¿Tiene el SARS-CoV-2 algún subtipo? De ser así, ¿cómo son?
(Does sars-cov-2 have any subtypes, and if so what are they?)
Primeras 5 respuestas:
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Six virus subtypes were predominant in the population, but all sixteen showed amino acid replacements which might have phenotypic implications.
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two subtypes (SARS-CoV-2a and -b) were confirmed within SARS-CoV-2 strains.
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Through the generated pseudovirus of SARS-CoV-2 and avian influenza virus H5 subtypes,
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five out of six SARS-CoV-2 subtypes have become either moderately or slightly more infectious, while one subtype has weakened its infectivity.
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ZJ01 has T at both sites and is currently the only known TT type.
Six virus subtypes were predominant in the population, but all sixteen showed amino acid replacements which might have phenotypic implications.
... nsp4, nsp6, nsp12, nsp13 and nsp14) cistrons, structural (spike and nucleocapsid) and accessory (ORF8) genes. Six virus subtypes were predominant in the population, but all sixteen showed amino acid replacements which might have phenotypic implications. We hypothesize that the virus subtypes detected in this study are records of the early ...
Ref: The global population of SARS-CoV-2 is composed of six major subtypes [bioRxiv, 2020-04-20]two subtypes (SARS-CoV-2a and -b) were confirmed within SARS-CoV-2 strains.
... better understand the antigenicity and immunogenicity of this virus in this study. In phylogenetic analysis, two subtypes (SARS-CoV-2a and -b) were confirmed within SARS-CoV-2 strains. These two subtypes were divided by a novel synonymous mutation of D614G. This may play ...
Ref: A Novel Synonymous Mutation of SARS-CoV-2: Is This Possible to Affect Their Antigenicity and Immunogenicity? [Vaccines, 2020-05-14]Through the generated pseudovirus of SARS-CoV-2 and avian influenza virus H5 subtypes,
... avian influenza virus H5 subtypes which can be handled in the biosafety level 2 facility. Through the generated pseudovirus of SARS-CoV-2 and avian influenza virus H5 subtypes, we successfully established a neutralization assay to quantify the neutralizing activity of antisera against the ...
Ref: Assessing the application of a pseudovirus system for emerging SARS-CoV-2 and re-emerging avian influenza virus H5 subtypes in vaccine development [Biomed J, 2020-06-06]five out of six SARS-CoV-2 subtypes have become either moderately or slightly more infectious, while one subtype has weakened its infectivity.
... 2 (ACE2) receptor following the mutations. Based on mutation-induced binding affinity changes, we reveal that five out of six SARS-CoV-2 subtypes have become either moderately or slightly more infectious, while one subtype has weakened its infectivity. We find that SARS-CoV-2 is slightly more infectious than SARS-CoV according to computed S protein-ACE2 ...
Ref: Mutations strengthened SARS-CoV-2 infectivity [Biomed J, 2020-05-27]ZJ01 has T at both sites and is currently the only known TT type.
... strains collected globally based on the base (C or T) at positions 8824 and 28247. ZJ01 has T at both sites and is currently the only known TT type. The prediction of the Furin cleavage site (FCS) and sequence alignment of the virus family ...
Ref: Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site. [Emerging microbes & infections, 2020-06-16]SARS-CoV-2 originated in China and, within three months, has evolved to an additional 10 subtypes.
... tragedy. Worldwide, SARS-CoV-2 has already infected over 3 million and has killed about 230,000 people. SARS-CoV-2 originated in China and, within three months, has evolved to an additional 10 subtypes. One particular subtype with a non-silent (Aspartate to Glycine) mutation at 614th position of the ...
Ref: Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by Human Genomic Variations that Regulate Expression of TMPRSS2 and MX1 Genes [bioRxiv, 2020-05-05]Six virus subtypes were predominant in the population,
... nsp4, nsp6, nsp12, nsp13 and nsp14) cistrons, structural (spike and nucleocapsid) and accessory (ORF8) genes. Six virus subtypes were predominant in the population, but all sixteen showed amino acid replacements which might have phenotypic implications. We hypothesize that ...
Ref: The global population of SARS-CoV-2 is composed of six major subtypes [bioRxiv, 2020-04-20]The antibodies to the S1 and RBD domains of spike protein are highly subtype-specific,
... pilot study yields several insights into cross-reactivity of common human coronavirus antibodies for SARS-CoV-2 antigens. The antibodies to the S1 and RBD domains of spike protein are highly subtype-specific, consistent with the high variability in these sequences between different human coronaviruses. Conversely, the S2 ...
Ref: Analysis of Serologic Cross-Reactivity Between Common Human Coronaviruses and SARS-CoV-2 Using Coronavirus Antigen Microarray [bioRxiv, 2020-03-25]it can be used to enrich for SARS-CoV-2 sequences without prior knowledge of type or subtype.
... contains 502 120nt ssDNA biotin-labeled probes designed based on all available SARS-CoV-2 viral sequences and it can be used to enrich for SARS-CoV-2 sequences without prior knowledge of type or subtype. Following the CDC health and safety guidelines, marked enrichment was demonstrated in a virus strain ...
Ref: High-Coverage SARS-CoV-2 Genome Sequences Acquired by Target Capture Sequencing. [Journal of medical virology, 2020-06-03](1) distinct genetic subtypes of infections in Europe,
... time. Based on publicly available data up to April 5, 2020, we show, for example: (1) distinct genetic subtypes of infections in Europe, with earlier transmission linked to subtypes prevalent in Italy with later development of subtypes specific ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]CCoV-II further divided into three subtypes, which are CCoV-IIa, CCoV-IIb and CCoV-II variant.
... that all the CCoV strains can be divided into 2 genotypes, named CCoV-I and CCoV-II. CCoV-II further divided into three subtypes, which are CCoV-IIa, CCoV-IIb and CCoV-II variant. CCoV-I and FCoV-I strains formed a clade. CCoV-IIb and TGEV strains clustered together, and CCoV-IIa ...
Ref: Etiology and genetic evolution of canine coronavirus circulating in five provinces of China, during 2018–2019 [Microb Pathog, 2020-04-18]Phylogenetic analysis of spike gene revealed a new subtype CCoV-II Variant and CCoV-IIa was the most prevalent subtype currently circulating.
