic hyperinsulinemic and dysglycemic states. Patients with frank hyperglycemia, dysglycemia and/or hyperinsulinemia develop systemic immunometabolic inflammation with higher levels of circulating cytokines. This deleterious scenario has been proposed as the underlying mechanism enhancing a cytokine storm-like hyperinflammatory ...

Ref: The COVID-19 Pandemic during the Time of the Diabetes Pandemic: Likely Fraternal Twins? [Pathogens, 2020-05-19]

79% of patients who died from COVID-19 had severe cardiovascular diseases, diabetes mellitus, neoplasms, renal diseases, respiratory disorders and obesity.

... old and older patients (38%). 85% of all deaths were over 50 years of age. 79% of patients who died from COVID-19 had severe cardiovascular diseases, diabetes mellitus, neoplasms, renal diseases, respiratory disorders and obesity. In total, co-morbidities (one or several) have been cardiovascular diseases (74%), diabetes mellitus (22%), lungs ...

Ref: COVID-19 IN DIABETES PATIENTS IN UKRAINE: LESSONS FOR DOCTORS AND PATIENTS. [Georgian medical news, 2020-04-01]

Group 2 patients have higher levels of LDH, prevalence of liver dysfunction and increased IL-8 than those in group 1,

... neutrophilia, lymphocytopenia, eosinopenia, and levels of sCRP, ferritin and d-dimer (P < 0.05 for all). Group 2 patients have higher levels of LDH, prevalence of liver dysfunction and increased IL-8 than those in group 1, a higher prevalence of increased IL-8 was found in group 2 than in group 3 ...

Ref: The Clinical Characteristics and Outcomes of Diabetes Mellitus and Secondary Hyperglycaemia Patients with Coronavirus Disease 2019: a Single-center, Retrospective, Observational Study in Wuhan [Diabetes obes. metab, 2020]

diabetes seems to be a risk factor which worsens the serious clinical events caused by COVID-19.

... According to previous reports, diabetes seems to be a risk factor which worsens the serious clinical events caused by COVID-19. But is diabetes per se a risk factor that increases the probability of getting the virus? This paper will discuss this point. There are not many ...

Ref: Diabetes and COVID-19 [Therapie, 2020]

Diabetes mellitus predisposes to a particularly severe course of the disease and doubles the COVID-19 mortality risk due to pulmonary and cardiac involvement.

... current pandemic of SARS-CoV‑2 coronavirus disease 2019 (COVID-19) is a particular challenge for diabetes patients. Diabetes mellitus predisposes to a particularly severe course of the disease and doubles the COVID-19 mortality risk due to pulmonary and cardiac involvement. In addition, diabetes patients often suffer from comorbidities which further worsen clinical outcomes. Glycemic control ...

Ref: Diabetes and COVID-19: Disease—Management—People [Wien Klin Wochenschr, 2020-05-20]

The intermingled effects of diabetes with other cardiovascular comorbidities warrant age-specific outcomes data including the impact of ongoing antidiabetic treatment.

... a pooled prevalence of 9.0% CONCLUSION: The overall prevalence of diabetes in COVID-19 patients was found to be 13.2% with studies including relatively elderly patients showing higher rates of diabetes. The intermingled effects of diabetes with other cardiovascular comorbidities warrant age-specific outcomes data including the impact of ongoing antidiabetic treatment. ...

Ref: COVID-19 and diabetes mellitus: A need for prudence in elderly patients from a pooled analysis [Diabetes Metab Syndr, 2020]

The second was to provide simple safe diabetes guidelines for use by specialists and non-specialists treating inpatients with or suspected of COVID-19 infection.

... call for re-deployment to support the need for general medical expertise across secondary care services. The second was to provide simple safe diabetes guidelines for use by specialists and non-specialists treating inpatients with or suspected of COVID-19 infection. To date the group, comprising UK-based specialists in diabetes, pharmacy and psychology, have produced two ...

Ref: Guidelines for the management of diabetes services and patients during the COVID-19 pandemic. [Diabetic medicine : a journal of the British Diabetic Association, 2020-05-04]

Patients with diabetes were more likely to have longer length of stay (LOS) in hospital, 14.4 (SD ±9.6) days,

... and 27.6 females, p = 0.016, with diabetes admitted to our hospital due to COVID-19. Patients with diabetes were more likely to have longer length of stay (LOS) in hospital, 14.4 (SD ±9.6) days, compared to the patients without diabetes, 9.8 (SD ±17.1) days, p < 0.0001. Patients with ...

