¿En que se diferencia el coronavirus de la gripe?

(How does the coronavirus differ from seasonal flu?)

Primeras 5 respuestas:

Dental professionals are at an increased risk for contracting these viruses from dental patients,

Seasonal influenza (flu) is an underappreciated source of disease morbidity and mortality worldwide.

Pollen are documented to invoke strong immune responses and might create an environmental factor that makes it more difficult for flu-like viruses to survive outside a host.

Meteorological factors alone do not predict seasonality, given substantial climate differences between countries that are subject to flu-like epidemics or COVID-19.

seasonal respiratory pathogens are more prevalent than SARS-CoV-2 in symptomatic patients in non- COVID-19 endemic area during the flu season.

Dental professionals are at an increased risk for contracting these viruses from dental patients,

... Spanish flu (H1N1), severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and others. Dental professionals are at an increased risk for contracting these viruses from dental patients, as dental practice involves face-to-face communication with the patients and frequent exposure to saliva, blood, ...

Ref: Are dental schools adequately preparing dental students to face outbreaks of infectious diseases such as COVID-19? [J Dent Educ, 2020]

Seasonal influenza (flu) is an underappreciated source of disease morbidity and mortality worldwide.

... Seasonal influenza (flu) is an underappreciated source of disease morbidity and mortality worldwide. While vaccination remains the cornerstone of influenza prevention, common measures practiced during the COVID-19 pandemic such as social distancing, the use of protective face masks, and frequent hand washing are ...

Ref: Social Distancing and Personal Protective Measures Decrease Influenza Morbidity and Mortality [J Dent Educ, 2020-04-22]

Pollen are documented to invoke strong immune responses and might create an environmental factor that makes it more difficult for flu-like viruses to survive outside a host.

... countries with moderate climates. It is hypothesized that one major factor is overlooked: pollen count. Pollen are documented to invoke strong immune responses and might create an environmental factor that makes it more difficult for flu-like viruses to survive outside a host. This Dutch study confirms that there is a (highly) significant inverse correlation between pollen count ...

Ref: Pollen likely seasonal factor in inhibiting flu-like epidemics. A Dutch study into the inverse relation between pollen counts, hay fever and flu-like incidence 2016-2019 [Sci Total Environ, 2020]

Meteorological factors alone do not predict seasonality, given substantial climate differences between countries that are subject to flu-like epidemics or COVID-19.

... Current models for flu-like epidemics insufficiently explain multi-cycle seasonality. Meteorological factors alone do not predict seasonality, given substantial climate differences between countries that are subject to flu-like epidemics or COVID-19. Pollen is documented to be antiviral and allergenic, play a role in immuno-activation, and seems to create a bio-aerosol lowering the ...

Ref: Pollen Explains Flu-Like and COVID-19 Seasonality [Sci Total Environ, 2020-06-07]

seasonal respiratory pathogens are more prevalent than SARS-CoV-2 in symptomatic patients in non- COVID-19 endemic area during the flu season.

... Panel revealed 22 of the 41 non-COVID-19 patients were infected by particular pathogens. In general, seasonal respiratory pathogens are more prevalent than SARS-CoV-2 in symptomatic patients in non- COVID-19 endemic area during the flu season. Since all patients shared similar clinical and laboratory findings, expanded surveillance of detailed exposure history ...

Ref: Featuring COVID-19 cases via screening symptomatic patients with epidemiologic link during flu season in a medical center of central Taiwan [J Microbiol Immunol Infect, 2020]

SARS-CoV-2 causes a generally mild, but sometimes severe and even life-threatening infection, known as COVID-19.

... The emerging coronavirus SARS-CoV-2 has caused a COVID-19 pandemic. SARS-CoV-2 causes a generally mild, but sometimes severe and even life-threatening infection, known as COVID-19. Currently, there exist no effective vaccines or drugs and, as such, global public authorities have so far relied upon non pharmaceutical ...

Ref: Modeling the impact of mass influenza vaccination and public health interventions on COVID-19 epidemics with limited detection capability [Math Biosci, 2020]

There are many similarities between the COVID 19 epidemic and the Spanish flu epidemic.

... pandemic and hit all the Countries, all over the world, from the beginning of the year 2020. There are many similarities between the COVID 19 epidemic and the Spanish flu epidemic. We considered some preventive measures which do not change in the two epidemics. ...

Ref: COVID 19 and Spanish flu pandemics: All it changes, nothing changes [Acta Biomed, 2020]

HCoV-229E was the most common species, appearing in most months and without an obvious seasonal distribution.

... The seasonal distribution of HCoVs is shown in Fig.1 . HCoV-229E was the most common species, appearing in most months and without an obvious seasonal distribution. Peaks in 229E detections occurred in May 2009, December 2009 and August 2010, corresponding with spring, winter and summer, respectively, ...

Ref: Characterization of Human Coronavirus Etiology in Chinese Adults with Acute Upper Respiratory Tract Infection by Real-Time RT-PCR Assays [PLoS One, 2012-06-15]

There is uncertainty if current models for the Covid-19 pandemic should already take into account seasonality.

... There is uncertainty if current models for the Covid-19 pandemic should already take into account seasonality. That is because current environmental factors do not provide a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates. It is hypothesized that one major ...

Fever was the most common symptom in the respiratory virus infection patients.

Ref: Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing [Int J Infect Dis, 2020-05-07]

Whereas COVID-19 commonly presents as a flu-like illness with fever and persistent cough as its main symptoms,

... of seasonal allergic rhinitis (SAR) share a few similarities in their phenotype, but also differences. Whereas COVID-19 commonly presents as a flu-like illness with fever and persistent cough as its main symptoms, there is evidence of milder disease, especially in younger people. According to the WHO some ...

Ref: Allergic respiratory disease care in the COVID-19 era: a EUFOREA statement [World Allergy Organ J, 2020-05-16]

The novel coronavirus, since its first outbreak in December, has, up till now, affected approximately 114,542 people across 115 countries.