... data in recent years, we sequenced 7 nearly complete genomes and 10 complete spike gene. Phylogenetic analysis of spike gene revealed a new subtype CCoV-II Variant and CCoV-IIa was the most prevalent subtype currently circulating. Moreover, we identified strain B906_ZJ_2019 shared 93.24% nucleotide identifies with previous strain A76, and both ...
Ref: Etiology and genetic evolution of canine coronavirus circulating in five provinces of China, during 2018-2019 [Microb Pathog, 2020]Coronaviruses are new viruses.
... Coronaviruses are new viruses. Although there have been many timely discoveries for this virus, there are still many things unknown [1, 3] . I designed a novel tool named the DNA nucleotide footprint plotter. ...
Ref: The application of DNA nucleotide footprint plotting in coronavirus [Inform Med Unlocked, 2020-05-21]Stroke subtypes were ischemic (4, 67%) and hemorrhagic (2, 33%).
... infection. RESULTS: Six patients were identified (5 men); median age was 69 years (range 57-82). Stroke subtypes were ischemic (4, 67%) and hemorrhagic (2, 33%). All patients but one had pre-existing vascular risk factors. One patient developed encephalopathy prior to ...
Ref: Stroke in patients with SARS-CoV-2 infection: case series [J. neurol, 2020]Patients diagnosed with any subtype of MPN and with or without cytoreductive or symptomatic therapy were evaluated.
... was terminated at the onset of the CoVID-19 pandemic in Europe to avoid potential bias. Patients diagnosed with any subtype of MPN and with or without cytoreductive or symptomatic therapy were evaluated. Due to the challenge of under-reporting observed in registries or chart reviews conducted by MPN ...
Ref: Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study [Leukemia, 2020-05-30]one subtype has weakened its infectivity.
... five out of six SARS-CoV-2 subtypes have become either moderately or slightly more infectious, while one subtype has weakened its infectivity. We find that SARS-CoV-2 is slightly more infectious than SARS-CoV according to computed S protein-ACE2 ...
Ref: Mutations strengthened SARS-CoV-2 infectivity [Leukemia, 2020-05-27]While different types of coronaviruses showed scattered distribution, all SARS-CoV-2 strains clustered together tightly.
... The phylogenetic tree was constructed using sequences from database search stage 1 and other coronaviruses. While different types of coronaviruses showed scattered distribution, all SARS-CoV-2 strains clustered together tightly. Importantly, the reference sequence was located in the middle of the SARS-CoV-2 cluster, demonstrating good ...
Ref: The establishment of reference sequence for SARS‐CoV‐2 and variation analysis [J Med Virol, 2020-03-20]five out of six SARS-CoV-2 subtypes have become either moderately or slightly more infectious,
... 2 (ACE2) receptor following the mutations. Based on mutation-induced binding affinity changes, we reveal that five out of six SARS-CoV-2 subtypes have become either moderately or slightly more infectious, while one subtype has weakened its infectivity. We find that SARS-CoV-2 is slightly more infectious ...
Ref: Mutations strengthened SARS-CoV-2 infectivity [J Med Virol, 2020-05-27]In phylogenetic analysis, two subtypes (SARS-CoV-2a and -b) were confirmed within SARS-CoV-2 strains.
... of SARS-CoV-2 to better understand the antigenicity and immunogenicity of this virus in this study. In phylogenetic analysis, two subtypes (SARS-CoV-2a and -b) were confirmed within SARS-CoV-2 strains. These two subtypes were divided by a novel synonymous mutation of D614G. This may play ...
Ref: A Novel Synonymous Mutation of SARS-CoV-2: Is This Possible to Affect Their Antigenicity and Immunogenicity? [Vaccines, 2020-05-14]In one patient the subtype was not specified.
... 3 with Miller-Fisher syndrome (MFS), and 2 with acute motor and sensory axonal neuropathy (AMSAN). In one patient the subtype was not specified. The cerebrospinal fluid (CSF) was tested for SARS-CoV-2 in 15 patients but was negative for ...
Ref: COVID-19 polyradiculitis in 24 patients without SARS-CoV-2 in the cerebro-spinal fluid. [Journal of medical virology, 2020-06-04]Typically, multiple genomes represent different subtypes of the target virus or microorganism.
... microorganism. This file contains one or more reference genomes for the target virus or microorganism. Typically, multiple genomes represent different subtypes of the target virus or microorganism. For instance, if the target virus is HPV, the genomes may comprise HPV-16, HPV-18, HPV-31, ...
Ref: A Computational Toolset for Rapid Identification of SARS-CoV-2, other Viruses, and Microorganisms from Sequencing Data [bioRxiv, 2020-05-16]RmYN02 was the closest relative of SARS-CoV-2 in most of the virus genome.
RmYN02 was the closest relative of SARS-CoV-2 in most of the virus genome.
Ref: A novel bat coronavirus closely related to SARS-CoV-2 contains natural insertions at the S1/S2 cleavage site of the spike protein [Curr Biol, 2020-05-11]we report that SARS-CoV-2 has had 4459 mutations which can be clustered into five subtypes.
... genome samples collected up to April 24, 2020 (this will be updated during the revision!), we report that SARS-CoV-2 has had 4459 mutations which can be clustered into five subtypes. We introduce mutation ratio and mutation $h$-index to characterize the protein conservativeness and unveil that ...
Ref: Decoding SARS-CoV-2 transmission, evolution and ramification on COVID-19 diagnosis, vaccine, and medicine. [Journal of chemical information and modeling, 2020-06-12]Our clustering results show that globally, there are at least five distinct subtypes of SARS-CoV-2 genomes.
... which provides the updated molecular information for the region-specific design of vaccines, drugs, and diagnoses. Our clustering results show that globally, there are at least five distinct subtypes of SARS-CoV-2 genomes. While, in the U.S., there are at least three significant SARS-CoV-2 genotypes. We introduce mutation ...
Ref: Decoding SARS-CoV-2 transmission, evolution and ramification on COVID-19 diagnosis, vaccine, and medicine [Journal of chemical information and modeling, 2020-04-29]SARS-CoV-2, which is responsible for the COVID-19 pandemic, is a type of beta-COV.
