¿Cuáles son los primeros sintomas del Covid-19?

(What are the initial symptoms of covid-19?)


Primeras 5 respuestas:

  1. The initial CT imaging manifestations are mainly peripheral or subpleural ground-glass opacities and ground-glass with consolidation.

  2. fever, cough and shortness of breath.

  3. The early symptoms were fever, sore throat, cough or sputum production, chills, and muscle ache.

  4. The main symptom of patients was fever, and secondary symptoms included cough, expectoration, dizziness, nasal congestion, and myalgia.

  5. Fever, dry cough, and fatigue are common symptoms of COVID-19 pneumonia.



The initial CT imaging manifestations are mainly peripheral or subpleural ground-glass opacities and ground-glass with consolidation.

... patient was negative before the onset of symptoms. Two asymptomatic patients had typical CT abnormalities. The initial CT imaging manifestations are mainly peripheral or subpleural ground-glass opacities and ground-glass with consolidation. Our report is of potential guiding value for the initial CT screening of imported familial ...

Ref: Initial CT imaging characters of an imported family cluster of COVID-19 [Clin Imaging, 2020-04-22]


fever, cough and shortness of breath.

... Disease Control guidelines, has relied on three necessary symptoms in making the diagnosis of COVID-19: fever, cough and shortness of breath. We present four cases of elderly patients who developed altered mental status as their presenting ...

Ref: Altered Mental Status as a Novel Initial Clinical Presentation for COVID-19 Infection in the Elderly [Am J Geriatr Psychiatry, 2020-05-15]


The early symptoms were fever, sore throat, cough or sputum production, chills, and muscle ache.

... patients), Zhuhai, China, (1 patient), Singapore (2 patients), Japan (1 patient), and Thailand (1 patient). The early symptoms were fever, sore throat, cough or sputum production, chills, and muscle ache. Three patients were asymptomatic, however, 18 developed pneumonia. Of the 28 cases, 16 were index ...

Ref: Early Epidemiological and Clinical Characteristics of 28 Cases of Coronavirus Disease in South Korea [Osong Public Health Res Perspect, 2020-02-19]


The main symptom of patients was fever, and secondary symptoms included cough, expectoration, dizziness, nasal congestion, and myalgia.

... of SARS-CoV-2 exposure, in the absence of medical staff or family clusters of SARS-CoV-2 infection. The main symptom of patients was fever, and secondary symptoms included cough, expectoration, dizziness, nasal congestion, and myalgia. According to the changes in this disease over time [10, 11] , in our study, ...

Ref: Coronavirus disease 2019: initial chest CT findings [Eur Radiol, 2020-03-24]


Fever, dry cough, and fatigue are common symptoms of COVID-19 pneumonia.

... an adolescent, aged 17. The main clinical manifestations of COVID-19 pneumonia are acute respiratory symptoms. Fever, dry cough, and fatigue are common symptoms of COVID-19 pneumonia. In severe cases, dyspnea or hypoxemia develops, which may rapidly progress to acute respiratory distress ...

Ref: Imaging characteristics of initial chest computed tomography and clinical manifestations of patients with COVID-19 pneumonia [Jpn J Radiol, 2020-04-21]


The first phase was characterised by fever, cough, fatigue and other systemic symptoms.

... The clinical progression of COVID-19 in our patients showed a biphasic pattern. The first phase was characterised by fever, cough, fatigue and other systemic symptoms. In consistent with previous studies, we found that fever was the most common symptom in patients with COVID-19. ...

Ref: Clinical progression of patients with COVID-19 in Shanghai, China [J Infect, 2020-03-19]


Nasal congestion, myalgia, headache, chills, fever, fatigue, and coughing were common initial symptoms,

... author/funder, who has granted medRxiv a license to display the preprint in perpetuity. Nasal congestion, myalgia, headache, chills, fever, fatigue, and coughing were common initial symptoms, whereas gastrointestinal tract symptoms were rare initial symptoms. In this study, 5 (2.4%) patients had an initial ...

Ref: Gastrointestinal tract symptoms in coronavirus disease 2019: Analysis of clinical symptoms in adult patients [J Infect, 2020-03-27]


fever, dry cough, sore throat, fatigue, diarrhea, conjunctivitis, hyposmia, and hypogeusia.

... reservoir. 4 Incubation time of COVID-19 is up to 14 days. Typical clinical symptoms include fever, dry cough, sore throat, fatigue, diarrhea, conjunctivitis, hyposmia, and hypogeusia. Diagnosis is based on medical and travel history, contact to COVID-19 patients, and clinical symptoms. ...

Ref: Cutaneous signs in COVID‐19 patients: A review [Dermatol Ther, 2020-05-29]


fever, cough, rhinorrhea, chest pain, diarrhea, vomiting, nausea, confusion, etc.

... biggest health concern worldwide. COVID-19 may accompany a wide range of signs and symptoms including fever, cough, rhinorrhea, chest pain, diarrhea, vomiting, nausea, confusion, etc. Whereas, some patients may be asymptomatic [6] . The diagnosis of COVID-19 is made through ...

Ref: The neurological manifestations of COVID-19: a review article [Neurol Sci, 2020-06-01]


cough, shortness of breath, and sore throat.

... OBJECTIVES: Coronavirus disease 2019 (COVID-19) most commonly presents with respiratory symptoms, including cough, shortness of breath, and sore throat. However, digestive symptoms also occur in patients with COVID-19 and are often described in outpatients with less severe ...

Ref: Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes [Am J Gastroenterol, 2020-04-15]


The typical clinical manifestations were fever, cough, dyspnea, and myalgia or fatigue.

... novel betacoronavirus called 2019 novel coronavirus (officially named by the World Health Organization as COVID-19). The typical clinical manifestations were fever, cough, dyspnea, and myalgia or fatigue. Less common symptoms included headache, diarrhea, nausea and vomiting. However diarrhea as the first symptom ...

Ref: A case of COVID-19 patient with the diarrhea as initial symptom and literature review [Clin. res. hepatol. gastroenterol, 2020]


Fever (92%), cough (60%) and fatigue (56%) were the most common symptoms.