... The novel coronavirus, since its first outbreak in December, has, up till now, affected approximately 114,542 people across 115 countries. Many international agencies are devoting efforts to enhance the understanding of the evolving COVID-19 outbreak on an international level, its influences, and preparedness. At present, COVID-19 appears to affect individuals ...

Ref: On the global trends and spread of the COVID-19 outbreak: preliminary assessment of the potential relation between location-specific temperature and UV index [Z Gesundh Wiss, 2020]

No cases of severe seasonal flu and no deaths by seasonal flu were observed.

... The two independent drivers of the risk were clinically active IBD and exposure to thiopurines. No cases of severe seasonal flu and no deaths by seasonal flu were observed. Although many of our patients have been vaccinated against seasonal flu, as recommended by European ...

Ref: Management of IBD during the COVID-19 outbreak: resetting clinical priorities [Nat Rev Gastroenterol Hepatol, 2020-03-25]

can manifest with flu-like illness and severe pneumonia with acute respiratory distress syndrome (ARDS).

... Coronavirus disease 2019 (COVID-19), mediated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can manifest with flu-like illness and severe pneumonia with acute respiratory distress syndrome (ARDS). Immunocompromised patients merit particular attention as altered host immunity may influence both disease severity and duration of ...

Ref: Coronavirus Disease 2019 in an Orthotopic Liver Transplant Recipient Living with Human Immunodeficiency Virus. [Transplant infectious disease : an official journal of the Transplantation Society, 2020-06-05]

Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments.

... a novel betacoronavirus, known as severe acute respiratory syndrome coronavirus 2, progressively spread in Italy. Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments. From the first Italian government restrictions (23rd February), Modena Cancer Center adopted practical health vigilance ...

Ref: Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! [Eur J Cancer, 2020]

This is important when considering the additional faecal shedding of this virus [7] .

... of an undoubtedly lower epidemiological role, this capacity indicates a significant difference from flu viruses. This is important when considering the additional faecal shedding of this virus [7] . Although the impact of climate characteristics typical of the end of spring and summer, e.g. ...

Ref: COVID-19 and globalization [One Health, 2020-04-10]

It is hypothesized that one major factor is overlooked: pollen count.

... a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates. It is hypothesized that one major factor is overlooked: pollen count. Pollen are documented to invoke strong immune responses and might create an environmental factor that ...

Ref: Pollen likely seasonal factor in inhibiting flu-like epidemics. A Dutch study into the inverse relation between pollen counts, hay fever and flu-like incidence 2016–2019 [Sci Total Environ, 2020-07-20]

The higher prevalence of LV failure and lower cardiac index in patients with flu-related ARDS is presumably related to septic cardiomyopathy

... The higher prevalence of LV failure and lower cardiac index in patients with flu-related ARDS is presumably related to septic cardiomyopathy since they sustained associated septic shock more frequently than COVID-19 patients. Depressed indices of RV systolic function and elevated central venous pressure reflecting systemic venous congestion reflect the higher prevalence ...

Ref: Cardiovascular phenotypes in ventilated patients with COVID-19 acute respiratory distress syndrome [Crit Care, 2020-05-18]

Rhinoviruses, adenoviruses, and RSV were found to be the most common pathogens in pediatric patients.

... patterns and seasonal distribution of human respiratory pathogens in the central region of Saudi Arabia. Rhinoviruses, adenoviruses, and RSV were found to be the most common pathogens in pediatric patients. The RV16 based PCR diagnostic approach increased our understanding of viral etiology for better management, ...

Ref: Respiratory Tract Viral Infections and Coinfections Identified by Anyplex™ II RV16 Detection Kit in Pediatric Patients at a Riyadh Tertiary Care Hospital [Biomed Res Int, 2017-11-21]

Flu-like symptoms with dyspnea may distinguish COVID-19 infection from dyspnea due to a COPD-related exacerbation.

... Patients with COPD have an increased risk for severity of COVID-19. Flu-like symptoms with dyspnea may distinguish COVID-19 infection from dyspnea due to a COPD-related exacerbation. Management of COPD with COVID-19 warrants standard-of-care treatment with antimicrobial agents and corticosteroids, though limiting the dose and duration ...

Ref: Management of patients with COPD during the COVID-19 pandemic [Clevel. clin. j. med, 2020]

Acute respiratory infections are one of the top five causes of mortality worldwide and contribute to >4 million deaths per year.

... Acute respiratory infections are one of the top five causes of mortality worldwide and contribute to >4 million deaths per year. Consequently, emerging respiratory viruses are a continuing threat to global health security and have the potential to affect our economies. Since the millennium, there have been around a dozen different ...

Ref: Influenza and other emerging respiratory viruses [Medicine (Abingdon), 2017-10-27]

The coronavirus disease pandemic has revealed many failures in different countries and systems that have combined to yield lethal consequences.

... George Santayana wrote "Those who cannot remember the past are condemned to repeat it." The coronavirus disease pandemic has revealed many failures in different countries and systems that have combined to yield lethal consequences. Such failures, as well as actions in ongoing responses, contain elements that many members of the ...

Ref: Coronavirus and Risk Analysis [Risk Anal, 2020-04-08]

PIC infections were more Fig. 1 Detection frequencies of respiratory viruses in Beijing and Shanghai according to matched age groups.

... . In this study, the seasonal distribution of viral infections differed in Beijing and Shanghai. PIC infections were more Fig. 1 Detection frequencies of respiratory viruses in Beijing and Shanghai according to matched age groups. We considered P < 0.05 to be significant (marked as an asterisk) for all analyses ...

Ref: Comparison of viral and epidemiological profiles of hospitalized children with severe acute respiratory infection in Beijing and Shanghai, China [BMC Infect Dis, 2019-08-20]

The clinical symptoms of COVID-19 are very similar to other respiratory viruses.