Ref: Clinical characteristics and outcomes of COVID-19 hospitalized patients with diabetes in UK: A retrospective single centre study [Diabetes Res Clin Pract, 2020]

COVID-19 mostly manifests as mild upper respiratory disease and gastrointestinal disease, severe viral pneumonia with systemic organ failure, or even death.

... pneumonia. 3 The clinical symptoms of COVID-19 infection vary but mainly involve fever and cough. COVID-19 mostly manifests as mild upper respiratory disease and gastrointestinal disease, severe viral pneumonia with systemic organ failure, or even death. 4, 5 However, little attention has been paid to metabolic diseases caused by COVID-19, especially ...

Ref: COVID‐19 infection may cause ketosis and ketoacidosis [Diabetes Obes Metab, 2020-05-18]

hypertension, cardio-and cerebrovascular disease and chronic kidney disease

... diabetes with COVID-19, after conducting a 1:1 propensity score-matching (matched for other comorbidities that include hypertension, cardio-and cerebrovascular disease and chronic kidney disease ) and compared the outcomes of 250 patients with diabetes in each group. Notably, a ...

Ref: Does poor glucose control increase the severity and mortality in patients with diabetes and COVID-19? [Diabetes Metab Syndr, 2020-05-27]

Exclusion criteria were type-1 diabetes, immunotherapy for previous transplantation, and treatment of COVID-19 by corticotherapy or immunotherapy before inclusion.

... data are summarised in Table 1. COVID-19 diagnosis was based on positive oropharyngeal swab RT-PCR. Exclusion criteria were type-1 diabetes, immunotherapy for previous transplantation, and treatment of COVID-19 by corticotherapy or immunotherapy before inclusion. For the analysis, patients were divided into two groups: with or without T2D. Patients with ...

Ref: Monocyte class switch and hyperinflammation characterise severe COVID-19 in type 2 diabetes [Diabetes Metab Syndr, 2020-06-02]

severe pneumonia, release of tissue injury-related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism.

... patients without other comorbidities but with diabetes (n = 24) were at higher risk of severe pneumonia, release of tissue injury-related enzymes, excessive uncontrolled inflammation responses and hypercoagulable state associated with dysregulation of glucose metabolism. Furthermore, serum levels of inflammation-related biomarkers such as IL-6, C-reactive protein, serum ferritin and coagulation ...

Ref: Diabetes is a risk factor for the progression and prognosis of COVID-19 [Diabetes Metab Res Rev, 2020]

hypertension, cardiovascular disease, cerebrovascular disease or chronic pulmonary disease.

... did not differ significantly from non-survivors with diabetes in the prevalence of associated comorbidities including hypertension, cardiovascular disease, cerebrovascular disease or chronic pulmonary disease. Men with diabetes and severe covid-19 were more likely to die. In addition, non-survivors with ...

Ref: Diabetes and covid-19: a global health challenge [BMJ Open Diabetes Res Care, 2020-04-27]

Medical therapy for comorbidities ACEI/ARBs are essential in management of hypertension, heart failure and diabetic nephropathy.

... Medical therapy for comorbidities ACEI/ARBs are essential in management of hypertension, heart failure and diabetic nephropathy. Considering the contrasting effects of ACE2 on CoV infection and inflammatory lung injury (see above and Fig. 1 ), it is difficult to predict the possible clinical outcomes. To date, ...

Ref: cord_uid 15hqzcig Prevention and management of COVID-19 among pa... 15hqzcig Prevention and management of COVID-19 among pa... Name: title, dtype: object [BMJ Open Diabetes Res Care, cord_uid 15hqzcig 2020-05-14 15hqzcig 2020-05-14 Name: publish_time, dtype: object]

Risk, severity and mortality of the disease have been associated with non-communicable chronic diseases, such as diabetes mellitus.

... The coronavirus disease 2019 (covid-19) pandemic has caused a public health emergency worldwide. Risk, severity and mortality of the disease have been associated with non-communicable chronic diseases, such as diabetes mellitus. Accumulated evidence has caused great concern in countries with high prevalence of this morbidity, such as Brazil. ...