... days. Ninety-two percent of patients had respiratory symptoms, and 8% of them had digestive symptoms. Fever (92%), cough (60%) and fatigue (56%) were the most common symptoms. Most patients had a normal or reduced WBC (96%), reduced lymphocyte count (60%), increased CRP ...

Ref: A retrospective study of the initial 25 COVID-19 patients in Luoyang, China [Jpn. j. radiol. (Internet), 2020]


The main clinical symptoms of COVID-19 are fever, fatigue, and a dry cough.

... country. Highly infectious, COVID-19 has numerous transmission channels and humans are highly susceptible to infection. The main clinical symptoms of COVID-19 are fever, fatigue, and a dry cough. Laboratory examination in the early stage of the disease shows a normal or decreased white ...

Ref: Clinical and imaging features of COVID-19 [Radiol Infect Dis, 2020-04-27]


Common symptoms include fever, cough and myalgia or fatigue.

Understanding the clinical symptoms of COVID-19 is important, although the clinical symptoms are indicated nonspecific. Common symptoms include fever, cough and myalgia or fatigue.

Ref: Coronavirus Disease 2019 (COVID-19): A Perspective from China [Radiology, 2020-02-21]


Two such candidate symptoms include anecdotally reported loss of smell and taste.

... underline the importance of identifying early or subclinical symptoms of coronavirus disease 2019 (COVID-19) infection. Two such candidate symptoms include anecdotally reported loss of smell and taste. Understanding the timing and association of smell/taste loss in COVID-19 may help facilitate screening and ...

Ref: Association of chemosensory dysfunction and COVID-19 in patients presenting with influenza-like symptoms [Int. forum allergy rhinol, 2020]


fever, a dry cough, shortness of breath, myalgia or fatigue, and dyspnea.

... most common signs and symptoms of the 2019 novel coronavirus (COVID-19; temporarily termed as 2019-nCoV) at onset are fever, a dry cough, shortness of breath, myalgia or fatigue, and dyspnea. Owing to the complexity of COVID-19, some patients may present with atypical ...

Ref: 2019 Novel Coronavirus (COVID-19) Pneumonia with Hemoptysis as the Initial Symptom: CT and Clinical Features [Korean J Radiol, 2020-03-13]


Having initial clinical symptoms, fever being the most common is the main reason for visiting the ED.

... Having initial clinical symptoms, fever being the most common is the main reason for visiting the ED. 15 In our study, fever and cough were the most common symptoms observed in all patients with suspected disease. Due to the high seasonal incidence of respiratory diseases, these were ...

Ref: Initial clinical features of suspected coronavirus disease 2019 in two emergency departments outside of Hubei, China [J Med Virol, 2020-03-24]


Common presenting symptoms for patients with confirmed infection include fever, cough, and myalgia and fatigue [1] [2] [3] .

... Common presenting symptoms for patients with confirmed infection include fever, cough, and myalgia and fatigue [1] [2] [3] . Typical laboratory findings on admission include normal leucocytes in majority of patients and decreased lymphocytes in 35% of patients [2] . According to published reports, common CT findings consist of ...

Ref: Evolution of CT findings in patients with mild COVID-19 pneumonia [Eur Radiol, 2020-04-15]


First, most of them (70%) had mild or no respiratory signs at the time of stroke,

... new important insights into patients with COVID-19 who suffer from AIS due to an LVO. First, most of them (70%) had mild or no respiratory signs at the time of stroke, which could suggest the absence of correlation between the severity of respiratory symptoms and the ...

Ref: Treatment of Acute Ischemic Stroke due to Large Vessel Occlusion With COVID-19: Experience From Paris [Stroke, 2020-06-08]


disrupted taste and flavour perception prior to respiratory involvement.

... of COVID-19 resulting in intensive care unit (ICU) admission, presenting with the initial symptom of disrupted taste and flavour perception prior to respiratory involvement. After 4 days in the ICU and 6 days on the general medicine floor, our ...

Ref: Hypogeusia as the initial presenting symptom of COVID-19 [BMJ Case Rep, 2020-05-13]


COVID-19 typically presents with fever and respiratory symptoms including dry cough and dyspnea.

... COVID-19 typically presents with fever and respiratory symptoms including dry cough and dyspnea. The elderly population is more likely to develop severe disease complications, especially those with comorbidities such as hypertension, diabetes mellitus, and chronic obstructive pulmonary disease (COPD). However, neurological manifestations of ...

Ref: Neurological manifestations of COVID-19: a review of what we know so far [J Neurol, 2020-05-26]


Symptoms considered in the review included respiratory, gastrointestinal (e.g., diarrhea), and constitutional symptoms.

... onset occurring after the date of exposure to the secondary patient who was subsequently infected. Symptoms considered in the review included respiratory, gastrointestinal (e.g., diarrhea), and constitutional symptoms. In addition, the source patient"s exposure had to be strongly attributed epidemiologically to transmission from ...

Ref: Presymptomatic Transmission of SARS-CoV-2 — Singapore, January 23–March 16, 2020 [MMWR Morb Mortal Wkly Rep, 2020-04-10]


Diarrhea; Nausea; Vomiting; Abdominal Pain; Belching; Anorexia.

... conducted in Medline using the words COVID-19 AND Gastrointestinal symptoms: AND with specific symptoms including Diarrhea; Nausea; Vomiting; Abdominal Pain; Belching; Anorexia. Afterwards, we combined the descriptor COVID-19 AND China; South Korea; Italy; Europe; North America; United ...

Ref: Beware: Gastrointestinal symptoms can be a manifestation of COVID-19 [Rev Gastroenterol Mex, 2020-04-15]


fever, cough, and myalgia or fatigue, with or without sputum production and diarrhea.

... most common clinical characteristics of patients with COVID-19 at the onset of illness manifested as fever, cough, and myalgia or fatigue, with or without sputum production and diarrhea. 7 Therefore, detecting and confirming infected cases in a timely manner and applying scientific treatment ...