... Wuhan, China, have been spread to more than 210 countries around the globe including India. The clinical symptoms of COVID-19 are very similar to other respiratory viruses. The number of laboratory-confirmed cases and associated deaths are increasing regularly in various parts of ...

Ref: The Indian perspective of COVID-19 outbreak [Virusdisease, 2020]

The detection rate was 11.78% in this study, significantly higher than in previous reports [5] .

... human coronavirus (HCoV) [18] , with HCoV-229E and -OC43 being the most common [18] . The detection rate was 11.78% in this study, significantly higher than in previous reports [5] . All four non-SARS HCoVs (-OC43, -229E, -NL63, and -HKU1) were detected, the highest being HCoV-229E ...

Ref: Etiology and Clinical Characterization of Respiratory Virus Infections in Adult Patients Attending an Emergency Department in Beijing [PLoS One, 2012-02-28]

During March, the toll of new cases and deaths kept surging,

... by the end of February, the virus had spread over northern regions of the country. During March, the toll of new cases and deaths kept surging, rapidly overtaking the numbers registered in China and making Italy the hardest-hit country in Europe ...

Ref: Google trends and COVID-19 in Italy: could we brace for impact? [Intern Emerg Med, 2020-05-25]

Initial enthusiasm for the combination of hydroxychloroquine and azithromycin has abated.

... to urgent attempts to find effective therapeutic agents for inpatient and outpatient treatment of COVID-19. Initial enthusiasm for the combination of hydroxychloroquine and azithromycin has abated. However, as a result of positive clinical experience with azithromycin used alone during the first ...

Ref: Azithromycin and COVID-19Prompt Early Use at First Signs of this Infection in Adults and Children An Approach Worthy of Consideration. [Dermatologic therapy, 2020-06-08]

COVID-19 mortality burden is indeed an order of magnitude greater than that of seasonal influenza.

In conclusion, comparing actual influenza and COVID-19 deaths in the same city suggests that COVID-19 mortality burden is indeed an order of magnitude greater than that of seasonal influenza.

Ref: Relative disease burdens of COVID-19 and seasonal influenza in New York City, February 1 - April 18, 2020. [Dermatologic therapy, 2020-04-27]

SARS was found to be less contagious than H1N1 or EV, but with a significantly higher fatality rate.

... EpiRank to the 2003 SARS outbreak in north Taiwan for comparison with H1N1 and EV. SARS was found to be less contagious than H1N1 or EV, but with a significantly higher fatality rate. The characteristics of these diseases determined their specific spatial spreading patterns, as reflected in the ...

Ref: Using EpiRank for Analyzing Emerging Coronavirus Epidemic Patterns [Dermatologic therapy, 2020-04-24]

Although most of the patients present with less severe symptoms like rhinitis, cough, fever, and mild flu-like symptoms,

... coronavirus 2 (SARS-CoV-2) due to its similarities with the virus was caused SARS outbreak (SARS-CoV). Although most of the patients present with less severe symptoms like rhinitis, cough, fever, and mild flu-like symptoms, it may progress to severe acute respiratory illness, pneumonia or acute respiratory distress syndrome (ARDS) ...

Ref: Respiratory and ventilator management of COVID-19 [J Pak Med Assoc, 2020]

HCov-229E is one of the four flu-causing coronaviruses which share great sequence similitude,

... chloroquine),1 a safety issue is addressed, concerning the selection of patients suitable to receive it. HCov-229E is one of the four flu-causing coronaviruses which share great sequence similitude, while many symptoms of patients infected with COVID-19 resemble those of patients infected with these ...

Ref: G6PD and chloroquine: Selecting the treatment against SARS‐CoV‐2? [J Cell Mol Med, 2020-04-16]

Approximately 13% of participants experienced an ILI with coronavirus, rhinovirus, enterovirus, and influenza identified as the leading causes of symptomatic illness.

... combat training at Fort Benning with the goal of informing development of effective control strategies. Approximately 13% of participants experienced an ILI with coronavirus, rhinovirus, enterovirus, and influenza identified as the leading causes of symptomatic illness. 19 These same viruses also circulated widely among asymptomatic recruits. Analysis of transmission patterns, using ...

Ref: The Acute Respiratory Infection Consortium: A Multi-Site, Multi-Disciplinary Clinical Research Network in the Department of Defense [Mil Med, 2019-11-28]

COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics

... morbidity and mortality. A current pandemic is caused by novel corona virus originated from China. COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics in terms of spreading to world by the mobilized people. Burden of pandemic is considered ...

Ref: Understanding dynamics of pandemics [Turk J Med Sci, 2020]

Data on mortality from SARS-CoV-2 infection are contradictory;

... China are clearly declining, case numbers in many European regions are no longer increasing exponentially.- Data on mortality from SARS-CoV-2 infection are contradictory; mortality is certainly lower than for SARS and MERS, but probably higher than for most ...

Ref: [SARS-CoV-2 infection (COVID-19): what can we expect?] [Deutsche medizinische Wochenschrift, 2020-06-01]

The ratio of fever to the highest temperature was higher in Flu A virus infection patients than in COVID-19 patients.

... of clustering onset than other groups. Fever was the most common symptom in these patients. The ratio of fever to the highest temperature was higher in Flu A virus infection patients than in COVID-19 patients. COVID-19 patients had a lower white blood cell count and neutrophil count than Flu A ...

Ref: Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing [Int J Infect Dis, 2020]

The virus is new, rapidly spreading, with a mortality rate of about 2% at the time of writing this editorial,

... of the novel coronavirus, 2019-nCoV, has dominated headlines throughout the world. This is not surprising. The virus is new, rapidly spreading, with a mortality rate of about 2% at the time of writing this editorial, and there are many uncertainties concerning its origins, nature, and course. The number of 2019-nCoV ...