... SARS-CoV-2, which is responsible for the COVID-19 pandemic, is a type of beta-COV. Genomic characterization studies of the new strain have indicated an 89% nucleotide match with bat SARS-like CoVZXC21 [3, 6] . There is also an 82% nucleotide match with the human ...
Ref: Coronavirus (COVID-19): A Review of Clinical Features, Diagnosis, and Treatment [Cureus, 2020-03-21]The strains infecting humans belong to either alpha and beta genera of coronavirus.
... The strains infecting humans belong to either alpha and beta genera of coronavirus. The alphacoronavirus contains human coronavirus 229E (HCoV-229E) and HCoV-NL63, while the betacoronavirus contains HCoV-OC43, and HCoV-HKU1, middle east respiratory syndrome coronavirus (MERS-CoV), SARS-CoV and SARS-CoV-2 11 . It is known ...
Ref: CD8+ T cell cross-reactivity against SARS-CoV-2 conferred by other coronavirus strains and influenza virus [bioRxiv, 2020-05-20]Molecular phylogenetic analysis revealed that these RBD mutations cluster into distinct phyletic clades among global subtypes of SARS-CoV-2
... mutations were located in the Receptor Binding Domain (RBD) region that directly engages host ACE2. Molecular phylogenetic analysis revealed that these RBD mutations cluster into distinct phyletic clades among global subtypes of SARS-CoV-2 implying possible emergence of novel sublineages of the strain. Structure-guided homology modelling and docking analysis ...
Ref: Structural and Functional Implications of Spike Protein Mutational Landscape in SARS-CoV-2 [bioRxiv, 2020-06-13]Such potential evolution direction may promote the appearance of mild subtype of COVID-19.
... may adopt a similar mechanism by depending on Furin for invasion as HJU1 and OC43. Such potential evolution direction may promote the appearance of mild subtype of COVID-19. is the author/funder, who has granted medRxiv a license to display the preprint in (which ...
Ref: Virus strain of a mild COVID-19 patient in Hangzhou representing a new trend in SARS-CoV-2 evolution related to Furin cleavage site [bioRxiv, 2020-03-13]SARS-CoV-2 has had 4459 mutations which can be clustered into five subtypes.
... up to April 24, 2020 (this will be updated during the revision!), we report that SARS-CoV-2 has had 4459 mutations which can be clustered into five subtypes. We introduce mutation ratio and mutation $h$-index to characterize the protein conservativeness and unveil that ...
Ref: Decoding SARS-CoV-2 transmission, evolution and ramification on COVID-19 diagnosis, vaccine, and medicine. [Journal of chemical information and modeling, 2020-06-12]ACE2 is the binding site for SARS-CoV-2, mediating entry of the virus into cells (4) .
... the context of electronic cigarettes (e-cigarette), heat-not-burn device (IQOS) or waterpipe exposure to human airways. ACE2 is the binding site for SARS-CoV-2, mediating entry of the virus into cells (4) . Binding affinity between the spike (S) proteins of the virus and ACE2 on respiratory cells ...
Ref: COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection? [Eur Respir J, 2020-05-19]Soluble cluster of differentiation (CD) 14 subtype (sCD14-ST; 64 amino acids, 13 kDa),
... Soluble cluster of differentiation (CD) 14 subtype (sCD14-ST; 64 amino acids, 13 kDa), also termed presepsin (PSP), a small soluble peptide generated from soluble CD14, is known to function as a regulatory factor that can modulates immune responses by interacting with T and ...
Ref: cord_uid yok3icrn Presepsin in risk stratification of SARS-CoV-2... yok3icrn Presepsin in risk stratification of SARS-CoV-2... Name: title, dtype: object [Eur Respir J, cord_uid yok3icrn 2020-04-22 yok3icrn 2020-04-22 Name: publish_time, dtype: object]CoVs are divided into alpha, beta, gamma, and delta groups,
... enveloped viruses with a positive-sense, single-stranded RNA genome belonging to the Coronaviridae family [1] . CoVs are divided into alpha, beta, gamma, and delta groups, and the beta group is further composed of A, B, C, and D subgroups [2] ...
Ref: In-silico nucleotide and protein analyses of S-gene region in selected zoonotic coronaviruses reveal conserved domains and evolutionary emergence with trajectory course of viral entry from SARS-CoV2 genomic data [Eur Respir J, 2020-05-06]Recent reports of Guillain-Barré Syndrome associated with COVID-19 have described both the axonal and demyelinating subtypes.
... • Recent reports of Guillain-Barré Syndrome associated with COVID-19 have described both the axonal and demyelinating subtypes. • In this letter , I highlight features that suggest a predominantly axonal rather than demyelinating electrophysiology in these cases. ...
Ref: Does COVID-19 cause axonal GBS? [J Clin Neurosci, 2020-05-23]207 early subtypes of the virus.
... One of the genomes isolated in Turkey (EPI-ISL-428718) clustered together with the 207 early subtypes of the virus. This isolate contains T at the position 8782, which is a 208 characteristic of the S-type; however, it ...
Ref: Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey [bioRxiv, 2020-06-10]the beta group is further composed of A, B, C, and D subgroups [2] .
... Coronaviridae family [1] . CoVs are divided into alpha, beta, gamma, and delta groups, and the beta group is further composed of A, B, C, and D subgroups [2] . The virus belongs to the 2B group of the betacoronavirus family, which includes SARS-CoV and ...
Ref: In-silico nucleotide and protein analyses of S-gene region in selected zoonotic coronaviruses reveal conserved domains and evolutionary emergence with trajectory course of viral entry from SARS-CoV2 genomic data [bioRxiv, 2020-05-06]both clade 7.2 of subtype H5 highly pathogenic avian influenza virus and subtype H7N9 avian influenza virus
... elimination of three human influenza viruses which circulated worldwide for years before the pandemics. Moreover, both clade 7.2 of subtype H5 highly pathogenic avian influenza virus and subtype H7N9 avian influenza virus circulated in poultry in China for years, and they have been virtually eliminated through mass ...
Ref: Potential for elimination of SAR-CoV-2 through vaccination as inspired by elimination of multiple influenza viruses through natural pandemics or mass vaccination [J. med. virol, 2020]SARS-CoV-2 ORF8 appears divergent from other previously characterized 241 SARS-related coronaviruses [5, 40] .