Ref: Caution: The clinical characteristics of COVID-19 patients at admission are changing [Rev Gastroenterol Mex, 2020-03-06]


The patient first experienced a fever of 100.8°F and fatigue, both lasting 8 days.

... contracted as the patient did not have an exposure to a patient with known COVID-19. The patient first experienced a fever of 100.8°F and fatigue, both lasting 8 days. The day after fever onset, the patient developed shortness of breath, which lasted 7 days. ...

Ref: Novel Coronavirus Disease (COVID-19) and Biologic Therapy for Psoriasis: Successful Recovery in Two Patients After Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) [Dermatol Ther (Heidelb), 2020-05-29]


fever, respiratory, and gastrointestinal symptoms as well as shedding of virus RNA into feces.

... Abstract Background & Aims Infection with SARS-CoV-2 causes COVID-19, which has been characterized by fever, respiratory, and gastrointestinal symptoms as well as shedding of virus RNA into feces. We performed a systematic review and meta-analysis of published gastrointestinal symptoms and detection of virus in ...

Ref: Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis [Gastroenterology, 2020-04-03]


the first symptom and imaging features of patients can be very atypical and early diagnosis of COVID-19 infections remains a challenge.

... viral infection, resulting in no traceable epidemiological history. Owing to the complications of COVID-19 pneumonia, the first symptom and imaging features of patients can be very atypical and early diagnosis of COVID-19 infections remains a challenge. It would aid radiologists and clinicians to be aware of the early atypical symptom and ...

Ref: 2019 Novel Coronavirus (COVID-19) Pneumonia with Hemoptysis as the Initial Symptom: CT and Clinical Features [Korean J Radiol, 2020]


The majority of COVID-19 cases are mild.

... CONCLUSIONS: The majority of COVID-19 cases are mild. The clinical progression pattern suggests that early control of viral replication and application of host-directed therapy in later stage is essential to improve the prognosis of CVOID-19. ...

Ref: Clinical progression of patients with COVID-19 in Shanghai, China [J Infect, 2020]


Nonspecific symptoms such as myalgias (17.2%), headache (14.1%), and dizziness

... with COVID-19 (mean age 66.4 years, 56.2% men) 57.4% developed some form of neurological symptom. Nonspecific symptoms such as myalgias (17.2%), headache (14.1%), and dizziness (6.1%) were present mostly in the early stages of infection. Anosmia (4.9%) and dysgeusia (6.2%) ...

Ref: Neurologic manifestations in hospitalized patients with COVID-19: The ALBACOVID registry [Neurology, 2020]


Respiratory rate was 17, pulse rate was 93, fever was 38°C, and blood oxygen saturation was 95% in ambient air.

... healthy and had an active lifestyle. The patient reported symptoms starting from 3 days earlier. Respiratory rate was 17, pulse rate was 93, fever was 38°C, and blood oxygen saturation was 95% in ambient air. A chest CT scan was obtained from the patient which showed nonspecific findings (few linear ...

Ref: Rapidly progressive COVID-19 viral pneumonia: a report of two patients with a focus on imaging findings [Egypt J Radiol Nucl Med, 2020-06-16]


fever, cough, and shortness of breath [12] .

... Control and Prevention, screening for COVID-19 should be based on the presence of symptoms of fever, cough, and shortness of breath [12] . The most common symptom in patients diagnosed with COVID-19 was fever (84.8%; 95% CI, 78.5% ...

Ref: The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis [Clin Exp Otorhinolaryngol, 2020-05-01]


Patients in the initial incubation phase often have insidious clinical symptoms, but they are still highly contagious.

... runs its course in two phases, the initial incubation phase and later clinical symptomatic phase. Patients in the initial incubation phase often have insidious clinical symptoms, but they are still highly contagious. At the later clinical symptomatic phase, the immune system is fully activated and the disease ...

Ref: Clinical time course of COVID-19, its neurological manifestation and some thoughts on its management [Clin Exp Otorhinolaryngol, 2020]


presenting with the initial symptom of disrupted taste and flavour perception prior to respiratory involvement.

... olfactory dysfunction. We present a case of COVID-19 resulting in intensive care unit (ICU) admission, presenting with the initial symptom of disrupted taste and flavour perception prior to respiratory involvement. After 4 days in the ICU and 6 days on the general medicine floor, our ...

Ref: Hypogeusia as the initial presenting symptom of COVID-19 [BMJ Case Rep, 2020-05-13]


symptoms (e.g., cough, sore throat, fever).

... ACE2, and the pathogenic mechanism might probably be shared between SARS-CoV and COVID-19 [29] . symptoms (e.g., cough, sore throat, fever). For all suspected cases that are undergoing operation, chest CT and blood tests need to ...

Ref: Diagnosis and treatment of coronavirus disease 2019 (COVID-19): Laboratory, PCR, and chest CT imaging findings [Int J Surg, 2020-05-15]


fever, fatigue, and breath-dependent chest pain.

... the patient was admitted to one of our specialized COVID-19 wards with aggravating symptoms including fever, fatigue, and breath-dependent chest pain. Urinary frequency is a common symptom in urinary infection. In order to investigate if this ...

Ref: Urinary Frequency as a Possibly Overlooked Symptom in COVID-19 Patients: Does SARS-CoV-2 Cause Viral Cystitis? [Eur Urol, 2020-05-19]


Records showed that common symptoms include fever and respiratory symptoms including dry cough and sore throat.

... al., 2020; Shi et al., 2020; Song et al., 2020; Wang et al., 2020) . Records showed that common symptoms include fever and respiratory symptoms including dry cough and sore throat. Laboratory test results showed that lymphopenia is present in most cases and that lung abnormalities ...

Ref: Initial chest CT findings in COVID-19: correlation with clinical features [J Zhejiang Univ Sci B, 2020-05-20]


• Multiple GGOs with consolidations in the periphery of the lungs were the primary CT characteristic of COVID-19.

... are found, then the differential diagnosis of coronavirus disease 2019 must be considered. KEY POINTS: • Multiple GGOs with consolidations in the periphery of the lungs were the primary CT characteristic of COVID-19. • The halo sign may be a special CT feature in the early-stage COVID-19 patients. ...