Ref: Coronaphobia: Fear and the 2019-nCoV outbreak [J Anxiety Disord, 2020-02-10]

It is more infectious and fatal than seasonal influenza, and definitive treatment and a vaccine are months away.

... is a novel virus so most of the world’s population does not have prior immunity to it. It is more infectious and fatal than seasonal influenza, and definitive treatment and a vaccine are months away. Our arsenal against it is currently mainly social distancing and infection control measures. ...

Ref: How Should the Rehabilitation Community Prepare for 2019-nCoV? [Arch Phys Med Rehabil, 2020-03-16]

This new Coronavirus seems to be very infectious and has spread quickly and globally.

... with other symptoms such as a cough, fever, and in more severe cases, difficulty breathing. This new Coronavirus seems to be very infectious and has spread quickly and globally. In this work, information about COVID-19 is provided and the situation in Arab countries and ...

Ref: Novel Coronavirus COVID-19 Strike on Arab Countries and Territories: A Situation Report I [Arch Phys Med Rehabil, 2020-03-20]

We recommend COVID-19 screening for patients with severe flu-like syndrome and protecting health-care workers from being infected.

... coronavirus disease 2019 (COVID-19) in Taiwan. As concurrently infected with Klebsiella pneumoniae and subsequently with Klebsiella aerogenes, he was exposed by a national survey of patients with critically influenza-negative pneumonia. We recommend COVID-19 screening for patients with severe flu-like syndrome and protecting health-care workers from being infected. ...

Ref: First COVID-19 mortality case in Taiwan with bacterial co-infection by national surveillance of critically ill patients with influenza-negative pneumonia [J. microbiol. immunol. infect, 2020]

RNAemia was neither detected in 3 patients without symptoms nor in 14 patients with flu-like symptoms, fever or pneumonia.

... swabs or sputum from the lower respiratory tract were tested RT-PCR positive in all patients, RNAemia was neither detected in 3 patients without symptoms nor in 14 patients with flu-like symptoms, fever or pneumonia. The only patient with RNAemia suffered from acute respiratory distress syndrome (ARDS) and was artificially ...

Ref: SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission [J. microbiol. immunol. infect, 2020-03-30]

Increased disease severity and mortality amongst individuals with respiratory viral infections are often attributed to subsequent bacterial co-infections,

... 2019 (COVID-19) co-infections, which at present, are overlooked and poorly understood (Cox et al., 2020). Increased disease severity and mortality amongst individuals with respiratory viral infections are often attributed to subsequent bacterial co-infections, accounting for approximately 95% of deaths during the 1918 Spanish flu pandemic (Morens et al., ...

Ref: Necrotizing periodontal disease: oral manifestation of COVID-19. [Oral diseases, 2020-06-07]

The clinical features are essentially the same as for any respiratory viral infections or pneumonitis.

... area with fever and cough would be diagnosed as SARS by WHO definition in 2003. The clinical features are essentially the same as for any respiratory viral infections or pneumonitis. Towards the end of the 2003 epidemics, SARS coronavirus was identified to be the culprit, ...

Ref: Severe acute respiratory symptoms and severe acute respiratory syndrome [Clin Respir J, 2013-07-08]

Since all patients shared similar clinical and laboratory findings, expanded surveillance of detailed exposure history for suspected patients and application of rapid detection tools are highly recommended.

... 41 non-COVID-19 patients were infected by particular pathogens. In general, seasonal respiratory pathogens are more prevalent than SARS-CoV-2 in symptomatic patients in non- COVID-19 endemic area during the flu season. Since all patients shared similar clinical and laboratory findings, expanded surveillance of detailed exposure history for suspected patients and application of rapid detection tools are highly recommended. ...

Ref: Featuring COVID-19 cases via screening symptomatic patients with epidemiologic link during flu season in a medical center of central Taiwan [J Microbiol Immunol Infect, 2020]

the SARS-CoV-2 may present with varying degrees of severity, from flu-like symptoms to death.

... human strains of Coronavirus are associated with about 15% of cases of the common cold, the SARS-CoV-2 may present with varying degrees of severity, from flu-like symptoms to death. It is currently believed that this deadly Coronavirus strain originated from wild animals at the ...

Ref: The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China [J Autoimmun, 2020]

Since the recoveries/deaths ratio in the last weeks significantly increased,

... co-administered darunavir and umifenovir (in patient therapies) were also recently recorded as having anti-SARS-CoV-2 effects. Since the recoveries/deaths ratio in the last weeks significantly increased, especially in China, it is clear that the experi- mental antiviral therapy, together with the ...

Ref: SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and Other Drugs for the Treatment of the New Coronavirus [Curr. med. chem, 2020]

Our U.S. healthcare system functions well but seasonal influenza outbreaks can provide unique challenges and stresses regional bed capacity of hospitals.

and employs more than 7 million people 2 . Our U.S. healthcare system functions well but seasonal influenza outbreaks can provide unique challenges and stresses regional bed capacity of hospitals.

Ref: Successful healthcare delivery using ambulatory hospitals—past, present and future [Am J Med, 2020-05-20]

The COVID-19 group had a higher rate of contact with the epidemic area within 14 days and of clustering onset than other groups.

... 14 (10.29%) of them were diagnosed as COVID-19 and respiratory syncytial virus (RSV) infections, respectively. The COVID-19 group had a higher rate of contact with the epidemic area within 14 days and of clustering onset than other groups. Fever was the most common symptom in these patients. The ratio of fever to the ...

Ref: Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing [Int J Infect Dis, 2020]

The clinical spectrum of COVID-19 is heterogeneous, ranging from mild flu-like symptoms to acute respiratory distress syndrome, multiple organ failure and death.