Ref: Diabetes and covid-19: more than the sum of two morbidities [Rev Saude Publica, 2020]

The complications due to Covid infection are also more in people having other co morbidities like hypertension and cardio vascular diseases.

... of developing complications due to the Covid infection than people who do not have diabetes. The complications due to Covid infection are also more in people having other co morbidities like hypertension and cardio vascular diseases. Due to the pandemic, there has been a tremendous change in the healthcare system. Basic ...

Ref: Coping with diabetes during the COVID – 19 lockdown in India: Results of an online pilot survey [Diabetes Metab Syndr, 2020-05-11]

Automatic consults for COVID-19 patients ensure that patients with serious illness receive specialized diabetes care.

... in the hospital is feasible and can provide similar outcomes to traditional face-to-face care. Conclusion: Automatic consults for COVID-19 patients ensure that patients with serious illness receive specialized diabetes care. Transitioning to virtual care models does not limit the glycemic outcomes of inpatient diabetes care ...

Ref: Inpatient Transition to Virtual Care During COVID-19 Pandemic [Diabetes Technol Ther, 2020]

Laparoscopic surgery involves aerosol-generating techniques such as carbon dioxide, pneumoperitoneum, electro cautery, and ultrasonic shearing.

... Laparoscopic surgery involves aerosol-generating techniques such as carbon dioxide, pneumoperitoneum, electro cautery, and ultrasonic shearing. These techniques could easily increase the risk of viral contagion for staff, 9, 10 including with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Upper gastrointestinal endoscopy (another aerosol-producing procedure) is ...

COVID-19 contributes to worsening of dysglycemia in people with diabetes mellitus over and above that contributed by stress hyperglycemia.

... Diabetes mellitus is associated with poor prognosis in patients with COVID-19. On the other hand, COVID-19 contributes to worsening of dysglycemia in people with diabetes mellitus over and above that contributed by stress hyperglycemia. Herein, we have reviewed the two-way interactions between COVID-19 and diabetes mellitus. METHODS: We have ...

Ref: COVID-19 and diabetes mellitus: An unholy interaction of two pandemics [Diabetes Metab Syndr, 2020]

Diabetes is a known risk factor for poorer outcome in patients who develop respiratory disease [28] ;

... Factor for Severe COVID-19. Diabetes is a known risk factor for poorer outcome in patients who develop respiratory disease [28] ; however, the association between diabetes and COVID-19 severity has not been examined systematically. We therefore performed a meta-analysis in order to examine the putative association between ...

Ref: Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-Analysis [Research (Wash D C), 2020-04-19]

Cardiovascular disease including coronary artery disease, congestive heart failure, or a history of myocardial infarction were included; reports of isolated hypertension were not included.

... Cardiovascular disease including coronary artery disease, congestive heart failure, or a history of myocardial infarction were included; reports of isolated hypertension were not included. Chronic pulmonary disease, chronic obstructive pulmonary disease (COPD), allergic airway disease or the use of supplemental oxygen at home was included. The presence of ARDS was designated by The berlin ...

Ref: Association of Diabetes Mellitus with Disease Severity and Prognosis in COVID-19: A Retrospective Cohort Study [Diabetes Res Clin Pract, 2020-05-22]

Several factors especially the impaired immune response, heightened inflammatory response and hypercoagulable state contribute to the increased disease severity.

... get coronavirus disease 2019 (COVID-19) are at risk of a severe disease course and mortality. Several factors especially the impaired immune response, heightened inflammatory response and hypercoagulable state contribute to the increased disease severity. However, there are many contentious issues about which the evidence is rather limited. There are ...

Ref: cord_uid 4ti8l2ea Diabetes and COVID-19: evidence, current statu... 4ti8l2ea Diabetes and COVID-19: evidence, current statu... Name: title, dtype: object [Diabetes Res Clin Pract, cord_uid 4ti8l2ea 2020-05-13 4ti8l2ea 2020-05-13 Name: publish_time, dtype: object]

ARDS, acute kidney injury, shock and hypoalbuminemia,

... admitted to the ICU and require IMV, had the highest prevalence of COVID-19-related complications including ARDS, acute kidney injury, shock and hypoalbuminemia, and also had the longest hospital stay, followed by patients with known diabetes and patients ...

Ref: Newly diagnosed diabetes is associated with a higher risk of mortality than known diabetes in hospitalized patients with COVID‐19 [Diabetes Obes Metab, 2020-05-29]

Diarrhea, mild abdominal pain, nausea, vomiting, poor appetite, and other symptoms were very common [26] .