Ref: Coronavirus disease 2019: initial chest CT findings [Eur. radiol, 2020]


On illness days 6 to 10, she remained afebrile with minimal cough and clear breath sounds.

... On illness days 6 to 10, she remained afebrile with minimal cough and clear breath sounds. During this time, real-time PCR for detecting SARS-CoV-2 was established at the RITM using the Corman et al. protocol [7] . Further NPS/OPS specimens collected on January 29 (reported on ...

Ref: First COVID-19 infections in the Philippines: a case report [Trop Med Health, 2020-04-14]


In the early-stage (0-3 days), the percentage of lung involvement was 4%,

... parameters showed to have a relationship with the time from symptom onset to initial CT. In the early-stage (0-3 days), the percentage of lung involvement was 4%, with a mean density of - 462 ± 99 HU. The peak density of lesions ...

Ref: Lung involvement in patients with coronavirus disease-19 (COVID-19): a retrospective study based on quantitative CT findings [Chin J Acad Radiol, 2020]


fever (13/15 patients) and cough (9/15 patients).

... for all patients. The most common onset symptoms of COVID-19 pneumonia in pregnant women were fever (13/15 patients) and cough (9/15 patients). The most common abnormal laboratory finding was lymphocytopenia (12/15 patients). CT images obtained before and ...

Ref: Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis [AJR Am J Roentgenol, 2020]


anosmia and dysgeusia [6] .

... multicenter study in Europe, as many as 85.6% and 88.0% of mild-to-moderate COVID-19 patients showed anosmia and dysgeusia [6] . These symptoms preceded other symptoms in 11.8% of patients and were not accompanied by symptoms ...

Ref: Does the Clinical Spectrum of Coronavirus Disease 2019 (COVID-19) Show Regional Differences? [Clin Exp Otorhinolaryngol, 2020-05-08]


non-chest CT scans that may uncover unsuspected pulmonary disease.

... Background Atypical manifestations of COVID-19 are being encountered as the pandemic unfolds, leading to non-chest CT scans that may uncover unsuspected pulmonary disease. Purpose To investigate patients with primary non-respiratory symptoms who underwent abdomen/pelvis or cervical spine/neck CT with ...

Ref: CT Scans Obtained for Nonpulmonary Indications: Associated Respiratory Findings of COVID-19 [Radiology, 2020]


The infected patients presented with fever, respiratory symptoms, sometimes with digestive and other systemic manifestations,

... was first reported in Wuhan, China and rapidly spread in other countries in December 2019. The infected patients presented with fever, respiratory symptoms, sometimes with digestive and other systemic manifestations, and some progressed with a severe acute respiratory syndrome or even death. Associated digestive symptoms ...

Ref: Specific ACE2 expression in small intestinal enterocytes may cause gastrointestinal symptoms and injury after 2019-nCoV infection [Int J Infect Dis, 2020]


Many patients with COVID-19 in Hunan region showed significant symptoms of diarrhea.

... Many patients with COVID-19 in Hunan region showed significant symptoms of diarrhea. By testing nucleic acid levels in stool of these patients, we found that the virus was present in both the respiratory tract and the stool of eight patients. Of these ...

Ref: The implications of preliminary screening and diagnosis: Clinical characteristics of 33 mild patients with SARS-CoV-2 infection in Hunan, China [J Clin Virol, 2020-04-30]


74 (11.4%) patients presented with at least one GI tract symptom (nausea, vomiting and diarrhoea),

... confirmed COVID-19 from 17 January 2020 to 8 February 2020 in Zhejiang province, among which 74 (11.4%) patients presented with at least one GI tract symptom (nausea, vomiting and diarrhoea), which was higher than previous Wuhan data (table 1) . In detail, of 74 patients ...

Ref: Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms [Gut, 2020-03-24]


mild temperature, cough, fatigue, nausea, vomiting, dry mucus membrane or hyperemic, dyspnea, consolidated pneumonia like lungs,

... by early detection and intervention. Course of Covid-19 followed concomitance to early symptoms appearance of mild temperature, cough, fatigue, nausea, vomiting, dry mucus membrane or hyperemic, dyspnea, consolidated pneumonia like lungs, accompanied with decline in blood oxygen saturation, leukopenia, lymphocytopenia, thrombocytopenia, elevation in Aspartate aminotransferase (AST), ...

Ref: EARLY DETECTION OF COVID-19 [Gut, 2020-04-07]


Mainly initial symptoms were cough and low fever (37.3–38.0 °C).

... Of ten patients, secondary, tertiary and quartus patients emerged; the incubation period was 3–7 days. Mainly initial symptoms were cough and low fever (37.3–38.0 °C). An asymptomatic case presented normal radiography, the others had ground glass opacities. All cases (three ...

Ref: Patients of COVID-19 may benefit from sustained Lopinavir-combined regimen and the increase of Eosinophil may predict the outcome of COVID-19 progression [Int J Infect Dis, 2020-03-12]


One hundred three patients (50.5%) admitted to the hospital were found to present with one or more digestive symptoms.

... and medical treatment of COVID-19 patients with digestive symptoms are shown in Table 1 . One hundred three patients (50.5%) admitted to the hospital were found to present with one or more digestive symptoms. Of these 103 patients, 97 had developed respiratory symptoms along with digestive symptoms and 6 ...

Ref: Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study [Am J Gastroenterol, 2020-04-14]


Fever was defined as a temperature higher than 37.5ºC.

... Fever was defined as a temperature higher than 37.5ºC. Lymphocytopenia was defined as a lymphocyte count of less than 1500 cells per cubic millimeter (mm 3 ). Thrombocytopenia was defined as a platelet count of less than 150.000/ mm ...

Ref: Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury [Am J Gastroenterol, 2020-04-24]


fever, cough, fatigue, and dyspnea [6, 8, 43] .