... period", "transmission", "clinical features", "diagnosis", "treatment", "diabetes", with interposition of the Boolean operator "AND". RESULTS: The clinical spectrum of COVID-19 is heterogeneous, ranging from mild flu-like symptoms to acute respiratory distress syndrome, multiple organ failure and death. Older age, diabetes and other comorbidities are reported as significant predictors of morbidity and mortality. ...

Ref: COVID-19 and diabetes: Knowledge in progress [Diabetes Res Clin Pract, 2020]

This Dutch study confirms that there is a (highly) significant inverse correlation between pollen count and weekly changes in medical flu consults,

... environmental factor that makes it more difficult for flu-like viruses to survive outside a host. This Dutch study confirms that there is a (highly) significant inverse correlation between pollen count and weekly changes in medical flu consults, and that there is a highly significant inverse correlation between hay fever incidence, as measured ...

The patient was negative for Flu A/B and had a negative respiratory viral panel.

... 93% on 5 L via nasal cannula. Cell counts and electrolytes were within normal limits. The patient was negative for Flu A/B and had a negative respiratory viral panel. Chest X-ray obtained showed nonspecific bibasilar airspace disease (Fig. 1) . Of note, the patient"s ...

Ref: A novel presentation of COVID-19 via community acquired infection [Visual Journal of Emergency Medicine, 2020-07-31]

In a pre-coronavirus era, respiratory infection rates for 7 biologic therapy patients were comparable to placebo.

... Information is still limited regarding the new coronavirus and its impact on chronic 6 immunosuppressive therapy patients. In a pre-coronavirus era, respiratory infection rates for 7 biologic therapy patients were comparable to placebo. 3 8 ...

Ref: COVID-19 and biologics for psoriasis: a high-epidemic area experience - Bergamo, Lombardy, Italy [J Am Acad Dermatol, 2020-05-06]

CoV-NL63 was more than twice as likely to produce symptomatic infection episodes as CoV-229E (by Definitions 1-4).

... 1-4, the majority of CoV infection episodes were asymptomatic. When stratified by type, differences emerge: CoV-NL63 was more than twice as likely to produce symptomatic infection episodes as CoV-229E (by Definitions 1-4). Definition 5, which defines symptomatic infection as the manifestation of any symptom during the 11day ...

Ref: Direct Measurement of Rates of Asymptomatic Infection and Clinical Care-Seeking for Seasonal Coronavirus [J Am Acad Dermatol, 2020-02-03]

Coronavirus disease 2019 (COVID-19) is spreading.

... BACKGROUND: Coronavirus disease 2019 (COVID-19) is spreading. Here, we summarized the composition of pathogens in fever clinic patients and analyzed the characteristics of different respiratory viral infections. METHODS: Retrospectively collected patients with definite etiological results using ...

Ref: Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing [Int J Infect Dis, 2020]

they sustained associated septic shock more frequently than COVID-19 patients.

... lower cardiac index in patients with flu-related ARDS is presumably related to septic cardiomyopathy since they sustained associated septic shock more frequently than COVID-19 patients. Depressed indices of RV systolic function and elevated central venous pressure reflecting systemic venous congestion ...

Ref: Cardiovascular phenotypes in ventilated patients with COVID-19 acute respiratory distress syndrome [Crit Care, 2020-05-18]

the infection rate is high and the mortality rate is very low.

... -OC43, -HKU1, and -NL63) will take its place next to the seasonal flu viruses, where the infection rate is high and the mortality rate is very low. In the near future, your doctor will routinely prescribe you something like "covidol" and say ...

Ref: SARS-CoV-2 will continue to circulate in the human population: an opinion from the point of view of the virus-host relationship [Inflamm Res, 2020-04-30]

however, severe cases have been reported in elderly individuals and immune compromised patients with underlying conditions.

... affects all ages. The clinical epidemiology of MERS-CoV cases showed similarity to the seasonal flu; however, severe cases have been reported in elderly individuals and immune compromised patients with underlying conditions. 9 Health-care workers are among the risk groups 2 and asymptomatic health-care workers spread illness ...

Ref: Knowledge and awareness of Middle East respiratory syndrome coronavirus among Saudi and Non-Saudi Arabian pilgrims [Int J Health Sci (Qassim), 2017]

At the present time, the virus strain appears to cause very mild illness.

... in either humans or animals. Additionally, H1N1 appears to be more contagious than seasonal influenza. At the present time, the virus strain appears to cause very mild illness. But scientists are always concerned about the intrinsic mutability of influenza viruses. At the time ...

Ref: Pandemic Influenza: Impact on Perianesthesia Nursing Areas [J Perianesth Nurs, 2009-06-03]

CoV-NL63 was more than twice as likely to produce symptomatic infection episodes as CoV-229E

Ref: Direct Measurement of Rates of Asymptomatic Infection and Clinical Care-Seeking for Seasonal Coronavirus [J Perianesth Nurs, 2020-02-03]

a respiratory disease that ranges from an asymptomatic or mild flu-like illness to severe pneumonia, multiorgan failure, and death.

... syndrome coronavirus 2 (SARS-CoV-2) is a new virus responsible for the coronavirus disease 2019 (COVID-19), a respiratory disease that ranges from an asymptomatic or mild flu-like illness to severe pneumonia, multiorgan failure, and death. Imaging might play an important role in clinical decision making by supporting rapid triage of ...

Ref: The role of the radiologist in diagnosing the COVID-19 infection. Parma experiences [Acta Biomed, 2020]

Managing this anxiety has always been a challenge, especially with the Spanish flu.

... of the illness itself and the problems caused by the anxiety that the virus triggers. Managing this anxiety has always been a challenge, especially with the Spanish flu. People with mental illness had particularly poor outcomes with the Spanish flu, often related to ...

Ref: Plagues, pandemics and epidemics in Irish history prior to COVID-19 (coronavirus): what can we learn? [Ir J Psychol Med, 2020]

Although COVID-19 leads to little or mild flu-like symptoms in the majority of affected patients,

... ongoing global health crisis due to COVID-19, caused by severe acute respiratory syndrome coronavirus 2. Although COVID-19 leads to little or mild flu-like symptoms in the majority of affected patients, the disease may cause severe, frequently lethal complications such as progressive pneumonia, acute respiratory distress ...