... in addition to respiratory symptoms, gastrointestinal symptoms were the most in elderly patients with COVID-19. Diarrhea, mild abdominal pain, nausea, vomiting, poor appetite, and other symptoms were very common [26] . The involvement of the digestive tract had accelerated the occurrence of malnutrition in elderly patients ...

Ref: Prevalence of malnutrition and analysis of related factors in elderly patients with COVID-19 in Wuhan, China [Eur J Clin Nutr, 2020-04-22]

acute inflammatory response leads to insulin resistance and subsequent hyperglycemia which in turn necessitates intensification of pre-existing diabetes therapy [40] .

... impact of COVID-19 on glycemic control seems to be akin to other infectious disease states: acute inflammatory response leads to insulin resistance and subsequent hyperglycemia which in turn necessitates intensification of pre-existing diabetes therapy [40] . In a retrospective study from Wuhan, China, 56% out of 881 blood glucose measurements in ...

Ref: Diabetes and COVID-19: Disease—Management—People [Wien Klin Wochenschr, 2020-05-20]

Recent data showed that hypertension, diabetes mellitus, cardiovascular diseases, and chronic obstructive pulmonary disease were the most prevalent comorbidities in COVID-19 patients.

... a disease caused by a novel coronavirus SARS-CoV-2, is associated with significant morbidity and mortality. Recent data showed that hypertension, diabetes mellitus, cardiovascular diseases, and chronic obstructive pulmonary disease were the most prevalent comorbidities in COVID-19 patients. Additionally, data indicate that hypertension, diabetes, and cardiovascular diseases are important risk factors for progression ...

Ref: COVID-19 and diabetes: Is there enough evidence? [Journal of clinical hypertension, 2020-05-29]

Patients with COVID-19 need to be under surveillance for blood glucose screening.

... newly diagnosed diabetes had the highest risk of all-cause mortality compared with COVID-19 patients with known diabetes, hyperglycemia and normal glucose. Patients with COVID-19 need to be under surveillance for blood glucose screening. This article is protected by copyright. All rights reserved. ...

Ref: Newly diagnosed diabetes is associated with a higher risk of mortality than known diabetes in hospitalized patients with COVID-19 [Diabetes obes. metab, 2020]

Patients with an adrenal insufficiency are rare among patients entering the COVID-19 ward.

... Patients with an adrenal insufficiency are rare among patients entering the COVID-19 ward. However, one should not underestimate the hidden part of patients with a (partial) adrenal insufficiency. For instance, patients who used a high cumulative dose of steroids (in rheumatoid disease or ...

Ref: Diabetes or endocrinopathy admitted in the COVID‐19 ward [Eur J Clin Invest, 2020-05-24]

In-patient services need specialist support to appropriately manage glycaemia in people with known and undiagnosed diabetes presenting with COVID-19.

... with diabetes suffer disproportionately from acute COVID-19 with higher rates of serious complications and death. In-patient services need specialist support to appropriately manage glycaemia in people with known and undiagnosed diabetes presenting with COVID-19. Due to the restrictions imposed by the pandemic, people with diabetes may suffer longer-term harm ...

Ref: Endocrinology in the time of COVID-19: Remodelling Diabetes Services and Promoting Innovation. [European journal of endocrinology, 2020-06-05]

The inflammatory process associated with diabetes and chronic high levels of glucose in the blood can lead to low immunity response

The inflammatory process associated with diabetes and chronic high levels of glucose in the blood can lead to low immunity response which aggravate infections in patients with diabetes [2] .

Ref: Clinical characteristics and outcomes of COVID-19 hospitalized patients with diabetes in UK: A retrospective single centre study [Diabetes Res Clin Pract, 2020-06-10]

uncontrolled hyperglycemia

... higher percentage of death (41.7 vs. 14.8%, p<0.001) in patients with COVID-19 (n=184) who had uncontrolled hyperglycemia (defined as ≥2 blood glucose value, >180 mg/dl within any 24-hour period) but were not ...

Ref: Assessment of risk, severity, mortality, glycemic control and antidiabetic agents in patients with diabetes and COVID-19: A Narrative Review [Diabetes Res Clin Pract, 2020-06-11]

DM was associated with mortality, severe COVID-19, ARDS, and disease progression in patients with COVID-19.