... sequence feature does not appear to have been conserved in 240 SARS-CoV-2, and, in general, SARS-CoV-2 ORF8 appears divergent from other previously characterized 241 SARS-related coronaviruses [5, 40] . Previous entropy-based analysis of earlier and smaller SARS-CoV-2 242 sequence data sets have suggested that ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]We revealed that both proteins were highly decorated with specific proportions of N-glycan subtypes.
... this study, post-translational modification (PTM) of recombinant HCoV-19 S and hACE2 were characterized by LC-MSMS. We revealed that both proteins were highly decorated with specific proportions of N-glycan subtypes. Out of 21 possible glycosites in HCoV-19 S protein, 20 were confirmed completely occupied by ...
Ref: Mass spectrometry analysis of newly emerging coronavirus HCoV-19 spike S protein and human ACE2 reveals camouflaging glycans and unique post-translational modifications [bioRxiv, 2020-04-29]all SARS-CoV-2 strains clustered together tightly.
... database search stage 1 and other coronaviruses. While different types of coronaviruses showed scattered distribution, all SARS-CoV-2 strains clustered together tightly. Importantly, the reference sequence was located in the middle of the SARS-CoV-2 cluster, demonstrating good ...
Ref: The establishment of reference sequence for SARS‐CoV‐2 and variation analysis [J Med Virol, 2020-03-20]Pure ground-glass opacity was the most prevalent sub-type of ground-glass opacity after symptom onset
... peaked (30/78 [38%]) on illness days 12-17, and became the second most predominant pattern thereafter. Pure ground-glass opacity was the most prevalent sub-type of ground-glass opacity after symptom onset (20/50 [40%] to 20/28 [71%]). The percentage of ground-glass opacity with irregular linear opacity peaked ...
Ref: Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study [Radiology, 2020]there are at least five distinct subtypes of SARS-CoV-2 genomes.
... for the region-specific design of vaccines, drugs, and diagnoses. Our clustering results show that globally, there are at least five distinct subtypes of SARS-CoV-2 genomes. While, in the U.S., there are at least three significant SARS-CoV-2 genotypes. We introduce mutation ...
Ref: Decoding SARS-CoV-2 transmission, evolution and ramification on COVID-19 diagnosis, vaccine, and medicine [Radiology, 2020-04-29]Lung cancer patients in each age stage, subtype, and pathological stages are susceptible to SARS-CoV-2 infection,
... TMPRSS2 in each subtype and pathological stages of two common lung cancers, LUAD and LUSC. Lung cancer patients in each age stage, subtype, and pathological stages are susceptible to SARS-CoV-2 infection, except for the primitive subtype of LUSC, and were verified by meta-analysis, gene expression omnibus ...
Ref: Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection [Mol Cancer, 2020-04-28]has evolved to an additional 10 subtypes.
... million and has killed about 230,000 people. SARS-CoV-2 originated in China and, within three months, has evolved to an additional 10 subtypes. One particular subtype with a non-silent (Aspartate to Glycine) mutation at 614th position of the ...
Ref: Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by Human Genomic Variations that Regulate Expression of TMPRSS2 and MX1 Genes [bioRxiv, 2020-05-05]Five clades could be identified and labelled, corresponding to the Full genome tree delivered by GISAID (see Figure 1 ).
... that occur during viral cultivation or the infection by multi-strain of coronavirus. Table S1 ). Five clades could be identified and labelled, corresponding to the Full genome tree delivered by GISAID (see Figure 1 ). In Figure 2 , we found two peaks in genome sequencing depths, one covering the ...
Ref: A High-Coverage SARS-CoV-2 Genome Sequence Acquired by Target Capture Sequencing [bioRxiv, 2020-04-15]At the highest level, we assess the geographic distribution of SARS-CoV-2 subtypes,
... which may be any base, we use the generated symbol to correct the original one. At the highest level, we assess the geographic distribution of SARS-CoV-2 subtypes, and, in turn, we count 170 the frequency of unique ISMs per location and build ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]These challenges include improvements to the manufacturing processes, as well as enhancements to immunogenicity in order to elicit protective immunity to multiple variants and subtypes of influenza virus.
... cell expression systems. Although considerable progress has been achieved, including demonstration of safety and immunogenicity of H7N9 VLPs in the human clinical trials, the remaining challenges need to be addressed. These challenges include improvements to the manufacturing processes, as well as enhancements to immunogenicity in order to elicit protective immunity to multiple variants and subtypes of influenza virus. ...
Ref: Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development [Viruses, 2020]Any subtypes with a relative abundance that never goes above 2.5% for any date are collapsed into 'OTHER' category per location.
... obtained no later than a certain date (as provided in the sequence metadata) together and compute the relative abundance (i.e., frequency) of corresponding subtypes. Any subtypes with a relative abundance that never goes above 2.5% for any date are collapsed into "OTHER" category per location. The following formula illustrates this calculation: ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]clustered together with the 207 early subtypes of the virus.
... One of the genomes isolated in Turkey (EPI-ISL-428718) clustered together with the 207 early subtypes of the virus. This isolate contains T at the position 8782, which is a 208 characteristic of the S-type; however, it has T at the ...
Ref: Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey [bioRxiv, 2020-06-10]primitive subtype of LUSC.
... each age stage, subtype, and pathological stage are susceptible to SARS-CoV-2 infection, except for the primitive subtype of LUSC. LUAD patients are more susceptible to SARS-CoV-2 infection than LUSC patients. The findings are unanimous ...
Ref: Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection [Mol Cancer, 2020]Moreover, both clade 7.2 of subtype H5 highly pathogenic avian influenza virus and subtype H7N9 avian influenza virus
... to elimination of three human influenza viruses which circulated worldwide for years before the pandemics. Moreover, both clade 7.2 of subtype H5 highly pathogenic avian influenza virus and subtype H7N9 avian influenza virus circulated in poultry in China for years, and they have been virtually eliminated through mass ...
Ref: Potential for elimination of SAR-CoV-2 through vaccination as inspired by elimination of multiple influenza viruses through natural pandemics or mass vaccination [J. med. virol, 2020]Seven respiratory RNA viruses and three subtypes of Influenza A virus had been used to test capabilities of CATCH on detection and quantification.