Ref: COVID-19 and immunomodulation in IBD [Gut, 2020]

Results did not change substantially after adjustment for time-of-day differences in the case mix of included patients

... Figure 1 ). These periods included seasonal outbreaks and the 2009 H1N1 (swine flu) pandemic. Results did not change substantially after adjustment for time-of-day differences in the case mix of included patients (adjusted ratio of 6 AM-noon vs. 6 PM-midnight: national=0.59, 95% CI=0.50-0.70). The daily changes in ...

Ref: Fevers Are Rarest in the Morning: Could We Be Missing Infectious Disease Cases by Screening for Fever Then? [Gut, 2020-05-26]

Because the virus is highly contagious, it rapidly spreads and continuously evolves in the human population.

... be a spillover of an animal coronavirus and later adapted the ability of human-to-human transmission. Because the virus is highly contagious, it rapidly spreads and continuously evolves in the human population. In this review article, we discuss the basic properties, potential origin, and evolution of the ...

Ref: COVID-19: The first documented coronavirus pandemic in history [Biomed. j. (Mumbai.Online), 2020]

Meteorological factors alone do not predict seasonality,

Ref: Pollen Explains Flu-Like and COVID-19 Seasonality [Biomed. j. (Mumbai.Online), 2020-06-07]

Although co-infection with other respiratory viruses appears to be uncommon in patients with SARS-C0V-2 infection in our community,

... Although co-infection with other respiratory viruses appears to be uncommon in patients with SARS-C0V-2 infection in our community, our data do not address whether patients who do develop co-infection experience more severe illness or an This article is protected by copyright. All rights reserved. ...

Ref: Co‐infection in SARS‐CoV‐2 infected Patients: Where Are Influenza Virus and Rhinovirus/Enterovirus? [J Med Virol, 2020-04-30]

While pandemic flu caused significant mortality in children, SARS-CoV-2 mainly kills people over 60 and with comorbidities.

... respiratory droplet, but it is thought that the mortality is higher in SARS-CoV-2 infected cases. While pandemic flu caused significant mortality in children, SARS-CoV-2 mainly kills people over 60 and with comorbidities. From the data published so far, it appears that children account for 1-5% of all ...

Ref: Impact of COVID-19 on Children and Pediatricians [Indian Pediatr, 2020-04-09]

The interference factors causing false-positive reactivity with the two methods were analyzed,

... from diabetes mellitus patients, and 14 sera from novel coronavirus infection disease 19 (COVID-19) patients. The interference factors causing false-positive reactivity with the two methods were analyzed, and the urea dissociation test was employed to dissociate the SARS-CoV-2 IgM-positive serum using the ...

Ref: A Method To Prevent SARS-CoV-2 IgM False Positives in Gold Immunochromatography and Enzyme-Linked Immunosorbent Assays [J. clin. microbiol, 2020]

The new CoV-19 spreads in the population at a rate of 0.8-3% more than normal flu and mostly affects men,

... the immune system which, if it is weak, cannot stem the infection and its symptoms. The new CoV-19 spreads in the population at a rate of 0.8-3% more than normal flu and mostly affects men, since immune genes are more expressed on the X chromosome. If CoV-19 would spread with ...

Ref: How to reduce the likelihood of coronavirus-19 (CoV-19 or SARS-CoV-2) infection and lung inflammation mediated by IL-1. [Journal of biological regulators and homeostatic agents, 2020-03-31]

That is because current environmental factors do not provide a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates.

... is uncertainty if current models for the Covid-19 pandemic should already take into account seasonality. That is because current environmental factors do not provide a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates. It is hypothesized that one major factor is overlooked: pollen count. Pollen are documented to ...

AbstractThe recent outbreak of the COVID-19 or the coronavirus flu pandemic in the world threatens to derail the very existence of humankind

... AbstractThe recent outbreak of the COVID-19 or the coronavirus flu pandemic in the world threatens to derail the very existence of humankind The planet could only ignore the challenges posed by this flu strain to its peril This analysis seeks to locate the pandemic, its challenges and probable solutions within a socio-economic, ...

Ref: COVID-19: A Socio-economic Perspective [FIIB Business Review, 2020]

causing a rapid outbreak with a moderate case fatality rate.

... deadly virus, MERS-CoV in 2012. A novel coronavirus "SARS-CoV-2" (and the disease COVID-19) emerged suddenly, causing a rapid outbreak with a moderate case fatality rate. This virus is continuing to cause health care providers grave concern due to the lack ...

Ref: Emergence of Novel Coronavirus and COVID-19: whether to stay or die out? [Crit Rev Microbiol, 2020]

Both CoVs and IAVs can cause ARDS and lead to multiple organ failure and death.

... wild animals, as well as maintaining ecological balance in the world to prevent the 150 breaking of epidemics in future. 152 The major clinical symptoms are summarized in Table 2 Both CoVs and IAVs can cause ARDS and lead to multiple organ failure and death. ...

Ref: Comparative review of respiratory diseases caused by coronaviruses and influenza A viruses during epidemic season [Microbes Infect, 2020-05-13]

In comparison, seasonal influenza normally kills fewer than 1% of affected individuals 34 .

... COVID-19 press briefing on March 3, 2020, that there is a 3.4% mortality rate globally. In comparison, seasonal influenza normally kills fewer than 1% of affected individuals 34 . Initially, at a press conference on Wednesday, January 29, 2020, and again on February 10, ...

Ref: COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus [Discoveries (Craiova), 2020-04-26]

While many provocations to the health status of individuals with frailty are random and unpredictable, 'seasonality' is not.