... in prevalence of hypertension ≥25% (RR 1.93) compared to <25% (RR 3.06). Subgroup analysis on median age <55 years-old and prevalence of hypertension <25% showed strong association (RR 3.33) CONCLUSION: DM was associated with mortality, severe COVID-19, ARDS, and disease progression in patients with COVID-19. ...

Ref: Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia - A systematic review, meta-analysis, and meta-regression [Diabetes Metab Syndr, 2020]

there remain many grey areas and uncovered blind spots, some of which may apply to diabetic children.

... Although we are learning more about SARS-CoV-2 by the day, there remain many grey areas and uncovered blind spots, some of which may apply to diabetic children. It is essential that we keep ourselves updated on the continuous stream of information that may concern our patients. As ...

Ref: Caring for Pediatric Patients with Diabetes amidst the COVID-19 Storm [J Pediatr, 2020-05-05]

hypertension, diabetes mellitus, and other cardiovascular diseases being the most common [3] .

... infection to mild, and to critical illness [1, 2] . A significant portion of COVID-19 patients were reported to have at least one underlying complication when admitted to hospital, with hypertension, diabetes mellitus, and other cardiovascular diseases being the most common [3] . ...

Ref: Impact of Chronic Comorbidities on Progression and Prognosis in Patients with COVID-19: A Retrospective Cohort Study in 1031 Hospitalized Cases in Wuhan, China [J Pediatr, 2020-06-16]

hypertension, cardio-and cerebrovascular disease and chronic kidney disease)

... diabetes with COVID-19, after conducting a 1:1 propensity score-matching (matched for other comorbidities that include hypertension, cardio-and cerebrovascular disease and chronic kidney disease) and compared the outcomes of 250 patients with diabetes in each group. Notably, a significant ...

Ref: Does poor glucose control increase the severity and mortality in patients with diabetes and COVID-19? [Diabetes Metab Syndr, 2020-05-27]

patients with diabetes are at a higher risk of developing 24 hyperglycemia

Ref: Caring for patients with diabetes during COVID-19 pandemic: Important considerations for pharmacists [Res Social Adm Pharm, 2020-05-31]

Infection with COVID-19 is also generally associated with an increased insulin requirement [17] .

... Acute viral infection has previously been linked to the rapid development of transient insulin resistance [36] . Infection with COVID-19 is also generally associated with an increased insulin requirement [17] . ...

Ref: COVID-19: Impact of and on Diabetes [Diabetes Ther, 2020-06-06]

The objective of this study was to evaluate the influences of diabetes mellitus on the severity and fatality of SARS-CoV-2 infection.

... Diabetes mellitus is one of the most common comorbidities in Coronavirus disease 2019 (COVID-19) patients. The objective of this study was to evaluate the influences of diabetes mellitus on the severity and fatality of SARS-CoV-2 infection. MATERIALS AND METHODS Medical records of 66 hospitalized COVID-19 patients were collected and classified into ...

Ref: Influence of diabetes mellitus on the severity and fatality of SARS-CoV-2 infection. [Diabetes, obesity & metabolism, 2020-06-04]

Ensuring the availability of insulin, other medicines, selfmonitoring and diagnostic tools is another challenge,

... Ensuring the availability of insulin, other medicines, selfmonitoring and diagnostic tools is another challenge, both in terms of national supply and of distribution throughout countries during period of lockdown. In parallel affordability is of problem in all settings where people need to pay for ...

Ref: Beyond the virus: Ensuring continuity of care for people with diabetes during COVID-19 [Prim Care Diabetes, 2020-05-30]

diabetes is associated with structural changes to lung tissue including collapse of portions of the lung and altered permeability of the blood vessels in the lung [19] .

... Furthermore, diabetes is associated with structural changes to lung tissue including collapse of portions of the lung and altered permeability of the blood vessels in the lung [19] . This impact of diabetes on lung physiology and structure, in conjunction with the propensity of COVID-19 to infect lung tissue cells, may be contributing to increased mortality. ...

Ref: Mechanisms of increased morbidity and mortality of SARS-CoV-2 infection in individuals with diabetes: what this means for an effective management strategy [Metabolism, 2020-04-28]

Children with diabetes are also among the population susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

... Coronavirus disease 2019 (COVID-19) is the most serious public health problem in China. Children with diabetes are also among the population susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Traffic problems caused by epidemic prevention and control increase the difficulty in the management of children with ...