... that was a mNGS method based on RNA and DNA hybrid tagmentation via Tn5 transposon. Seven respiratory RNA viruses and three subtypes of Influenza A virus had been used to test capabilities of CATCH on detection and quantification. Analytical performance of SARS CoV 2 and Influenza A virus had been determined with reference ...
Ref: Laboratory validation of an RNA/DNA hybrid tagmentation based mNGS workflow on SARS-CoV-2 and other respiratory RNA viruses detection [J. med. virol, 2020-05-14]distinct genetic subtypes of infections in Europe, with earlier transmission linked to subtypes prevalent in Italy with later development of subtypes specific to other countries over time;
... Based on publicly available data up to April 5, 2020, we show, for example: (1) distinct genetic subtypes of infections in Europe, with earlier transmission linked to subtypes prevalent in Italy with later development of subtypes specific to other countries over time; (2) within the United States, the emergence of an endogenous U.S. subtype that is distinct ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]The most common subtypes of HCoV were HCoV-229E (33.80%) and HCoV-HKU1
... samples, respectively), and the detection frequencies of these viruses were further increased in immunosuppressed patients. The most common subtypes of HCoV were HCoV-229E (33.80%) and HCoV-HKU1 (32.39%). A sharp increase in the detection frequencies of HCoV-229E and HCoV-HKU1 over several months ...
Ref: High incidence but low burden of coronaviruses and preferential associations between respiratory viruses. [Journal of clinical microbiology, 2013]classified LUSC into four subtypes, including the primitive, classical, secretory and basal subtypes [4] .
... subtypes including terminal respiratory unit (TRU), proximal inflammatory (PI), proximal proliferative (PP) [3] , and classified LUSC into four subtypes, including the primitive, classical, secretory and basal subtypes [4] . These subtypes have different survival outcomes and susceptible to drugs and viruses. We profiled the ...
Ref: Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection [Mol Cancer, 2020-04-28]A total of 281 candidates of different courses of COVID-19 independent of cell subtypes were identified,
... Signatures (LINCS) [21] , a drug perturbation database, to identify potential therapies for COVID-19 disease. A total of 281 candidates of different courses of COVID-19 independent of cell subtypes were identified, 10 of which were in clinical trials of COVID-19, including lopinavir/ritonavir [22] , dexamethasone, niclosamide, ...
Ref: Identification of Repurposal Drugs and Adverse Drug Reactions for Various Courses of Coronavirus Disease 2019 (COVID-19) Based on Single-cell RNA Sequencing Data [Mol Cancer, 2020-05-16]They describe two distinct patterns of respiratory COVID-19 (type L, low elastance and type H, high elastance) [2] .
... . We therefore read the editorial written by Gattinoni et al. [2] with great interest. They describe two distinct patterns of respiratory COVID-19 (type L, low elastance and type H, high elastance) [2] . However, there is a "hole" in their argument. A series of patients with COVID-19, also ...
Ref: Rethinking the respiratory paradigm of COVID-19: a ‘hole’ in the argument [Intensive Care Med, 2020-06-02]The molecular heterogeneity of SARS-CoV-2 subtypes, 7 could also have an effect on the sensitivity and specificity of serologic assays.
... non-infectious status; there may be continuing active viral shedding, particularly if their antibodies are non-neutralizing. The molecular heterogeneity of SARS-CoV-2 subtypes, 7 could also have an effect on the sensitivity and specificity of serologic assays. The imperfect performance of comparable, more established, serologic tests for other diseases (eg, toxoplasma IgM) ...
Ref: Double-Edged Spike—Are SARS-CoV-2 Serologic Tests Safe Right Now? [Lab Med, 2020-04-23]causative viruses are SARS-CoV and MERS-CoV, respectively.
... diseases, severe acute respiratory syndrome and Middle East respiratory syndrome (SARS and MERS), of which causative viruses are SARS-CoV and MERS-CoV, respectively. These three CoVs resulting diseases also share many clinical symptoms with other respiratory diseases caused ...
Ref: Comparative review of respiratory diseases caused by coronaviruses and influenza A viruses during epidemic season [Microbes Infect, 2020-05-13]we have also uncovered significant differences in 347 cell subtypes expressing ACE2 between human and monkey.
... COVID-19 2 . By comparing our dataset with publicly 346 available human single-cell RNA-seq data, we have also uncovered significant differences in 347 cell subtypes expressing ACE2 between human and monkey. We showed different expression 348 patterns for ACE2 in the lung, where the highest levels ...
Ref: Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19 [bioRxiv, 2020-04-23]However, the viral population is not homogenous and other clades like B4 also exist.
... West Bengal in Eastern India indicate a selective sweep of the A2a clade of SARS-Cov-2. However, the viral population is not homogenous and other clades like B4 also exist. We have also detected emergence of mutations in the important regions of the viral genome ...
Ref: Mutations in SARS-CoV-2 viral RNA identified in Eastern India: Possible implications for the ongoing outbreak in India and impact on viral structure and host susceptibility [J Biosci, 2020-06-04]Influenza A viruses are further divided into subtypes based on the surface proteins of the particular virus.
... pathogen for human disease and is the only influenza virus that has historically caused pandemics. Influenza A viruses are further divided into subtypes based on the surface proteins of the particular virus. These proteins are called hemagglutinin (H) and neuraminidase (N), which determine host immunity and subtype ...
Ref: Pandemic Influenza: Impact on Perianesthesia Nursing Areas [J Perianesth Nurs, 2009-06-03]the primitive subtype of LUSC.
... in each age stage, subtype, and pathological stage are susceptible to SARS-CoV-2 infection, except for the primitive subtype of LUSC. LUAD patients are more susceptible to SARS-CoV-2 infection than LUSC patients. The findings are unanimous ...
Ref: Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection [Mol Cancer, 2020]The impacts of cancer subtypes and treatment on COVID-19 infection are unclear.
... distinguished from the general population because of their deficient immune status and intensive anti-tumor treatment. The impacts of cancer subtypes and treatment on COVID-19 infection are unclear. Case Presentation: We here report the case of a primary mediastinal large B-cell lymphoma patient ...