... The symptoms of COVID-19 are similar to other viral upper respiratory illnesses and include fever, cough, fatigue, and dyspnea [6, 8, 43] . The differential diagnosis for COVID-19 should be tailored to the patient and their presenting symptoms and ...

Ref: Coronavirus Disease (COVID-19): A primer for emergency physicians [Am J Emerg Med, 2020-03-24]


The presenting symptoms are mainly respiratory symptom, yet studies have reported nervous system involvement in the disease.

... disease 2019 (COVID-19) is a newly emerging infectious disease that has caused a global pandemic. The presenting symptoms are mainly respiratory symptom, yet studies have reported nervous system involvement in the disease. A systematic review and meta-analysis of these studies are required to understanding the neurologic characteristic ...

Ref: Neurologic Characteristics in Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis [Front Neurol, 2020-05-29]


The presenting symptoms are mainly respiratory symptom,

... disease 2019 (COVID-19) is a newly emerging infectious disease that has caused a global pandemic. The presenting symptoms are mainly respiratory symptom, yet studies have reported nervous system involvement in the disease. A systematic review and meta-analysis ...

Ref: Neurologic Characteristics in Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis [Front Neurol, 2020-05-29]


fever and cough are most commonly seen.

... The clinical symptoms of pediatric patients are non-specific. In the initial stage, fever and cough are most commonly seen. Besides, other symptoms might appear to be nasal congestion, runny nose, sore throat, fatigue, headache, myalgia, vomiting, and ...

Ref: CT features of novel coronavirus pneumonia (COVID-19) in children [Eur Radiol, 2020-04-14]


weakness and elevated creatinine kinase (CK).

... are herein to report two cases of SARS-CoV-2 induced rhabdomyolysis with an initial presentation of weakness and elevated creatinine kinase (CK). Both patients had no respiratory symptoms, they only complained of generalized weakness and were found ...

Ref: Weakness and elevated creatinine kinase as the initial presentation of coronavirus disease 2019 (COVID-19) [Am J Emerg Med, 2020-05-11]


fever, cough, dyspnea, myalgia, and fatigue (3) .

... evident that most cases of COVID-19 disease develop mild respiratory and constitutional symptoms such as fever, cough, dyspnea, myalgia, and fatigue (3) . A considerable number of COVID-19 infected cases are asymptomatic but they can transmit the disease ...

Ref: COVID-19 Pneumonia in Asymptomatic Trauma Patients; Report of 8 Cases [Arch Acad Emerg Med, 2020-04-06]


Nasal congestion, myalgia, headache, chills, fever, fatigue, and coughing

... author/funder, who has granted medRxiv a license to display the preprint in perpetuity. Nasal congestion, myalgia, headache, chills, fever, fatigue, and coughing were common initial symptoms, whereas gastrointestinal tract symptoms were rare initial symptoms. In this study, 5 (2.4%) ...

Ref: Gastrointestinal tract symptoms in coronavirus disease 2019: Analysis of clinical symptoms in adult patients [Arch Acad Emerg Med, 2020-03-27]


At the onset of Covid-19 infection, fever and asthenia were the most frequently observed symptoms,

... in a cohort of hospitalized patients who were already receiving close attention for their SCI. At the onset of Covid-19 infection, fever and asthenia were the most frequently observed symptoms, which slightly differed from other published series that identified cough and fever as initial symptoms ...

Ref: Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury [Spinal Cord Ser Cases, 2020-05-13]


In the initial stage, fever and cough are most commonly seen.

... The clinical symptoms of pediatric patients are non-specific. In the initial stage, fever and cough are most commonly seen. Besides, other symptoms might appear to be nasal congestion, runny nose, sore throat, fatigue, headache, myalgia, vomiting, and diarrhea [11, 19, 20] ...

Ref: CT features of novel coronavirus pneumonia (COVID-19) in children [Eur Radiol, 2020-04-14]


early identification of severe illness is critical for controlling it and improving the prognosis of patients with limited medical resources.

... COVID‐19 has developed into a worldwide pandemic; early identification of severe illness is critical for controlling it and improving the prognosis of patients with limited medical resources. The present study aimed to analyze the characteristics of severe COVID‐19 and identify biomarkers for differential diagnosis and prognosis prediction. In total, 27 ...

Ref: C‐reactive protein correlates with computed tomographic findings and predicts severe COVID‐19 early [J Med Virol, 2020-04-25]


fever + cough) in 1351 (91%) cases and according to PCR test in 197 (13%) cases.

... median age of 44 (32-57) years. Among these patients, 28 (2%) were aged under 16 years and 12 (1%) under 10. COVID-19 infection was diagnosed according to clinical symptoms ( fever + cough) in 1351 (91%) cases and according to PCR test in 197 (13%) cases. ...

Ref: Clinical features of 1487 COVID-19 patients with outpatient management in the Greater Paris: the COVID-call study [Intern Emerg Med, 2020-05-30]


some patients are presenting with abdominal symptoms without respiratory complaints.

... As the 2019 novel coronavirus disease (COVID-19) continues to spread, some patients are presenting with abdominal symptoms without respiratory complaints. Our case series documents four patients who presented with abdominal symptoms whose abdominopelvic CT revealed incidental pulmonary parenchymal findings in ...

Ref: Incidental CT findings in the lungs in COVID-19 patients presenting with abdominal pain [Clin Imaging, 2020-05-28]


One asymptomatic primary case suffered from difficulty breathing, shortness of breath, and chest tightness in the 17 days during treatment.

... The two asymptomatic primary cases had neither symptoms nor chest CT findings during the treatment. One asymptomatic primary case suffered from difficulty breathing, shortness of breath, and chest tightness in the 17 days during treatment. Most importantly, all of their family contacts developed symptoms before the admission date of the ...

Ref: Epidemiological and Clinical Characteristics of COVID-19 in Adolescents and Young Adults [The Innovation, 2020-05-21]


• Severe manifestation on CT at an early stage may indicate poor prognosis for older patients with COVID-19.

... at an early stage may indicate poor prognosis for older patients with COVID-19. KEY POINTS: • Severe manifestation on CT at an early stage may indicate poor prognosis for older patients with COVID-19. • Radiologists should pay attention to the time interval between symptom onsets and CT scans ...