Ref: [Recommendations on the identification and transfer of children with critical diabetes during the COVID-19 outbreak]. [Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2020-04-01]

interference of comorbidities such as obesity and hypertension, and type of glucose-lowering therapy,

Ref: Prognostic factors in patients with diabetes hospitalized for COVID-19: Findings from the CORONADO study and other recent reports [Diabetes Metab, 2020-05-21]

anxiety and sleep disturbances may adversely affect glucose control.

... insulin, due to unexpected delays to their travels and difficulty in gaining access to medications. Another contagion that has occurred as a result of COVID-19 is fear, and the resulting anxiety and sleep disturbances may adversely affect glucose control. ...

Ref: COVID‐19 and diabetes [Diabet Med, 2020-04-03]

Chronic inflammation, increased coagulation activity, immune response impairment, and potential direct pancreatic damage by SARS-CoV-2

... Older age, diabetes and other comorbidities are reported as significant predictors of morbidity and mortality. Chronic inflammation, increased coagulation activity, immune response impairment, and potential direct pancreatic damage by SARS-CoV-2 might be among the underlying mechanisms of the association between diabetes and COVID-19. No conclusive ...

Ref: COVID-19 and diabetes: Knowledge in progress [Diabetes Res Clin Pract, 2020]

Cardiovascular disease included coronary artery disease, congestive heart failure, or a history of myocardial infarction; reports of isolated hypertension were not included.

Ref: Comorbid Diabetes Mellitus was Associated with Poorer Prognosis in Patients with COVID-19: A Retrospective Cohort Study [Diabetes Res Clin Pract, 2020-03-26]

The diabetic COVID-19 patients had the highest proportions of comorbidities such as hypertension and cardiovascular disease,

... high rates of severe and critical cases and high mortality in COVID-19 patients with diabetes. The diabetic COVID-19 patients had the highest proportions of comorbidities such as hypertension and cardiovascular disease, among the three groups, and the prevalence of cardiovascular disease was almost statistically significant, possibly ...

Ref: The Clinical Characteristics and Outcomes of Diabetes Mellitus and Secondary Hyperglycaemia Patients with Coronavirus Disease 2019: a Single‐center, Retrospective, Observational Study in Wuhan [Diabetes Obes Metab, 2020-05-14]

Moreover, COVID-19 infection can also present with digestive symptoms such as vomiting and diarrhea leading to dehydration.

... symptoms of COVID-19 and predispose to acute metabolic complications, such as ketoacidosis and hyperosmolar coma. Moreover, COVID-19 infection can also present with digestive symptoms such as vomiting and diarrhea leading to dehydration. According to a Chinese study including 29 T2DM patients, hyperglycemia was frequent over the course ...

Ref: COVID-19 in diabetic patients: related risks and specifics of management [Ann Endocrinol (Paris), 2020-05-12]

Diabetes induces a chronic systemic inflammation, which regularly manifests as periodontitis.

... diabetes patients. The immune system of people with diabetes is considered to be generally impaired. Diabetes induces a chronic systemic inflammation, which regularly manifests as periodontitis. Furthermore, frequent hyperglycaemia is known to lead to additional weakening of the oral mucosa barrier. ...

Ref: Why Do People With Diabetes Have a High Risk for Severe COVID-19 Disease?-A Dental Hypothesis and Possible Prevention Strategy. [Journal of diabetes science and technology, 2020-06-07]

Epidemiology studies suggest that comorbid diabetes may have negative impact on the progression and severity of the coronavirus disease 2019 (COVID-19),

... Epidemiology studies suggest that comorbid diabetes may have negative impact on the progression and severity of the coronavirus disease 2019 (COVID-19), which first occurred in Wuhan However, the exact mechanism remains unclear A recent study on another type of coronavirus infection, Middle East Respiratory Syndrome (MERS), investigated its relationship with diabetes ...

Ref: Use Stones from Another Mountain to Polish One’s Jade: Learn from MERS Studies toexplore potential mechanisms underlying the effect of diabetes mellitus on COVID-19 [Chinese Journal of Endocrinology and Metabolism, 2020]

Use of insulin pumps and continuous glucose monitoring appeared as an effective way to prevent the risk of acute metabolic complications related to the changes of daily life

... epidemic in patients with type 1 diabetes using diabetes technology in the South of France. Use of insulin pumps and continuous glucose monitoring appeared as an effective way to prevent the risk of acute metabolic complications related to the changes of daily life associated with requested confinement . Care by telemedicine was facilitated in these patients who used ...