Ref: A Primary Mediastinal Large B-Cell Lymphoma Patient With COVID-19 Infection After Intensive Immunochemotherapy: A Case Report [Front Oncol, 2020-05-22]Patients with COVID-19 commonly present with sensory neurological symptoms that include anosmia and/or loss of taste.
... a similar mechanism may underlie the multiple neurological effects of SARS-CoV-2 infection within the CNS. Patients with COVID-19 commonly present with sensory neurological symptoms that include anosmia and/or loss of taste. It has been proposed that the olfactory epithelium within the nasal cavity represents an early-stage ...
Ref: A Novel Vaccine Employing Non-Replicating Rabies Virus Expressing Chimeric SARS-CoV-2 Spike Protein Domains: Functional Inhibition of Viral/Nicotinic Acetylcholine Receptor Complexes [Med Sci Monit, 2020-05-28]The two highly pathogenic viruses, that is, SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV),
... Netherlands) or the organization (eg, HKU = Hong Kong University) in which they were identified. The two highly pathogenic viruses, that is, SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), were named primarily according to the key features of disease caused. [3] The genomic sequences ...
Ref: Voice from China: nomenclature of the novel coronavirus and related diseases [Chin Med J (Engl), 2020-05-05]classified LUSC into four subtypes,
... subtypes including terminal respiratory unit (TRU), proximal inflammatory (PI), proximal proliferative (PP) [3] , and classified LUSC into four subtypes, including the primitive, classical, secretory and basal subtypes [4] . These subtypes have different survival ...
Ref: Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection [Mol Cancer, 2020-04-28]These clades may be referred to by a variety of terms, such as 'subtypes', 'genotypes', 'groups',
... into distinct "clades", each of which corresponds to a monophyletic group on a phylogenetic tree. These clades may be referred to by a variety of terms, such as "subtypes", "genotypes", "groups", depending on the taxonomic level under investigation or the established scientific literature for the virus ...
Ref: A dynamic nomenclature proposal for SARS-CoV-2 to assist genomic epidemiology [bioRxiv, 2020-04-19]the fomite samples were divided into six subtypes for further analysis:
... In addition, the fomite samples were divided into six subtypes for further analysis: "Electronic 227 devices", "Knobs and handles", "Plants and animals", "Furniture and furnishings", "Foods and 228 drinks" and "Clothing". Table 4 shows the results of PCR analysis within the ...
Ref: SARS-CoV-2 in environmental samples of quarantined households [bioRxiv, 2020-06-02]27 of which was genotype D, 2 of which was genotype B and others genotype, including genotype E, F and G, were not detected.
... RDRP and N gene were obtained from 29 HCoV-OC43 positive samples. According to the sequence-analysis, 27 of which was genotype D, 2 of which was genotype B and others genotype, including genotype E, F and G, were not detected. The result indicated that the genotype D may be the dominant genotype. Further analysis of ...
Ref: [Molecular epidemiological study of human coronavirus OC43 in Shanghai from 2009-2016]. [Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2018]We describe a method to instead efficiently identify and label genetic variants, or “subtypes” of SARS-CoV-2.
... to the individual’s exposure location and sample date. But, there are over 30,000 bases in the full SARS-CoV-2 genome — so tracking genetic variants on a whole-sequence basis becomes unwieldy. We describe a method to instead efficiently identify and label genetic variants, or “subtypes” of SARS-CoV-2. ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]Epithelial cells across these different tissues showed the highest expression for the host factors ACE2 and TMPRSS2 required for viral entry 2 .
... datasets, we defined gene expression for 141 cell types including cell subtypes (Fig. 1 ). Epithelial cells across these different tissues showed the highest expression for the host factors ACE2 and TMPRSS2 required for viral entry 2 . In adult lung, alveolar type 1 and 2, as well as ciliated epithelial cells co-expressed ...
Ref: Cell-Type-Specific Expression of Renin-Angiotensin-System Components in the Human Body and Its Relevance to SARS-CoV-2 Infection [bioRxiv, 2020-04-11]somatostatin receptor subtype 2 (sst(2)) overexpressing tumors.
... the 1980s, the (111)In-labeled somatostatin analog OctreoScan (Covidien, Hazelwood, MO) was developed for imaging of somatostatin receptor subtype 2 (sst(2)) overexpressing tumors. On the basis of this success, peptide receptor radionuclide therapy (PRRT) was developed using similar ...
Ref: Preclinical and clinical studies of peptide receptor radionuclide therapy. [Seminars in nuclear medicine, 2010]the viral population is not homogenous and other clades like B4 also exist.
... Bengal in Eastern India indicate a selective sweep of the A2a clade of SARS-Cov-2. However, the viral population is not homogenous and other clades like B4 also exist. We have also detected emergence of mutations in the important regions of the viral genome ...
Ref: Mutations in SARS-CoV-2 viral RNA identified in Eastern India: Possible implications for the ongoing outbreak in India and impact on viral structure and host susceptibility [J Biosci, 2020-06-04]Five clades could be identified and labelled,
... that occur during viral cultivation or the infection by multi-strain of coronavirus. Table S1 ). Five clades could be identified and labelled, corresponding to the Full genome tree delivered by GISAID (see Figure 1 ). In Figure ...
Ref: A High-Coverage SARS-CoV-2 Genome Sequence Acquired by Target Capture Sequencing [J Biosci, 2020-04-15]distinct genetic subtypes of infections in Europe,
... Based on publicly available data up to April 5, 2020, we show, for example: (1) distinct genetic subtypes of infections in Europe, with earlier transmission linked to subtypes prevalent in Italy with later development of subtypes specific ...
Ref: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers [bioRxiv, 2020-04-20]the 207 early subtypes of the virus.
... One of the genomes isolated in Turkey (EPI-ISL-428718) clustered together with the 207 early subtypes of the virus. This isolate contains T at the position 8782, which is a 208 characteristic of the S-type; however, it has ...
Ref: Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey [bioRxiv, 2020-06-10]The 'S' protein in SARS-CoV-2 is longer than SARS-CoV and MERS-CoV.