... While many provocations to the health status of individuals with frailty are random and unpredictable, "seasonality" is not. Over millennia, humans have adapted to survive relatively harsh climates, both by genetic adaptation and through the use of housing, clothing, and heating/cooling technologies (4) . This ability to optimise ...

Ref: Frailty and Seasonality [J Nutr Health Aging, 2020-04-17]

Here, we summarized the composition of pathogens in fever clinic patients and analyzed the characteristics of different respiratory viral infections.

Ref: Characteristics of respiratory virus infection during the outbreak of 2019 novel coronavirus in Beijing [Int J Infect Dis, 2020]

Pollen is documented to be antiviral and allergenic, play a role in immuno-activation,

... seasonality, given substantial climate differences between countries that are subject to flu-like epidemics or COVID-19. Pollen is documented to be antiviral and allergenic, play a role in immuno-activation, and seems to create a bio-aerosol lowering the reproduction number of flu-like viruses. Therefore, we ...

Ref: Pollen Explains Flu-Like and COVID-19 Seasonality [Int J Infect Dis, 2020-06-07]

However, the virus detection rate in each month was not significantly different.

... more frequently detected in the early months of the year in all regions in Indonesia. However, the virus detection rate in each month was not significantly different. The increased respiratory infections during this period may be related to the rainy season in ...

Ref: Multiple Viral Infection Detected from Influenza-Like Illness Cases in Indonesia [Biomed Res Int, 2017-01-23]

current environmental factors do not provide a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates.

... current models for the Covid-19 pandemic should already take into account seasonality. That is because current environmental factors do not provide a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates. It is hypothesized that one major factor is overlooked: pollen count. Pollen are documented to ...

Pollen are documented to invoke strong immune responses

Human coronaviruses usually cause mild upper respiratory diseases.

... Human coronaviruses usually cause mild upper respiratory diseases. However, in the past two decades, two coronaviruses transmitted from animals, SARS-CoV and MERS-CoV, have caused severe pneumonia and death in humans. In addition, since late December 2019, the COVID-19 ...

Ref: COVID-19: the First Documented Coronavirus Pandemic in History [Biomed J, 2020-05-05]

Differences were assessed using the Pearson's Chi square ( χ 2 ) statistic, and for small samples, the Fisher's exact test.

... bocavirus and differences in distribution of single and dual infections by age, sex, and season. Differences were assessed using the Pearson"s Chi square ( χ 2 ) statistic, and for small samples, the Fisher"s exact test. Association between single and mixed virus infection and admission to a general ward (GW) or ...

Ref: Pan-human coronavirus and human bocavirus SYBR Green and TaqMan PCR assays; use in studying influenza A viruses co-infection and risk of hospitalization [Infection, 2014-12-05]

The distribution of viral agents varied across age groups and month of detection.

... 15 (8.33%) human metapneumovirus (HMPV), 8 (4.44%) parainfluenza viruses (PIV) and 4 (2.22%) adenoviruses (ADV). The distribution of viral agents varied across age groups and month of detection. The positive specimens were from 168 patients [102 M, 66 F; median age (range): 64 ...

Ref: Viruses of Respiratory Tract: an Observational Retrospective Study on Hospitalized Patients in Rome, Italy [Infection, 2020]

the epidemic is more widespread than initially estimated, with cases now confirmed in multiple countries.

... Abstract Background An outbreak of Novel Coronavirus (COVID -19) in Wuhan, China, the epidemic is more widespread than initially estimated, with cases now confirmed in multiple countries. Aims The aim of the meta-analysis was to assess the prevalence of comorbidities in the COVID-19 infection patients ...

Ref: Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis [Int J Infect Dis, 2020-03-12]

Seasonal influenza viruses kill 250,000-500,000, mostly older people each year around the world [3] .

... restricted to human horde. Influenza C is isolated from humans, pigs and dogs [10] . Influenza D viruses primarily affect cattle and human population in all age groups [11] . Seasonal influenza viruses kill 250,000-500,000, mostly older people each year around the world [3] . ...

Ref: Emerging and reemerging respiratory viral infections up to Covid-19 [Turk J Med Sci, 2020-04-21]

Symptoms are generally similar to flu (fever, dry cough, headache, sore throat and runny nose),

... COVID-19 is caused by a virus named SARS-CoV-2. Symptoms are generally similar to flu (fever, dry cough, headache, sore throat and runny nose), but ~25% of patients require intensive care and 10% require mechanical ventilation [5, 6] . The case-fatality rate is variable and depends ...

Ref: COVID-19: Health prevention and control in non-healthcare settings [Occup Med (Lond), 2020-04-20]

COVID-19 can cause mild flu-like symptoms, including fever, cough, dyspnea, myalgia, and fatigue,

... There is much more to learn about the spread and severity of COVID-19. COVID-19 can cause mild flu-like symptoms, including fever, cough, dyspnea, myalgia, and fatigue, while more serious forms can cause severe pneumonia, acute respiratory distress syndrome, septic shock, and organ failure, ...

Ref: Cross-Country Comparison of Case Fatality Rates of COVID-19/SARS-COV-2 [Osong Public Health Res Perspect, 2020-04-19]

flu-like symptoms rapidly degenerating into respiratory distress, hypotension, and cardiogenic shock.

... myocardial localization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 69-year-old patient with flu-like symptoms rapidly degenerating into respiratory distress, hypotension, and cardiogenic shock. The patient was successfully treated with venous-arterial extracorporeal membrane oxygenation (ECMO) and mechanical ventilation. Cardiac ...

Ref: Myocardial localization of coronavirus in COVID-19 cardiogenic shock [Eur J Heart Fail, 2020]

We compared the research of these two coronavirus epidemics to seven other emerging viral infectious diseases as comparators.

... emerging viruses over the past two decades with emphasis on emerging coronavirus (SARS and MERS). We compared the research of these two coronavirus epidemics to seven other emerging viral infectious diseases as comparators. To this end, we used multiple bibliometric datasets, fusing them to get additional insights. Using ...