Ref: Personal Experience With COVID-19 and Diabetes in the South of France: Technology Facilitates the Management of Diabetes in Disruptive Times [J Diabetes Sci Technol, 2020]

diabetic patients do not appear to be at increased risk of contracting SARS-CoV-2 compared to the general population.

... among the most frequently reported comorbidities in patients infected with COVID-19. According to current data, diabetic patients do not appear to be at increased risk of contracting SARS-CoV-2 compared to the general population. On the other hand, diabetes is a risk factor for developing severe and critical forms ...

Ref: COVID-19 in diabetic patients: Related risks and specifics of management [Ann Endocrinol (Paris), 2020]

diabetes mellitus, smoking, stroke has also been associated with fatal outcome [9] .

... hypertension recognized as the most common while risk factors associated with cardiovascular disease (CVD) i.e. diabetes mellitus, smoking, stroke has also been associated with fatal outcome [9] . Indeed, in patients with severe course of the COVID-19 with life threatening pneumonia in need ...

Ref: Diabetes mellitus: Lessons from the COVID-19 pandemic [Hellenic J Cardiol, 2020-05-18]

diabetes mellitus, obesity, arterial hypertension, ACE-inhibitors, cytokine storm, immune response and vitamin D.

... until April 23, 2020 using the keywords COVID-19, SARS-CoV-2, treatment of coronavirus and following terms: diabetes mellitus, obesity, arterial hypertension, ACE-inhibitors, cytokine storm, immune response and vitamin D. RESULTS: Studies indicate that obese individuals are more likely to develop infections, and that adipose ...

Ref: Mechanism of inflammatory response in associated comorbidities in COVID-19 [Diabetes Metab Syndr, 2020-05-12]

overweight and obesity, systemic arterial hypertension, atherogenic dyslipidemia and in some patients peripheral vascular disease, kidney damage, neuropathy and retinopathy.

... coronary artery disease is the leading cause of death. The comorbidities associated with diabetes are overweight and obesity, systemic arterial hypertension, atherogenic dyslipidemia and in some patients peripheral vascular disease, kidney damage, neuropathy and retinopathy. Chronic lack of control of the disease is associated with increased susceptibility to infections, which ...

Ref: Coronavirus infection in patients with diabetes. [Archivos de cardiologia de Mexico, 2020]

Interleukin-6 (IL-6), which is already increased in conditions of chronic inflammation,

... Covid-19. Among different cytokines found significantly higher in patients with diabetes compared to those without, Interleukin-6 (IL-6), which is already increased in conditions of chronic inflammation, may play a more deleterious role in Covid-19 infection. Targeting the overexpression of Il-6 effects ...

Ref: Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics [Diabetes Metab Res Rev, 2020]

Common symptoms included fever (82.2%), dry cough

... with COVID-19, the median age was 64 years (range 23-91), and 138 (53.5%) were male. Common symptoms included fever (82.2%), dry cough (67.1%), polypnea (48.1%), and fatigue (38%). Patients with diabetes had significantly higher leucocyte and neutrophil ...

Ref: Association of diabetes mellitus with disease severity and prognosis in COVID-19: A retrospective cohort study [Diabetes Res Clin Pract, 2020]

risk of ARDS, ICU requirement, and invasive ventilatory requirement,

... low heterogeneity (I 2 =32%). In addition, diabetes mellitus was associated with severe COVID-19, including risk of ARDS, ICU requirement, and invasive ventilatory requirement, with a pooled odds ratio of 2.75 (95% CI: 2.09-3.62; p<0.01). The combined pooled odds ...

Ref: Is diabetes mellitus associated with mortality and severity of COVID-19? A meta-analysis [Diabetes Metab Syndr, 2020-05-06]

Glycemic control during infectious diseases is often suboptimal, and antidiabetic drugs and insulin therapy have to be adapted accordingly.

... cardiac involvement. In addition, diabetes patients often suffer from comorbidities which further worsen clinical outcomes. Glycemic control during infectious diseases is often suboptimal, and antidiabetic drugs and insulin therapy have to be adapted accordingly. On the other hand, access of diabetes patients to outpatient clinics are limited during the ...