... S gene of SARS-CoV-2 has low sequence identity with other Betacoronaviruses ( Figure 1B ). The "S" protein in SARS-CoV-2 is longer than SARS-CoV and MERS-CoV. Most importantly are the difference in the receptor-binding domain between the new SARS-CoV-2 and the ...
Ref: COVIDier: A Deep-learning Tool For Coronaviruses Genome And Virulence Proteins Classification [bioRxiv, 2020-05-04]Influenza A virus has many subtypes based on the type of virus surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA).
... Avian influenza is a poultry disease caused by influenza A virus infection. Influenza A virus has many subtypes based on the type of virus surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Wild aquatic birds are the primary natural host of influenza A virus, and 16 HAs (H1-H16) and 9 ...
Ref: Rapid detection of anti-H5 avian influenza virus antibody by fluorescence polarization immunoassay using a portable fluorescence polarization analyzer [Sens Actuators B Chem, 2020-08-01]Our results showed the enriched expression of all subtypes of proximal tubule cells of kidney and low but detectable levels of expression in bladder epithelial cells.
... in-house to evaluate ACE2 gene expressions in all cell types in healthy kidneys and bladders. Our results showed the enriched expression of all subtypes of proximal tubule cells of kidney and low but detectable levels of expression in bladder epithelial cells. These results indicated the urinary system is a potential route for 2019-nCoV infection, along with ...
Ref: Single-cell Analysis of ACE2 Expression in Human Kidneys and Bladders Reveals a Potential Route of 2019-nCoV Infection [bioRxiv, 2020-02-18]SARS-CoV-2 belongs to the subgenus Sarbecovirus (β-CoV lineage B),
... causing more than 150,000 confirmed cases and thousands of deaths by March 15, 2020 . SARS-CoV-2 belongs to the subgenus Sarbecovirus (β-CoV lineage B), and shares 79% of sequence with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), but only 50% ...
Ref: Association of Diabetes Mellitus with Disease Severity and Prognosis in COVID-19: A Retrospective Cohort Study [Diabetes Res Clin Pract, 2020-05-22]Soluble cluster of differentiation (CD)14 subtype
... pneumonia, is the leading complication of the respiratory Coronavirus disease 2019 (COVID-19), recently renamed SARS-CoV-2. Soluble cluster of differentiation (CD)14 subtype (sCD14-ST also termed presepsin PSP) is a regulatory factor that modulates immune responses by interacting ...
Ref: Presepsin in risk stratification of SARS-CoV-2 patients [Clin Chim Acta, 2020]COVID-19 (positive control) and four throat swab samples from patients without COVID-19 (negative controls), respectively.
... nasopharyngeal swab samples (cycle threshold [Ct] values: 32.36, 36.72, and 38.44) from patients diagnosed with COVID-19 (positive control) and four throat swab samples from patients without COVID-19 (negative controls), respectively. Moreover, based on these high-quality sequences, we discuss the heterozygosity and viral expression during coronavirus ...
Ref: High-Coverage SARS-CoV-2 Genome Sequences Acquired by Target Capture Sequencing. [Journal of medical virology, 2020-06-03]Three major SARS-CoV-2 clades known as clade G, V, and S have emerged,
... Three major SARS-CoV-2 clades known as clade G, V, and S have emerged, showing 66 a different geographical prevalence [10] . The most frequent mutation detected so far 67 defines the G clade and causes an aminoacidic change, aspartate (D) or glycine (G), ...
Ref: coronapp: A Web Application to Annotate and Monitor SARS-CoV-2 Mutations [bioRxiv, 2020-06-01]Betacoronavirus contains four subgroups, named 2a, 2b, 2c and 2d.
... genome sequence analyses, coronaviruses are phylogenetically divided into three genera known as Alph-, Beta-and Gammacoronavirus. Betacoronavirus contains four subgroups, named 2a, 2b, 2c and 2d. A fourth genera, provisionally named Deltacoronavirus, comprises a number of recently identified coronaviruses mainly from ...
Ref: A novel human coronavirus: Middle East respiratory syndrome human coronavirus [Sci China Life Sci, 2013-08-07]During the second year, all subtype B-strains were B2, and 5 out of the 13 subtypes A resulted to be A2.
... out of the 12 infected subjects, and no subtype B2 out of the 6 B-strains. During the second year, all subtype B-strains were B2, and 5 out of the 13 subtypes A resulted to be A2. For the 28 hCoV infections, 11 samples (39.3%) tested positive for hCoV-OC43, 10 (35.7%) for ...
Ref: Two‐year prospective study of single infections and co‐infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease [J Med Virol, 2008-02-22]the diverse TUs were seen among the 291 subtypes.
... H5Nx subtypes showed similar transduction unit (TU) within 10 6 to 10 8 290 TU/ml in MDCK cells (Fig. 3c) although the diverse TUs were seen among the 291 subtypes. We thus successfully transduced pseudovirions of re-emerging avian 292 ...
Ref: Assessing the application of a pseudovirus system for emerging SARS-CoV-2 and re-emerging avian influenza virus H5 subtypes in vaccine development [Biomed J, 2020-06-06]During the past several decades, subtypes H1N1 and H3N2 have been circulating worldwide [28] .
... . Primers and nfo probe were designed according to the alignment of matrix gene sequences. During the past several decades, subtypes H1N1 and H3N2 have been circulating worldwide [28] . According to the latest influenza surveillance [29] , H3N2 and A(H1N1) pdm09 accounted for the ...
Ref: Reverse transcription recombinase polymerase amplification with lateral flow dipsticks for detection of influenza A virus and subtyping of H1 and H3 [Mol Cell Probes, 2018-10-27]CCoV-II further divided into three subtypes,
... that all the CCoV strains can be divided into 2 genotypes, named CCoV-I and CCoV-II. CCoV-II further divided into three subtypes, which are CCoV-IIa, CCoV-IIb and CCoV-II variant. CCoV-I and FCoV-I strains formed a clade. CCoV-IIb ...
Ref: Etiology and genetic evolution of canine coronavirus circulating in five provinces of China, during 2018–2019 [Microb Pathog, 2020-04-18]SARS-CoV-2 has a great similarity with to SARS-CoV
... f has rapidly evolved from an epidemic outbreak to a pandemic that affects virtually everyone. SARS-CoV-2 has a great similarity with to SARS-CoV and invades host human cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor [1] ...