Ref: Scientometric Trends for Coronaviruses and Other Emerging Viral Infections [bioRxiv, 2020-04-09]

HCoV is widespread globally and patterns of outbreaks vary according to locations and seasonal factors [4] .

... HCoV is widespread globally and patterns of outbreaks vary according to locations and seasonal factors [4] . Our study found that HCoV prevalence among patients presenting with ARTI in Guangzhou over a 7-year period was highest in the spring and autumn (Fig. 2) . This stands in ...

Ref: Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China [Eur J Clin Microbiol Infect Dis, 2017-12-06]

We consider two different clinical settings, where availability of the different diagnostic strategies differs widely: outpatient and inpatient.

... a COVID-19 case, requiring specific testing, from upper respiratory and/or influenza-like illnesses of other aetiology. We consider two different clinical settings, where availability of the different diagnostic strategies differs widely: outpatient and inpatient. Our reasoning highlights how challenging a balanced approach to a patient with fever and flu-like ...

Ref: Does this patient have COVID-19? A practical guide for the internist [Intern. emerg. med, 2020]

Interestingly, the reported cases show different severity of symptoms, ranging from mild to severe with no symptoms in some cases.

... that needs rapid intervention as it shows high spread mortality rates within very short time. Interestingly, the reported cases show different severity of symptoms, ranging from mild to severe with no symptoms in some cases. Although very limited studies investigated the immune responses toward COVID-19, a recent study conducted by ...

Ref: The possible beneficial adjuvant effect of influenza vaccine to minimize the severity of COVID-19 [Medical Hypotheses, 2020-07-31]

the language distance between these two communities is going up week by week.

... to late May, we observe an increasing difference between them in many aspects. For example, the language distance between these two communities is going up week by week. The users in /r/China_flu care more about China-related topics, generate more racist comments, and are ...

Ref: A Tale of Two Communities: Characterizing Reddit Response to COVID-19 through /r/China_Flu and /r/Coronavirus [Medical Hypotheses, 2020-06-08]

Instead, the rate of transmission is significative higher,

... The novel coronavirus Covid-19 follows transmission route and clinical presentation of all community-acquired coronaviruses. Instead, the rate of transmission is significative higher, with a faster spread of the virus responsible of the worldwide outbreak and a significative higher ...

Ref: SARS - CoV-2: Reasons of epidemiology of severe ill disease cases and therapeutic approach using trivalent vaccine (tetanus, diphtheria and Bordetella pertussis) [Med Hypotheses, 2020]

171 (43%) did know that the common flu virus is potentially more lethal than coronavirus.

... (56.6%) participants claimed that coronavirus is actually the most dangerous virus in the world, and 171 (43%) did know that the common flu virus is potentially more lethal than coronavirus. Although a large majority of participants correctly identified sources of transmission, measures and precautions to ...

Ref: Knowledge and awareness regarding spread and prevention of COVID-19 among the young adults of Karachi [J Pak Med Assoc, 2020]

MERS-CoV was not the cause of severe CAP in any of the hospitalised pilgrims investigated.

... for a viral finding [14, 15] . Similar to our cohort, the most common respiratory virus was HRV, detected in 57.7% of positive samples, followed by FLU A in 23.1%. MERS-CoV was not the cause of severe CAP in any of the hospitalised pilgrims investigated. ...

Ref: High prevalence of common respiratory viruses and no evidence of Middle East Respiratory Syndrome Coronavirus in Hajj pilgrims returning to Ghana, 2013 [Trop Med Int Health, 2015-03-03]

Patients Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments [2] .

... beta-coronavirus, known as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), progressively spread in Italy. Patients Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments [2] . A national analysis performed in China showed that cancer patients have a five times higher ...

Ref: Cancer treatment during COVID-19 pandemic: do not postpone, do it! [Eur J Cancer, 2020-05-12]

in severe cases, patients develop pneumonia, acute respiratory distress syndrome, sepsis and septic shock, that can result in their death.

... a new coronavirus presenting a variability of flu-like symptoms including fever, cough, myalgia and fatigue; in severe cases, patients develop pneumonia, acute respiratory distress syndrome, sepsis and septic shock, that can result in their death. This infection, which was declared a global epidemic by the World Health Organization, is particularly ...

Ref: [Covid-19 in patients on dialysis: infection prevention and control strategies]. [Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2020-04-09]

No differences in the performance of the case definition or symptoms in influenza cases according to virus type were found in a recently published study [14] .

... No differences in the performance of the case definition or symptoms in influenza cases according to virus type were found in a recently published study [14] . The identified influenza virus sub-types were as following (n = 7, 955): ...

Ref: Performance of suspected influenza case definitionbefore and during the COVID-19 pandemic [Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2020-06-02]

Mild infections usually improve within a few days, but COVID-19 can cause severe pneumonia with acute respiratory distress syndrome and death.

... and has caused an international public health emergency. The most common manifestation is flu-like symptoms. Mild infections usually improve within a few days, but COVID-19 can cause severe pneumonia with acute respiratory distress syndrome and death. Gastrointestinal symptoms are less common but possible and more difficult to recognize as part of ...

Ref: Abdominal Pain: A Real Challenge in Novel COVID-19 Infection [Eur J Case Rep Intern Med, 2020-03-26]

protecting medical personnel who could contribute to dissemination of the infection and avoiding simultaneous transmission which can cause momentary health system failure 4 .

... to quarantine measures and ICU admittance, raising awareness about the seasonal flu that can maximize the number of patients visiting hospital and reaching the SARS-CoV-2 colonization acting as a vector, protecting medical personnel who could contribute to dissemination of the infection and avoiding simultaneous transmission which can cause momentary health system failure 4 . ...

Ref: Covid-19 in Brazil [Pulmonology, 2020-04-27]