Ref: Diabetes and COVID-19: Disease—Management—People [Wien Klin Wochenschr, 2020-05-20]

This necessitates increased vigilance and testing in outpatient diabetes and general medicine clinics for COVID-19 and a lower threshold for hospitalization of these patients.

... increased risk for COVID-19 infection, and are at increased risk for medical complications including death. This necessitates increased vigilance and testing in outpatient diabetes and general medicine clinics for COVID-19 and a lower threshold for hospitalization of these patients. In this regard, an unreported disturbing observation by the authors is that an increasing number ...

Ref: Commentary: COVID-19 in patients with diabetes [Metabolism, 2020-03-24]

Patients with diabetes were more likely to have longer length of stay (LOS) in hospital,

Ref: Clinical characteristics and outcomes of COVID-19 hospitalized patients with diabetes in UK: A retrospective single centre study [Diabetes Res Clin Pract, 2020]

Type I diabetes is an autoimmune disease characterized by an antibody-mediated attack on islet cells.

... by long-standing immune system imbalance." This perhaps suggests all the patients had type 2 disease. Type I diabetes is an autoimmune disease characterized by an antibody-mediated attack on islet cells. Type 2, as referenced in the manuscript, has increased release of inflammatory factors and chemokines. ...

Ref: In response: Diabetes is a risk factor for the progression and prognosis of COVID‐19 [Diabetes Metab Res Rev, 2020-05-26]

a cytokine storm that showed greatly elevated levels of inflammatory cytokines has been implicated in the multi-organ failure in patients with severe diseases.

... state of metabolic inflammation that predisposes them to an enhanced release of cytokines. For COVID-19, a cytokine storm that showed greatly elevated levels of inflammatory cytokines has been implicated in the multi-organ failure in patients with severe diseases. 29 Metabolic inflammation caused by hyperglycemia can also damage the immune system, reducing the body"s ...

Ref: Newly diagnosed diabetes is associated with a higher risk of mortality than known diabetes in hospitalized patients with COVID‐19 [Diabetes Obes Metab, 2020-05-29]

Individuals with diabetes are at risk of infections, especially influenza and pneumonia.

... Individuals with diabetes are at risk of infections, especially influenza and pneumonia. This risk can be reduced, though not completely eliminated, by good glycaemic control. All people with diabetes (above 2 years of age) are recommended pneumococcal and annual influenza vaccinations. Not ...

Ref: Clinical considerations for patients with diabetes in times of COVID-19 epidemic [Diabetes Metab Syndr, 2020-03-10]

People with type 2 diabetes mellitus (T2DM) have increased morbidity and mortality due to coronavirus disease-19(COVID-19).

... BACKGROUND AND AIMS People with type 2 diabetes mellitus (T2DM) have increased morbidity and mortality due to coronavirus disease-19(COVID-19). It has been speculated that use of pioglitazone might increase such risk. The aim of our brief commentary is to review the safety of pioglitazone in people ...

Ref: Use of pioglitazone in people with type 2 diabetes mellitus with coronavirus disease 2019 (COVID-19): Boon or bane? [Diabetes & metabolic syndrome, 2020-06-10]

Older age and presence of diabetes mellitus, hypertension, and obesity significantly increases the risk for hospitalization and death in COVID-19 patients.

... a disease caused by a novel coronavirus (CoV), SARS-CoV-2, is causing substantial morbidity and mortality. Older age and presence of diabetes mellitus, hypertension, and obesity significantly increases the risk for hospitalization and death in COVID-19 patients. In this Perspective, informed by the studies on severe acute respiratory syndrome, SARS-CoV, and Middle ...

Ref: COVID-19 Pandemic, Corona Viruses, and Diabetes Mellitus. [American journal of physiology. Endocrinology and metabolism, 2020-03-31]

Acute diabetes complication like DKA increases morbidity and mortality in addition to adding cost to the health care system.

... most of the education was done remotely by certified diabetes care and education specialists. Conclusion: Acute diabetes complication like DKA increases morbidity and mortality in addition to adding cost to the health care system. The current pandemic of COVID-19 has allowed newer ways (with the help of newer technologies) ...

Ref: The Silver Lining to COVID-19: Avoiding Diabetic Ketoacidosis Admissions with Telehealth. [Diabetes technology & therapeutics, 2020-05-05]