Ref: Selective CD8 cell reduction by SARS-CoV-2 is associated with a worse prognosis and systemic inflammation in COVID-19 patients [Clin Immunol, 2020-05-29]In birds, type A consists of subtypes H1-18 and N1-11 with many strains within and among the subtypes.
... Information (NCBI) database. In higher animals, influenza genus include type A, B, C & D. In birds, type A consists of subtypes H1-18 and N1-11 with many strains within and among the subtypes. The subtypes have a wide host range including avian, tiger, leopard, seal and human among ...
Ref: The potential of putative zinc-binding motifs of haemagglutinin A (HA) protein for categorization and prediction of pathogenicity of H5 subtypes of avian influenza virus [Med Hypotheses, 2020-05-30]ACE2 is the binding site for SARS-CoV-2,
... the context of electronic cigarettes (e-cigarette), heat-not-burn device (IQOS) or waterpipe exposure to human airways. ACE2 is the binding site for SARS-CoV-2, mediating entry of the virus into cells (4) . Binding affinity between the spike (S) ...
Ref: COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection? [Eur Respir J, 2020-05-19]Tang et al. have reported two different strains of SARS-Cov-2: L and S subtypes, with S subtype being the ancestral one.
... selection pressures can derive an emergence of variant strain and/or the survival of the fittest. Tang et al. have reported two different strains of SARS-Cov-2: L and S subtypes, with S subtype being the ancestral one. However, the progenic L subtype presents higher transmissibility [44] . In addition, a recent Chinese ...
Ref: A Comprehensive Review of Severe Acute Respiratory Syndrome Coronavirus 2 [Cureus, 2020-05-03]intensive research at a molecular level is required to characterize the subtypes of SARS-CoV-2 prevalent in Egypt.
... so as to allow policy makers to plan sound prevention strategies, adjust the length bias for the effective implementation of surveillance programs, and to predict prognosis and evaluate interventions. Moreover, intensive research at a molecular level is required to characterize the subtypes of SARS-CoV-2 prevalent in Egypt. ...
Ref: Individuals with covert severe acute respiratory syndrome coronavirus 2 infection: Are they a critical booby-trap? [Revista da Sociedade Brasileira de Medicina Tropical, 2020-06-01]While, in the U.S., there are at least three significant SARS-CoV-2 genotypes.
... clustering results show that globally, there are at least five distinct subtypes of SARS-CoV-2 genomes. While, in the U.S., there are at least three significant SARS-CoV-2 genotypes. We introduce mutation hindex and mutation ratio to characterize conservative and non-conservative proteins and genes. ...
Ref: Decoding SARS-CoV-2 transmission, evolution and ramification on COVID-19 diagnosis, vaccine, and medicine [Revista da Sociedade Brasileira de Medicina Tropical, 2020-04-29]multiple subtypes of influenza, adenovirus, metapneumovirus, parainfluenza, and respiratory syncytial virus
... epidemic coronaviruses including SARS-CoV-2, SARS-CoV, and MERS-CoV, common cold coronaviruses (HKU1, OC43, NL63, 229E), and multiple subtypes of influenza, adenovirus, metapneumovirus, parainfluenza, and respiratory syncytial virus as listed in Supplementary Table 2 . The SARS-CoV-2 antigens on this array include spike ...
Ref: Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray [bioRxiv, 2020-04-17]The common 133 cold, SARS-CoV-1, and SARS-CoV-2 fall under the same coronavirus family;
... treating influenza 132 with very large amounts of vitamin C has been practiced for decades. The common 133 cold, SARS-CoV-1, and SARS-CoV-2 fall under the same coronavirus family; hence, 134 are regarded as the same viral type. 22 Therefore, vitamin C may be ...
Ref: Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective [J Tradit Complement Med, 2020-05-30]Mixed infection of different CCoV subtypes exists extensively.
... (CPV), canine astrovirus (CaAstV), canine kobuvirus (CaKV), Torque teno canis virus (TTCaV) were ubiquitous existed. Mixed infection of different CCoV subtypes exists extensively. Considering the limited sequences data in recent years, we sequenced 7 nearly complete genomes and ...
Ref: Etiology and genetic evolution of canine coronavirus circulating in five provinces of China, during 2018-2019 [Microb Pathog, 2020]clade 7.2 of subtype H5 highly pathogenic avian influenza virus and subtype H7N9 avian influenza virus
... of three human influenza viruses which circulated worldwide for years before the pandemics. Moreover, both clade 7.2 of subtype H5 highly pathogenic avian influenza virus and subtype H7N9 avian influenza virus circulated in poultry in China for years, and they have been virtually eliminated through mass ...
Ref: Potential for elimination of SAR-CoV-2 through vaccination as inspired by elimination of multiple influenza viruses through natural pandemics or mass vaccination [J. med. virol, 2020]As the epidemic spread, SARS-CoV-2 evolved multiple subtypes.
... As the epidemic spread, SARS-CoV-2 evolved multiple subtypes. In a recent study, researchers proposed the subdivision of the global SARS-CoV-2 population into sixteen well-defined subtypes by focusing on the widely shared polymorphisms in nonstructural (nsp3, nsp4, nsp6, nsp12, ...
Ref: cord_uid xhf8yg6o Advances in the relationship between coronavir... xhf8yg6o Advances in the Relationship Between Coronavir... Name: title, dtype: object [J. med. virol, cord_uid xhf8yg6o 2020-05-13 xhf8yg6o 2020-05-13 Name: publish_time, dtype: object]No single solid tumor subtypes were over-represented in the SARS-COV-2 RT-PCR+ subgroup (Table 1 , legend).
... diarrhea, and anosmia/agueusia, as well as suspected COVID-19 pneumonia of CT scan (Table 1) . No single solid tumor subtypes were over-represented in the SARS-COV-2 RT-PCR+ subgroup (Table 1 , legend). Present tobacco use (N=35, 11.6%), former tobacco use (N=61, 20.2%), report of COPD (N=26, 8.6%), ...
Ref: High mortality rate in cancer patients with symptoms of COVID-19 with or without detectable SARS-COV-2 on RT-PCR [Eur J Cancer, 2020-06-07]