Ref: Association of "initial CT" findings with mortality in older patients with coronavirus disease 2019 (COVID-19) [Eur. radiol, 2020]


The clinical features include fever, dry cough, dyspnea, myalgia, fatigue, decreased leukocyte counts and computed tomography (CT) evidence of pneumonia.

... linked to the Wuhan Huanan Seafood Wholesale Market, as reported by Huang and colleagues. 8 The clinical features include fever, dry cough, dyspnea, myalgia, fatigue, decreased leukocyte counts and computed tomography (CT) evidence of pneumonia. 8 Subsequently, Chen and colleagues reported 99 cases from a single centre of Wuhan, but ...

Ref: Epidemiologic and Clinical Characteristics of 91 Hospitalized Patients with COVID-19 in Zhejiang, China: A retrospective, multi-centre case series [QJM, 2020-03-17]


The main clinical manifestations of COVID-19 pneumonia are acute respiratory symptoms.

... in children. In this study, there was only 1 case in an adolescent, aged 17. The main clinical manifestations of COVID-19 pneumonia are acute respiratory symptoms. Fever, dry cough, and fatigue are common symptoms of COVID-19 pneumonia. In severe cases, dyspnea ...

Ref: Imaging characteristics of initial chest computed tomography and clinical manifestations of patients with COVID-19 pneumonia [Jpn J Radiol, 2020-04-21]


patients with COVID-19 exhibited milder or more moderate symptoms and a lower proportion of liver dysfunction compared with patients in Wuhan.

... in Hubei. An early study including 80 cases of COVID-19 in Jiangsu province showed that patients with COVID-19 exhibited milder or more moderate symptoms and a lower proportion of liver dysfunction compared with patients in Wuhan. 38 Our subgroup analysis suggested that no difference existed in the rate of overall gastrointestinal ...

Ref: Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis [Lancet Gastroenterol Hepatol, 2020-05-12]


can invade the human body by binding to the human angiotensin converting enzyme 2 (ACE-2) receptor,

... reasons why COVID-19 seems to cause digestive symptoms. First, SARS-CoV-2 is similar to SARS-CoV and can invade the human body by binding to the human angiotensin converting enzyme 2 (ACE-2) receptor, which causes liver tissue injury by the upregulation of ACE-2 expression in liver tissue caused ...

Ref: Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study [Am J Gastroenterol, 2020-04-14]


anecdotally reported loss of smell and taste.

... early or subclinical symptoms of coronavirus disease 2019 (COVID-19) infection. Two such candidate symptoms include anecdotally reported loss of smell and taste. Understanding the timing and association of smell/taste loss in COVID-19 may help facilitate screening and ...

Ref: Association of chemosensory dysfunction and COVID-19 in patients presenting with influenza-like symptoms [Int. forum allergy rhinol, 2020]


evidence of progressive lung involvement on chest imaging studies.

... underlines the appearance of a “walking pneumonia” in a novel coronavirus disease (COVID-19) patient, with evidence of progressive lung involvement on chest imaging studies. The patient traveled from Wuhan, Hubei, China, to Thailand in January 2020. One of her ...

Ref: Case Report: Walking Pneumonia in Novel Coronavirus Disease (COVID-19): Mild Symptoms with Marked Abnormalities on Chest Imaging [Am J Trop Med Hyg, 2020-04-01]


The patient developed fever and respiratory symptoms at disease onset, followed by muscle soreness, and subsequently altered consciousness and psychiatric symptoms,

... a rare case of a patient diagnosed with COVID‐19 who manifested with concomitant neurological symptoms. The patient developed fever and respiratory symptoms at disease onset, followed by muscle soreness, and subsequently altered consciousness and psychiatric symptoms, with positive signs based on neurological examination. The patient tested positive for the severe acute ...

Ref: Concomitant neurological symptoms observed in a patient diagnosed with coronavirus disease 2019 [J Med Virol, 2020-04-15]


cough, 65 fever, myalgia, dyspnea, headache and loss of appetite.

... the same reviewers. 63 3. Clinical presentation 64 The common symptoms in COVID-19 patients were cough, 65 fever, myalgia, dyspnea, headache and loss of appetite. The 66 most common ENT symptoms were facial pain and nasal con-67 gestion [9] . ...

Ref: The diagnostic value of detecting sudden smell loss among asymptomatic COVID-19 patients in early stage: The possible early sign of COVID-19 [Auris Nasus Larynx, 2020-06-09]


fever, a dry cough, shortness of breath, myalgia or fatigue, and dyspnea

... common signs and symptoms of the 2019 novel coronavirus (COVID-19; temporarily termed as 2019-nCoV) at onset are fever, a dry cough, shortness of breath, myalgia or fatigue, and dyspnea . Owing to the complexity of COVID-19, some patients may present with atypical ...

Ref: 2019 Novel Coronavirus (COVID-19) Pneumonia with Hemoptysis as the Initial Symptom: CT and Clinical Features [Korean J Radiol, 2020-03-13]


Of 535 patients, 27 patients (5.0%) presented with conjunctival congestion and 4 patients had conjunctival congestion as the initial symptom.

... in nasopharyngeal swabs by real-time PCR was collected from questionnaires and electronic medical records. RESULTS: Of 535 patients, 27 patients (5.0%) presented with conjunctival congestion and 4 patients had conjunctival congestion as the initial symptom. The average duration of conjunctival congestion was 5.9 ± 4.5 days (mean [SD]). The other ...

Ref: Ocular manifestations and clinical characteristics of 535 cases of COVID-19 in Wuhan, China: a cross-sectional study [Acta Ophthalmol, 2020]


an initial (often infectious or inflammatory) acute insult causes ground-glass opacities that may coalesce into dense consolidative lesions,

... with the blueprint thoracic radiologists recognize as the archetypal response to acute lung injury whereby an initial (often infectious or inflammatory) acute insult causes ground-glass opacities that may coalesce into dense consolidative lesions, and then progressively evolve and organize in often a more linear fashion with predilection for ...

Ref: Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection [Radiology, 2020-02-20]


The most common onset symptoms were fever and dry cough,

... COVID-19 cases (29/34, p < 0.05) had direct contact with COVID-19 patients or Wuhan city. The most common onset symptoms were fever and dry cough, and there were no significant differences in patient symptoms between the two groups. The incidence ...

Ref: Diagnostic performance between CT and initial real-time RT-PCR for clinically suspected 2019 coronavirus disease (COVID-19) patients outside Wuhan, China [Respir Med, 2020-04-21]


The symptoms are undiagnostic, the results of viral nucleic acid detection method (PCR) can delay,

... COVID-19 pneumonia has high mortality rates. The symptoms are undiagnostic, the results of viral nucleic acid detection method (PCR) can delay, so that chest computerized tomography is often key diagnostic test in patients with possible COVID-19 pneumonia. In this review, we discussed the main radiological ...

Ref: Radiological approaches to COVID-19 pneumonia [Turk J Med Sci, 2020-04-21]


three patients with mild clinical symptoms only showed pharyngeal discomfort

... CT findings of some patients may not be consistent with their clinical symptoms. For example, three patients with mild clinical symptoms only showed pharyngeal discomfort but because one of their family members had been diagnosed with COVID-19 pneumonia, they underwent ...

Ref: Chest computed tomography findings of coronavirus disease 2019 (COVID-19) pneumonia [Eur Radiol, 2020-05-20]


fever, cough and headache.

... admission. The symptomtic group was defined as those patients with any clinical symptoms such as fever, cough and headache. According to the diagnostic and treatment guidelines for COVID-19 issued by the Chinese National Health ...

Ref: Clinical features of imported cases of coronavirus disease 2019 in Tibetan patients in the Plateau area [Eur Radiol, 2020-03-13]


fever, dry cough, dyspnea), and 32 of the 247 (20%) had characteristic CT scan images of COVID-19 pneumonia.

... symptoms also had COVID-19 respiratory symptoms (defined as at least 2 of the following : fever, dry cough, dyspnea), and 32 of the 247 (20%) had characteristic CT scan images of COVID-19 pneumonia. The majority of patients in both subgroups were lymphopenic : 91 (33.5%) had deep lymphopenia<700/µL ...

Ref: High mortality rate in cancer patients with symptoms of COVID-19 with or without detectable SARS-COV-2 on RT-PCR [Eur J Cancer, 2020-06-07]


The most common clinical manifestations of the disease are fever, cough, and dyspnea.

... human-to-human transmission of SARS-CoV2, even by asymptomatic carriers has led to an intensive health disaster. The most common clinical manifestations of the disease are fever, cough, and dyspnea. Some complications such as ARDS, acute kidney injury, and liver damage may also occur during ...

Ref: The outlook for diagnostic purposes of the 2019‐novel coronavirus disease [J Cell Physiol, 2020-05-26]


The body temperature of non-hospitalized patients with mild symptoms returned to normal by day 4-5.

... time of diagnosis. 33.3% inpatients exhibited negative changes in their CT results at initial diagnosis. The body temperature of non-hospitalized patients with mild symptoms returned to normal by day 4-5. While dyspnea peaked on day 6 for non-hospitalized patients with mild symptoms, it persisted in ...

Ref: Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 during home care with isolation: A new retrospective analysis based on O2O [J Cell Physiol, 2020-02-29]


The initial symptoms of the nine children were mild,

... was confirmed to have 2019‐nCoV infection, among whom the median incubation period was 7.5 days. The initial symptoms of the nine children were mild, including fever (3/9), diarrhea (2/9), cough (1/9), and sore throat (1/9), two had no symptoms. ...

Ref: Novel coronavirus infection in children outside of Wuhan, China [Pediatr Pulmonol, 2020-04-07]


physicians should pay close attention to any neurologic manifestations in addition to the symptoms of respiratory system.

... Their clinical conditions may worsen and patients may die soon. Therefore, for patient with COVID19, physicians should pay close attention to any neurologic manifestations in addition to the symptoms of respiratory system. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. ...

Ref: Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study [Pediatr Pulmonol, 2020-02-25]


The first symptom of COVID-19 patient A was sore throat,

... The first symptom of COVID-19 patient A was sore throat, which developed on the day (28th January, illness day 1; Fig. 1A ) next to his contact with Taiwan No. 19 case patient. Productive cough and rhinorrhea appeared on illness ...

Ref: Featuring COVID-19 cases via screening symptomatic patients with epidemiologic link during flu season in a medical center of central Taiwan [J Microbiol Immunol Infect, 2020-03-13]


fever being the most common is the main reason for visiting the ED.

... Having initial clinical symptoms, fever being the most common is the main reason for visiting the ED. 15 In our study, fever and cough were the most common symptoms observed in all patients with suspected disease. Due to the high seasonal incidence of ...

Ref: Initial clinical features of suspected coronavirus disease 2019 in two emergency departments outside of Hubei, China [J Med Virol, 2020-03-24]


fever, sore throat and so on, within 14 days of exposure or a contact history with suspected or confirmed cases.

... should ask patients and their companions whether they have typical symptoms of COVID-19, such as fever, sore throat and so on, within 14 days of exposure or a contact history with suspected or confirmed cases. Patients should have a chest CT at the same time of having a head CT. ...

Ref: Consensus for prevention and management of coronavirus disease 2019 (COVID-19) for neurologists [Stroke Vasc Neurol, 2020-04-01]


fever, tiredness and dry cough.

... of Coronavirus Disease 2019 (COVID-19) is based on the identification of common symptoms such as fever, tiredness and dry cough. Anosmia and ageusia are also in fact symptoms of the infection with the new coronavirus ...

Ref: Anosmia: A marker of infection by the new corona virus [Respir Med Case Rep, 2020-06-12]


Patients 9, 19 and 25 were asymptomatic, but CT showed intrapulmonary lesions.

... Patients 9, 19 and 25 were asymptomatic, but CT showed intrapulmonary lesions. Small thin and patchy GGO could be seen on the chest CT in patient 21 (Fig. 5) , and the PCR results were negative twice. Later, the third PCR result ...

Ref: A retrospective study of the initial 25 COVID-19 patients in Luoyang, China [Jpn J Radiol, 2020-05-26]


The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity.

... after symptom onset. Viral shedding was high from day 1 of illness, especially from the upper respiratory tract (URT). CONCLUSION: The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity. Viral shedding from URT was high from the prodromal phase. ...

Ref: Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19 [J Korean Med Sci, 2020]


Patients developed their symptoms (fever, cough, dyspnea, and fatigue) 1, 2, 4, and 14 days after surgery.

... age and body mass index were 46 ± 12 years and 49 ± 3 kg/m(2). Patients developed their symptoms (fever, cough, dyspnea, and fatigue) 1, 2, 4, and 14 days after surgery. One patient had unnoticed anosmia 2 days before surgery. Three patients were readmitted in hospital. ...

Ref: Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak [Obes Surg, 2020-04-20]


Fever, cough, and dyspnea were the most common clinical symptoms,

... evaluated for symptoms, laboratory data, imaging findings, and outcomes from February 2020 to April 2020. Fever, cough, and dyspnea were the most common clinical symptoms, noted in 75% (nine/12), 75% (nine/12), and 41.7% (five/12) of the patients, respectively. Most of ...

Ref: Clinical Course, Imaging Features, and Outcomes of COVID-19 in Kidney Transplant Recipients [Eur Urol, 2020-05-06]


99 (48.5%) presented with digestive symptoms as their chief complaint.

... Hubei, China. Among the 204 patients with COVID-19 and full laboratory, imaging, and historical data, 99 (48.5%) presented with digestive symptoms as their chief complaint. Patients with digestive symptoms had a variety of manifestations, including anorexia (83.8%), vomiting (0.8%), diarrhea ...

Ref: Gastrointestinal and liver manifestations in patients with COVID-19 [J Chin Med Assoc, 2020-04-21]


fever, cough, dyspnoea and malaise.

... likely to establish, COVID-19 suspicion should be based on the most common presenting signs of fever, cough, dyspnoea and malaise. It is of crucial importance to understand that the current sensitivity of SARS-CoV-2 molecular tests ...

Ref: Does this patient have COVID-19? A practical guide for the internist [Intern Emerg Med, 2020-05-23]


The common clinical manifestations were fever, cough, and fatigue.

... of patients was 41 years, and the median length of hospital stay was 9 days. The common clinical manifestations were fever, cough, and fatigue. A few patients had pharyngeal pain and muscle pain. These cases usually have a long ...

Ref: cord_uid mq9vjnro Clinical characteristics and drug therapies in... mq9vjnro Clinical characteristics and drug therapies in... Name: title, dtype: object [Intern Emerg Med, cord_uid mq9vjnro 2020-05-14 mq9vjnro 2020-05-14 Name: publish_time, dtype: object]


irritative symptoms of the lower urinary tract and high urinary frequency.

... as endotheliitis [4] , are a hallmark in COVID-19 patients leading to symptoms such as irritative symptoms of the lower urinary tract and high urinary frequency. Interestingly, three patients presented with microhematuria, which possibly further supports the hypothesis of SARS-CoV-2induced viral ...

Ref: Urinary Frequency as a Possibly Overlooked Symptom in COVID-19 Patients: Does SARS-CoV-2 Cause Viral Cystitis? [Eur Urol, 2020-05-19]


Illness ranged from mild to moderately severe, and hospitalized patients showed signs of clinical worsening in the second week.

... contact with a patient with confirmed COVID-19 in the United States, representing domestic human-to-human transmission. Illness ranged from mild to moderately severe, and hospitalized patients showed signs of clinical worsening in the second week. All patients recovered or are improving, and three patients tolerated treatment with the investigational antiviral ...

Ref: First 12 patients with coronavirus disease 2019 (COVID-19) in the United States [Eur Urol, 2020-03-12]


Fever and cough were the main symptoms in patients with COVID-19,

... The diagnosis of suspected cases in children needs comprehensive consideration. Fever and cough were the main symptoms in patients with COVID-19, which is reported by the most of current guidelines and recommendations. (12, 90-93) Although fever and cough All rights reserved. ...

Ref: Clinical Characteristics of Children with COVID-19: A Rapid Review and Meta-Analysis [Eur Urol, 2020-04-17]


fever, fatigue, dry cough, nasal congestion, runny nose, sore throat, and diarrhea.

... hosted by John Hopkins University. 4 Common clinical symptoms of patients infected with COVID-19, include fever, fatigue, dry cough, nasal congestion, runny nose, sore throat, and diarrhea. In severe cases, patients present with dyspnea and/ or hypoxemia 1 week after the onset ...

Ref: Chest Imaging in Patients Hospitalized With COVID-19 Infection - A Case Series [Curr Probl Diagn Radiol, 2020-04-11]


fever, cough, and myalgia and fatigue [1] [2] [3] .

... Common presenting symptoms for patients with confirmed infection include fever, cough, and myalgia and fatigue [1] [2] [3] . Typical laboratory findings on admission include normal leucocytes in majority of patients and decreased lymphocytes in 35% of patients [2] . ...

Ref: Evolution of CT findings in patients with mild COVID-19 pneumonia [Eur Radiol, 2020-04-15]


walking pneumonia” in a novel coronavirus disease (COVID-19) patient, with evidence of progressive lung involvement on chest imaging studies.

... This case report underlines the appearance of a “ walking pneumonia” in a novel coronavirus disease (COVID-19) patient, with evidence of progressive lung involvement on chest imaging studies. The patient traveled from Wuhan, Hubei, China, to Thailand in January 2020. One of her family members was diagnosed with COVID-19. ...

Ref: Case Report: Walking Pneumonia in Novel Coronavirus Disease (COVID-19): Mild Symptoms with Marked Abnormalities on Chest Imaging [Am J Trop Med Hyg, 2020-04-01]